Cambridge Healthtech Institute’s 15th Annual

Driving Clinical Success in Antibody-Drug Conjugates

Designing the Magic Bullet

May 15-16, 2025

 

As of 2023, the FDA has approved 15 ADC drugs in clinical oncology. More ADCs are expected to receive FDA approval in 2024-2025, a testament to the ongoing excitement and groundbreaking developments in ADCs for cancer treatment. The Driving Clinical Success in Antibody-Drug Conjugates conference will highlight novel payload strategies, including tumor-selective options, degraders, and antisense/siRNA approaches, as well as the potential of multi-payload ADCs. We will also explore advanced engineering techniques aimed at enhancing tumor selectivity, internalization, and penetration, alongside innovations in Fc and linker design. Drawing from clinical experiences, this conference will address strategies to overcome toxicity and drug resistance. By bringing together leading researchers, clinicians, and industry experts, we aim to drive the next wave of ADC innovations and expand their therapeutic reach.

 

  • Novel/Alternate Payloads and Mechanisms-of-Actions
    • Beyond TOPO1 inhibitors
    • Tumor-selective payloads
    • Beyond toxins as payloads—degraders/PROTACs, antisense/siRNA
    • Dual/multiple payloads in one ADC
  • ADC Engineering and Design—Increasing the Therapeutic Window
    • Engineering antibody for more tumor selectivity
    • Engineering ADCs for better internalization and penetration
    • Engineering the Fc
    • Engineering the linkers
  • Overcoming Toxicity and Drug Resistance—Lessons from the Clinic
  • Beyond Oncology
  • Target Diversification

 

The deadline for priority consideration is October 11, 2024.

 

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

 

Opportunities for Participation:

 


For more details on the conference, please contact:

Mimi Langley

Executive Director, Conferences

Cambridge Healthtech Institute

Email: mlangley@healthtech.com

 

For sponsorship information, please contact:

Companies A-K

Jason Gerardi

Sr. Manager, Business Development

Cambridge Healthtech Institute

Phone: 781-972-5452

Email: jgerardi@healthtech.com

 

Companies L-Z

Ashley Parsons

Manager, Business Development

Cambridge Healthtech Institute

Phone: 781-972-1340

Email: ashleyparsons@healthtech.com


Register Now

View By:

Premier Sponsors

FairJourneyBiologics GenScript-CRO Integral-Molecular_NEW  OmniAbUnchainedLabs