Speaker Biographies

Sr Scientist

Johanna Abend received her Ph.D. in Microbiology and Immunology from the University of Michigan, Ann Arbor in 2008, where the focus of her research was aimed at investigating cytokine-mediated regulation of the human polyomavirus BKV. She continued her training in virus-host interactions with a post-doctoral fellowship at the NCI/NIH in Bethesda, MD where she investigated cellular targets of Kaposi’s sarcoma-associated herpesvirus (KSHV) microRNAs, with a particular interest in immune-related targets (TWEAKR and IRAK1). Following her post-doctoral training, she worked at the Novartis Institutes for BioMedical Research (NIBR) in Emeryville, CA as an investigator and Project Team Leader for multiple antiviral drug discovery teams targeting polyomaviruses and Hepatitis B virus (HBV) using both biologics and small molecule modalities. After seven years at Novartis, Johanna joined BioMarin in January of 2019 as a Senior Scientist in Immunogenicity Assessment where she has supported the filing of a supplemental BLA for Palynziq, a PEGylated enzyme substitution therapy for the treatment of PKU. Johanna has over 8 years of industry experience in antiviral drug development and immunology.

Dir of Bioassay

Marla Abodeely has been working in the Bioassay/Immunoassay field for over 12 years. During this time, she has worked with both small and large biotech companies in all stages of product development, from discovery to post-commercialization. Her primary focus has been protein therapeutics, including enzymes, GPCRs, fusion proteins and antibodies. She is currently the Director of Bioassay within the Global Manufacturing Sciences & Technology (MSAT) group at Sanofi Genzyme located in Framingham, Ma. Previously, she was Associate Director, Head of Bioassay/ Immunoassay (Potency and Process Residuals) within the Analytical Method Development group at Shire Pharmaceuticals (now Takeda). She received her B.S. in Biology at Columbia University in New York, NY with a focus in molecular genetics and earned her Ph.D. in the Biomedical Sciences at the University of California, San Francisco (UCSF) with a focus in biochemistry and cell biology.

Massachusetts Institute of Technology

McGovern Fellow/Principal Investigator

Omar Abudayyeh, Ph.D., is a McGovern Institute Fellow at MIT where he runs a small research group on exploring microbial diversity for new biotechnological tools related to genome editing and gene delivery. He completed his training at Harvard Medical School and the Harvard-MIT Health Sciences and Technology program as a graduate student in Feng Zhang’s lab. His graduate research centered on uncovering novel CRISPR enzymes beyond Cas9 for applications in genome editing, therapeutics, and diagnostics. He co-led the discovery and characterization of multiple landmark pieces of work, including the characterization of Cpf1/Cas12 for novel genome editing applications and the first single-protein RNA-guided RNA-targeting enzyme C2c2/Cas13. His follow-up work on C2c2/Cas13 biology led to the development of the SHERLOCK technology for CRISPR diagnostics, and a new set of tools for precise RNA editing for gene therapy. Dr. Abudayyeh is a co-founder of Sherlock Biosciences and an advisor for Beam Therapeutics. In recognition of his technology developments, Dr. Abudayyeh was recognized as 2018 Forbes 30 under 30 in Science and Health Care and Business Insider 30 under 30. Dr. Abudayyeh graduated from MIT in 2012 with a B.S. in mechanical engineering and biological engineering, where he was a Henry Ford II Scholar and a Barry M. Goldwater Scholar.

CSO

Dr. Adams is Chief Scientific Officer of Elucida Oncology, a clinical stage company developing antibody-toxin fusion proteins for the treatment of cancer. In this role he is responsible for guiding the development of the company’s pipeline assets. Before moving to biotech, Dr. Adams was the Director of Biological Research and Therapeutics and previously co-led the Developmental Therapeutics Program at the Fox Chase Cancer Center, an NCI designated comprehensive cancer center in Philadelphia. Dr. Adams is an immunologist with over 30 years of experience in developing antibody-based agents for the treatment and detection of cancer. He received a Ph.D. in Immunology from the University of California at Davis in 1991. He joined Fox Chase Cancer Center in Philadelphia where he led a laboratory focused on developing antibodies and antibody-drug conjugates for the treatment of breast, ovarian and renal cancer. Dr. Adams serves on the Editorial Boards of Cancer Immunology Research, MAbs and Cancer Biotherapy & Radiopharmaceuticals. He has served on the Scientific Advisory Boards of a number of biotechnology companies including Endo Pharmaceuticals, Symphogen, Avipep, Viventia Bio, AvidBiologics, Xerion, Fabrus, Integral Molecular and YM Biosciences.

