Up Front

• The Millisecond Challenge
  Shaw opens the Bio-IT World Expo on the "grand challenge of biology."
• Imaging and Markers
  THE BIOMARKER REPORT -  Pfizer uses imaging and biomarkers for oncology research.
  By Malorye Allison
• Dollars and Sense
  NOTHING VENTURED - Companies' compensation packages are key to success.
  By Michael A. Greeley
• Semantic Web's 'Snap, Crackle, and Pop!'
  SCIENCE AND THE WEB - New recommendations lay out the languages and tools for the Semantic Web.
  By Eric K. Neumann
• News Briefs

• Jewels in the Biobanking Crown
  Biorepository LIMS from LabVantage and Thermo Fisher draw admirers in pharma and academia.
• E-Lab Notebook Flying High
  Rescentris ELN earns wings at U.S. Air Force base. 

Clinical Research

• Change Agents for Adaptive Design
  Tessella sees big pharma changing its tune on adopting adaptive trials.
• Biting the Adaptive Trials Bullet
  Wyeth's Michael Krams on the future of clinical drug development. 

In Every Issue 

• Enabling Technologies
  FIRST BASE - Next-generation sequencing and adaptive trials are both gaining ground, and promise to profoundly impact medicine.
  By Kevin Davies
• Entelos' First Year as a Public Company
  THE RUSSELL TRANSCRIPT - After going public last year, Entelos released its first financial report as a public company, and reports both gains and losses. 
  By John Russell
• New Products