Cambridge Healthtech Institute’s 11th Annual

Biophysical Methods

New Strategies and Technologies for Next-Generation Analyses of Complex Biologics

May 16-17, 2023


Biophysical analytical methods are now playing an increasingly important role in the discovery and development of next-generation biotherapeutics, and these tools are applied for developability evaluation, structural characterization, understanding aggregation, and as important inputs at different stages of R&D. New informatics and instruments are increasingly allowing these methods to be used in a quantitative, rather than qualitative way – and biophysical studies now play a key role in regulatory filings. New modalities – including cell and gene therapies – are demanding new workflows and new tools to achieve the characterization demands of internal projects and regulatory filings. The PEGS Biophysical Methods conference brings together an international audience of protein scientists and analytical specialists to explore the latest technologies and methods for problem solving in this dynamic field.  


Coverage will include, but is not limited to:


  • Advancing higher-order structure characterization; HOS issues in emerging modalities
  • Automated image analysis
  • Biophysical analysis for new modalities (AAVs, cell therapies, novel protein structures)
  • Correlation of biophysical issues with potency, immunogenicity, duration of response
  • In silico tools and molecular modeling
  • Methods and models for prediction of aggregation and stability
  • Molecular dynamics simulations
  • MS applications and technologies (MAM, instrument combinations, innovations)
  • New methods and instruments for particle analysis
  • Regulatory impacts (new guidance, informal agency requests/trends)
  • Standardization issues in biophysical analysis


The deadline for priority consideration is October 21, 2022.


All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


Opportunities for Participation:



For more details on the conference, please contact:

Kent Simmons

Senior Conference Director

Cambridge Healthtech Institute

Phone: 207-329-2964



For sponsorship information, please contact:

Companies A-K

Jason Gerardi

Senior Manager, Business Development

Cambridge Healthtech Institute

Phone: 781-972-5452



Companies L-Z

Ashley Parsons

Manager, Business Development

Cambridge Healthtech Institute

Phone: 781-972-1340