Assoc Prof

Dr. Adler received his Ph.D. in 1993 from Columbia University where he studied hormonal regulation of gene expression. His post-doctoral research at The Johns Hopkins University School of Medicine focused on studying T cell tolerance pathways, and how they impact tumor immunity. His laboratory at the UConn Health School of Medical currently studies how costimulatory agonists overcome T cell tolerance to tumor antigens, and how this knowledge can be leveraged to boost the efficacy of agonist immunotherapy.

Memorial Sloan Kettering Cancer Ctr

Asst Prof Surgery & Deputy Chief

Dr. Prasad Adusumilli is a thoracic surgeon in New York, New York and is affiliated with Memorial Sloan-Kettering Cancer Center. He received his medical degree from Guntur Medical College NTR and has been in practice for more than 20 years.

President and CSO

To be added

Scientist

Ramon Alemany did his PhD in Biology at the University of Barcelona. Since 1993, he held postdoctoral positions at the MD Anderson Cancer Center, Baxter Healthcare, and the University of Alabama at Birmingham. In 2001, he joined the Catalan Institute of Oncology/Institute of Biomedical Research of Bellvitge. He is author of numerous papers on oncolytic adenoviruses, co-founder of VCN Biosciences, and former President of the Spanish Society of Gene and Cell Therapy.

Sr. Scientist II

Amr Ali’s research focuses on leveraging multi-omics techniques to improve bioprocesses as well as developing new analytical methods for characterization of complex therapeutic proteins. He has been at Biogen for 9 years and had many roles throughout his tenure there ranging from raw material analysis, cell culture development and protein characterization. Amr Ali has a PhD in analytical chemistry from Northeastern University as well as a master’s degree in bioinformatics and a bachelor’s in biomedical engineering from Boston University.

Associate Director

Dr. Alonzo currently leads the Immuno-oncology characterization and analytics team in the Process and Analytical Development Department at bluebird bio. His research focuses on development of analytical and characterization assays for the CARs T/TCR cell program. Prior to bluebird bio, Dr. Alonzo led efforts developing T cell-based therapies at Agenus (Lexington, MA), and previous to his work at Agenus, he was a postdoctoral fellow at Massachusetts General Hospital/Harvard Medical School where he worked on a mouse model of T cell acute lymphoblastic leukemia. Dr. Alonzo received his PhD from the Cancer Biology Program at the Memorial Sloan-Kettering Cancer Center.

Asst Prof

Dr. Alves received his PhD in Chemical and Biomolecular Engineering from the University of Notre Dame. The research he conducts, while spanning many disciplines, is centered on the development of translational technologies, treatments, and techniques that can be utilized to have a positive impact on people’s lives. He has extensive experience in: site-specific antibody modification, oriented antibody immobilization for advanced diagnostics, nanoparticle delivery, and packaging of pharmaceutical agents/enzymes to treat various diseases. Currently, Dr. Alves is an Assistant Professor at the Indiana University School of Medicine in the Department of Emergency Medicine with a joint appointment at Purdue in Biomedical Engineering. His multidisciplinary background affords him a unique perspective to tackle complex medical device and therapeutic development problems.

Exec Dir Oncology Research

Tara Arvedson, Executive Director in Oncology Research at Amgen, has led multiple T cell therapeutic programs and is currently responsible for a large portfolio of T cell therapeutic assets and platform strategy. She received her Ph.D. at Caltech and was later a Damon Runyon Cancer Research Fellow at UC San Diego.

Senior Research Associate

Madhukar Aryal has more than a decade of experience in the bioanalytical sciences and clinical laboratory science. He obtained his Master's in Biochemistry from the University of Utah. He is currently working as a Senior Research Associate II at Biomarin Pharmaceutical.

Principal Scientist

Marc Bailly obtained his PhD in Biochemistry from University Louis Pasteur in Strasbourg, France in Pr. Daniel Kern’s team. After two postdocs in bioinformatics and human T cell development, Marc joined Merck in 2015 where he focused on high throughput analytical characterization technologies enabling lead candidate selection for biologics programs. Marc also worked at MacroGenics focusing on the DART bispecific platforms. Currently Marc is co-leading the analytical characterization group at Merck South San Francisco site. He is focusing on analytical characterization and high throughput data management using bioassays to facilitate the development of machine learning algorithms aiming at predicting developability profiles of antibodies and other biologics modalities.

