CONFERENCE SERIES: Biological Therapeutic Products
Recorded at: PEGS: The Essential Protein Engineering Summit
Digital Course: Phage and Yeast Display Libraries and Their Screening
About this Product:
This digital course is meant to bring the scientist up to speed on the display technologies covered by the main conference and is tailored for both the novice and those with experience in display technologies.
The course will provide an overview of:
• Phage display and construction of phage-displayed peptide, scFv and Fab libraries
• Yeast display and construction of yeast-displayed scFv and Fab libraries
• Selection and screening technologies that are compatible with phage and yeast-display libraries
About this Product:
Over 176 Minutes
Individual: $345Site License: $1380
Agenda At A Glance:
Andrew M. Bradbury, M.B., B.S., Ph.D., Staff Scientist, Biosciences, Los Alamos National Laboratory
Biography: Andrew Bradbury was trained in medicine at the universities of Oxford and London, and subsequently practiced medicine for five years (one full time, and four part time) in the UK. He received his Ph.D. (Cambridge University) in the MRC Laboratory of Molecular Biology under the guidance of Dr. Cesar Milstein. After his Ph.D. he spent ten years in Italy: three as a post doc in the CNR Institute of neurobiology, Rome, Italy, where he was involved with cloning antibody V regions for use in intra- and inter-cellular immunisation; and seven in Trieste, where he was first visiting professor, and subsequently tenured as assistant professor at the International School for Advanced Studies (SISSA, Trieste, Italy). He has been a research scientist at Los Alamos National Lab since July 1999, and is now group leader.
He has worked in the field of phage display and antibody engineering for twenty years, and has helped organize over forty international congresses and practical courses in this field, both in Europe and the US. He has published over one hundred peer reviewed articles, including a number of reviews and commentaries on phage display.
His present research interests lie in improving present phage display technology as well as developing applications related to the human proteome project. To this aim he has developed a recombinatorial method to make very large phage antibody libraries, a novel phagemid packaging system, and high throughput selection and screening systems. More recently he is working on modifying fluorescent proteins to create “Fluorobodies” – affinity reagents with intrinsic fluorescence, and also on methods to select protein binding domains from genomes.
James Marks, M.D., Ph.D., Professor, Anesthesia & Pharmaceutical Chemistry, University of California, San Francisco; Chief of Anesthesia and Vice Chairman, Anesthesia & Perioperative Care, San Francisco General Hospital
Biography: James Marks received his bachelors degree in Biochemistry from the University of California, Berkley. He went on to earn his M.D. from the University of California, San Francisco where he also completed his Residency in Internal Medicine. After teaching medicine for a few years, Dr. Marks undertook another residency, this time in Anthesthesia, following which he became a professor of Anethesia and Pharmaceutical Chemistry – a position he still holds with the University of California, San Francisco. In 1997 he became the Director of the San Francisco General Hospital Medical-Surgical Intensive Care Unit.
Dr. Marks was a member of Phi Beta Kappa as well as Alpha Omega Alpha. He has received awards such as the Beckman Young Investigator Award (1994) and the CaPCURE Research Award (1995, 1996) and has been published in peer-reviewed journals over 130 times.
About the Conference:
PEGS is the essential antibody and protein engineering event of the year, where what you learn can be directly applied to your work. The event provides 1,200+ participants to network with their peers and learn about unpublished science in the session rooms. Delegates engage in problem solving breakout discussions and gain insight from over 60 exhibitors, and view the 155 posters in the exhibit hall.