Best Practices and Next Generation Solutions for Characterization of Novel Biologics

The popular PEGS Analytical Stream focuses on the application of characterization tools to help gain a detailed knowledge of proteins from discovery through all the stages of development and production.  For 2024, this three-meeting stream offers comprehensive individual programs focused on novel therapeutic modalities, biophysical methods and the implementation and impacts and implementation of digital tools and big data in this function.  The more than fifty conference speakers in this stream will be augmented by focused short courses and hosted roundtable discussions on themes related to this field.

Conferences Include:

May 13-14

Digital Integration in Biotherapeutic Analytics

May 14-15

Biophysical Methods

May 16-17

Characterization for Novel Biotherapeutics

Keynote Speakers Include:

Enabling Pipeline Programs Lead Candidate Selection & Optimization through Data Structure, Statistical Analysis & ML/AI
Marc Bailly, PhD, Principal Scientist, Protein Sciences Analytical Characterization, Merck

Biophysical Characterization across Modalities
George Bou-Assaf, PhD, Associate Director, Analytical Development, Biogen

Phase-Appropriate Analytical Strategies for Developability Assessment and Formulation of Biotherapeutics
Hristo Svilenov, PhD, Associate Professor, Ghent University

2024 PROGRAMS

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• Display of Biologics
• Engineering Antibodies
• Machine Learning for Protein Engineering

• Antibodies for Cancer Therapy
• Emerging Targets for Oncology
• Antibody Drug Conjugates

• TS: Intro to Bispecifics
• Advancing Bispecific Antibodies
• Engineering Bispecific Antibodies

• Advances in Immunotherapy
• Cell-Based Immunotherapy
• In vivo Cell and Gene Engineering

• Difficult-to-Express Proteins
• Optimizing Protein Expression
• Protein Production Workflows

• Digital Integration in Biotherapeutic Analytics
• Biophysical Methods
• Characterization for Novel Biotherapeutics

• TS: Intro to Immunogenicity
• Immunogenicity Assessment and Management
• TS: Intro to Bioassays

• Emerging Indications for Therapeutic Antibodies
• mRNA Therapeutics
• In vivo Cell and Gene Engineering