Assoc Dir

No bio available.

Group Leader, Chemical Biology, Catalent

No bio available.

Scientist III

Alexey Berezhnoy is a scientist in the Cell Biology and Immunology group at MacroGenics, Inc., which he joined in 2016 from a faculty position in the Department of Medicine University of Miami. Dr. Berezhnoy has been active in tumor immunology research for the past 10+ years, focusing on novel therapeutic approaches, including multi-specific molecules and tumor-targeted therapies. Dr. Berezhnoy has authored several high-impact publications in the field of immune oncology.

Imre Berger was trained at Leibniz University Hannover (Germany), MIT (USA) and ETH Zurich (Switzerland), Imre held faculty positions at ETH and EMBL before joining University of Bristol, UK in 2014. AT Bristol, he is Professor and Chair in Biochemistry and Chemistry, Director of the Bristol synthetic biology research centre BrisSynBio and Co-Director of the Bristol biodesign institute BBI. Imre published more than 100 papers in leading journals, co-founded three biotech companies and won several distinctions including the Swiss Technology Award, the Swiss Venture Award (2nd prize), the DeVigier Foundation Award and a Wellcome Trust Senior Investigator Award for his innovative research. Since 2019, Imre Berger is Investigator of the European Research Council (ERC) and Founding Director of the Max Planck Bristol Centre for Minimal Biology.

Asst Prof

No bio available.

Assistant Attending Physician

Allison Betof Warner, MD, PhD is an Assistant Attending Physician on the Melanoma Service at Memorial Sloan Kettering Cancer Center. Dr. Betof graduated with her MD/PhD from the Medical Scientist Training Program at Duke University. She completed her PhD under the supervision of Drs. Mark Dewhirst and Lee Jones, studying the effects of exercise on tumor angiogenesis and chemotherapeutic efficacy. Dr. Betof went on to Internal Medicine residency at Massachusetts General Hospital then Medical Oncology Fellowship at Memorial Sloan Kettering Cancer Center. Her research explores how modulations in tumor microenvironment affect tumor immunobiology and immunotherapy. Her clinical research focuses on duration of immunotherapy treatment in complete responders and novel therapies for PD-1 refractory disease.

Dir Experimental Medicine Lab

Nicoletta Bivi received her Master’s degree in Biotechnology from the University of Trieste in 2003 and subsequently completed a PhD in Molecular Biology from the University of Udine in 2008. Dr. Bivi joined Eli Lilly and Company in 2012 from Indiana University School of Medicine, where she was an Assistant Professor. In her current role as the Director of Assay Development, Dr Bivi leads a team of scientists who develop novel biomarker, target engagement, and immunogenicity assays to support all therapeutic areas and phases of Eli Lilly and Company’s portfolio. In addition, Dr Bivi’s laboratory contributes to the assessment of pre-clinical immunogenicity risk. Dr. Bivi’s interests include immunoassays and mechanisms of immunogenicity. Recently, her laboratory was the first to demonstrate that pre-existing reactivity assessment of biotherapeutics can predict clinical immunogenicity and the epitope(s) targeted by the anti-drug antibodies. Dr. Bivi is the author or co-author of more than 20 peer-reviewed scientific papers.

Gyroscope Therapeutics

VP

Alex Bloom serves as VP Regulatory Affairs and Quality Assurance at Gyroscope Therapeutics, a UK-headquartered company focused on developing products and surgical delivery devices to preserve sight and fight the devastating impact of blindness. Gyroscope’s leads investigational gene therapy, GT005, is in development to treat the leading cause of blindness, dry age-related macular degeneration (dry AMD). Prior to Gyroscope, Alex has spent the past decade working on the development and regulation of cell and gene therapies. He has worked on over 40 ATMP programs, including as the regulatory lead for Holoclar®, the first stem cell-based medicine to receive approval in the West. Prior to working in Regulatory Affairs, Alex spent time in manufacturing and process development positions for recombinant protein products. He received his PhD from the University of Sheffield (UK).

SVP and CSO

Ezio Bonvini joined MacroGenics in 2003 after a career at the National Cancer Institute, NIH, and the Center for Biologics Evaluation and Research, FDA, where he last served as the Chief of the Laboratory of Immunobiology and the Acting Deputy Director of the Division of Monoclonal Antibodies. A physician by training, Dr. Bonvini is an expert in immunobiology and drug development, has authored numerous publications in the field of signal transduction, immunology and immune-oncology, and is an inventor on several patents.

VP Translational Medicine

Adrian Bot, MD, Ph.D., is the Vice President of Translational Medicine at Kite, a Gilead Company, developing genetically engineered cell products for oncology indications. Dr. Bot has more than 20 years of experience in the biopharmaceutical industry with focus on discovery and development of immunotherapies. He obtained his M.D. in Romania in 1993 and his Ph.D. in Biomedical Sciences at Mount Sinai School of Medicine in New York in 1998. Subsequently, he was a Guest Scientist at the Scripps Research Institute in La Jolla, California. Prior to his appointment as Chief Scientific Officer at Kite Pharma in 2011 and then Vice President of Translational Medicine, where he contributed to the development of a first-in-class cell therapy product, Dr. Bot served in various senior R&D leadership positions at MannKind Corp, and Alliance Pharmaceutical Corp. His prior activities include serving on editorial boards and leadership appointments in global professional societies.

Sr Scientist

George has a BS in chemistry and a PhD in Biochemistry. His graduate studies under Prof. Alan Marshall at Florida State University focused on development and optimization of hydrogen/deuterium exchange mass spectrometry to study protein-protein interactions. Shortly after he graduated, he joined the technical development group at Biogen in 2011 where his job responsibilities focus on the biophysical characterization of proteins and gene therapy products.

Ablynx NV, a Sanofi Company

Head

Carlo Boutton obtained his PhD in 1999 at the University of Leuven (Belgium) on a subject that investigated the physico-chemical behavior of proteins under high-electromagnetic (laser) fields. After his PhD he joined Algonomics (currently Lonza) where he contributed to the development of EpiBase: a platform to predict and identify T-cell epitopes in biologics. In 2003 he joined Tibotec (subsidiary of Johnson & Johnson) where he was involved in several anti-HIV and anti-HCV projects. He joined Ablynx in 2007 where he focused on improvements of the Nanobody platform and new therapeutic applications for Nanobodies, including bispecifics, immunotherapeutics and ADCs. After the acquisition of Ablynx by Sanofi he holds the position of Head Nanobody Explorative Technologies. Together with his team he is working on a next generation Nanobody platform.

CSO

Andrew Bradbury was trained in medicine at the universities of Oxford and London, and subsequently practiced medicine for five years (one full time, and four part time) in the U.K. He received his PhD (Cambridge University) in the MRC Laboratory of Molecular Biology under the guidance of Dr. Cesar Milstein. After his Ph.D. he spent 10 years in Italy: three years as a post doc in the CNR Institute of neurobiology, Rome, Italy; and seven years in Trieste, where he was first visiting professor, and subsequently tenured as assistant professor at the International School for Advanced Studies (SISSA, Trieste, Italy). He was a staff scientist and group leader at Los Alamos National Lab from July 1999 to June 2017, when he left to join Specifica, a startup he founded that specializes in antibody selections and selling unique antibody libraries. He has worked in the field of phage display and antibody engineering for 25 years, and has helped organize over forty international congresses and practical courses in this field, both in Europe and the U.S. He has published over 130 peer-reviewed articles, including a number of reviews and commentaries on phage display and antibody engineering. He is one of the founding members of “The Antibody Society”, and is on the editorial board of three journals.

Head, Professional Services

Dr. Arnd Brandenburg joined Genedata in 2005 and heads the Professional Services team of the Expressionist business unit. Before joining Genedata, Arnd worked as a theoretical physicist at DESY, Hamburg, doing research in particle physics and cosmology. He did his Ph.D. in physics at the University of Heidelberg and is a lecturer for bioinformatics and systems biology at the University of Freiburg.

Senior Vice President & Head

Ingmar is Vice President of Clinical Development of the Company. Prior to joining Pieris, from 2013 through October 2017, Dr. Bruns led clinical development of several high priority oncology assets at Bayer Pharmaceuticals. Before his tenure at Bayer, Dr. Bruns served as an attending hematologist and oncologist as well as a basic, translational and clinical researcher at the University Hospital of Dusseldorf in Germany and Albert Einstein College of Medicine in New York. Dr. Bruns has authored over 50 papers in the field of hematology and oncology. He received his MD and PhD from the University of Lubeck in Germany.

University of Alabama, Birmingham

Professor & Director

Donald J. Buchsbaum is a Professor of Radiation Oncology, Surgery, Pathology, Pharmacology & Toxicology, Biomedical Engineering, and Biochemistry & Molecular Genetics at the University of Alabama at Birmingham School of Medicine and plays a leading role in the breast and pancreatic cancer translational research programs that focus on the clinical development of therapeutic agents. These include monoclonal antibodies against epidermal growth factor receptor and TRAIL death receptor 5, small molecule Wnt/ß-catenin inhibitors, plus genomic analysis and precision medicine. Combinatorial studies are investigated with chemotherapy and radiation therapy. In addition, he is investigating therapeutic agents against breast and pancreatic cancer stem cells and immune-based therapies. He is the Co-Leader of the Inflammation, Immunology, and Immunotherapeutics Program in the University of Alabama at Birmingham O'Neal Comprehensive Cancer Center.

Chief Business Officer

Dr. Rob Burgess is currently Chief Business Officer at Sino Biological, Inc. and has over 25 years of scientific and business development experience.  His previous position was Vice President, Global Business Development at RayBiotech. Dr. Burgess holds a Ph.D. in molecular biology from the M.D. Anderson Cancer Center in Houston. 

Principal Scientist

Iain Campuzano works in and manages a core analytical research group within Amgen Research. He has invented/co-invented six mass spectrometry related patents and published over 50 peer reviewed articles and book chapters. He has also presented and organised/chaired sessions at multiple international conferences such as ASMS, ASMS Sanibel, PEGS, Discovery on Target and PITTCON.

Genentech Fellow

Dr. Carter received a B.A. in Natural Sciences from Cambridge University and his Ph.D. in Molecular Biology under Sir Greg Winter at the MRC Laboratory of Molecular Biology in Cambridge. He then completed a postdoctoral fellowship with Dr. Jim Wells at Genentech, now a member of the Roche Group. Dr. Carter has over thirty years of experience in biotechnology, focusing on the discovery of antibody therapeutics. He played a key role in the creation of antibody humanization methods at Genentech utilized over many years for nine approved antibody products used to treat millions of patients worldwide. Dr. Carter and collaborators invented ‘knobs-into-holes’ technology widely used in generating bispecific antibodies. He is currently a Genentech Fellow in the Department of Antibody Engineering.

Vice President, Antibody Discovery

Ross Chambers is Vice President of Antibody Discovery at Integral Molecular. He pioneered the use of DNA immunization for antibody production and developed Integral Molecular’s B-cell cloning system for antibody isolation. Before joining Integral Molecular, Dr. Chambers was Director of R&D at SDIX, where he directed the discovery of thousands of commercial antibodies.

Executive Director

Javier worked for 8 years in the field of enzyme engineering and received his PhD in 2003. After his postdoctoral training he joint Pfizer, where he is leading the BioTherapeutic Discovery department within Biomedicine Design. In this role, he is responsible for leading biotherapeutic discovery work, including lead generation and optimization, structural based design, biophysical characterization, and non-GLP biotherapeutic production. Javier is interested in understanding the underlying biology of drug design and delivery and engineering solutions for challenges associated with developing the next generation of biotherapeutics.

VP Research

Cécile Chartier, Ph.D., is currently serving as Vice President of Research at Iovance Biotherapeutics. She led OncoMed Pharmaceuticals' Target Validation group from 2005 to 2017 as a Senior Director. From 2001 to 2004, Dr. Chartier was Scientist III in Berlex Biosciences’ Gene Therapy department. She had started her career as a scientist at the French Biotechnology company, Transgene. Dr. Chartier is a Molecular Biologist by training. She obtained her Bachelor’s, Master’s, and Ph.D. in 1987, 1988, and 1993 from the Université Louis Pasteur of Strasbourg, France. She pursued a post-doctoral training at Harvard Medical School in Boston from 1997 to 2000, followed by one year at Stanford University in 2001.

Asst Prof

Chen joined the Yale Faculty in 2015 as an assistant professor in the Department of Genetics and Systems Biology Institute, also as a member of the Yale Cancer Center and the Yale Stem Cell Center. Chen earned a PhD in evolutionary genetics from The University of Chicago with an award-winning dissertation with Dr. Manyuan Long. After graduation he performed postdoctoral studies at MIT under the mentorship of Dr. Phil Sharp, and also the Broad Institute working with Dr. Feng Zhang. His research focuses on providing a global understanding of biological systems. Chen developed and applied genome editing and high-throughput screening technologies, precision CRISPR-based in vivo models of cancer, global mapping of functional drivers of cancer oncogenesis and metastasis. More recently, he developed novel systems that enable rapid identification of novel immunotherapy targets and new modalities of cancer immunotherapy. Dr. Chen received a number of national and international awards including the NIH Director’s New Innovator Award, Damon Runyon Cancer Research Fellow, Dale Frey Award for Breakthrough Scientists, AACR NextGen Award for Transformative Cancer Research, TMKF Innovative/Translation Cancer Research Award, BCA Exceptional Research Grant Award, MRA Young Investigator Award, V Scholar, Bohmfalk Scholar, Ludwig Family Foundation Award, St. Baldrick’s Foundation Award, CRI Clinic & Laboratory Integration Program (CLIP), MIT TechReview Regional 35 Innovators, and Sontag Foundation Distinguished Scientist Award.

Massachusetts Institute of Technology

Research Scientist

Dr. Chen is a surgeon, engineer, and multidisciplinary scientist with a career vision to improve human health. Dr. Chen is currently a Research Scientist at Massachusetts Institute of Technology (MIT). He received his M.D. degree and medical training (internship and surgical residency) in Taiwan before pursuing an academic path. Dr. Chen obtained his Master’s degree in Biotechnology at the University of Pennsylvania and Ph.D. degree in Bioengineering at the University of Pittsburgh. He finished his first postdoctoral fellowship in Biomaterial and Regenerative Medicine at the University of Pittsburgh. Dr. Chen recently finished his NIH-sponsored joint postdoctoral fellowship at MIT and Massachusetts General Hospital (MGH) under the co-mentorship of Dr. Timothy Lu (MIT) and Dr. Anthony Rosenzweig (MGH). Dr. Chen’s research is focused on the development of platform technologies for precision biomanufacturing and cardiovascular translational medicine using genetic engineering and synthetic and systems biology approaches.

Robert Winthrop Professor

George M. Church, PhD ’84, is professor of genetics at Harvard Medical School, a founding member of the Wyss Institute, and director of PersonalGenomes.org, the world’s only open-access information on human genomic, environmental, and trait data. Church is known for pioneering the fields of personal genomics and synthetic biology. He developed the first methods for the first genome sequence & dramatic cost reductions since then (down from $3 billion to $600), contributing to nearly all “next generation sequencing” methods and companies. His team invented CRISPR for human stem cell genome editing and other synthetic biology technologies and applications – including new ways to create organs for transplantation, gene therapies for aging reversal, and gene drives to eliminate Lyme Disease and Malaria. Church is director of IARPA & NIH BRAIN Projects and National Institutes of Health Center for Excellence in Genomic Science. He has coauthored 450 papers, 105 patents, and one book, “Regenesis”. His honors include Franklin Bower Laureate for Achievement in Science, the Time 100, and election to the National Academies of Sciences and Engineering.

Shriram Chair & Professor

Jennifer Cochran is the Shriram Chair of the Department of Bioengineering at Stanford University. She is a Professor of Bioengineering and, by courtesy, Chemical Engineering and a member of the Cancer Biology, Biophysics, and Immunology graduate programs. Dr. Cochran serves as the Director of the Stanford/NIH Biotechnology pre-doctoral training program, and co-Director of the Stanford NIST pre-doctoral training program. Her research group uses interdisciplinary approaches in chemistry, engineering, and biophysics to study complex biological systems and to develop new tools for basic science and biomedical applications. Dr. Cochran translational interests span protein-based drug discovery and development for applications in oncology and regenerative medicine, and development of new technologies for high-throughput protein analysis and engineering. Dr. Cochran obtained her Ph.D. in Biological Chemistry from the Massachusetts Institute of Technology, where she also completed a postdoctoral fellowship in Biological Engineering.

Scientist

Dr. Sivan Cohen is a scientist in the Department of BioAnalytical Sciences (BAS) at Genentech. A trained immunologist, She received her Ph.D. in Immunology from the Weizmann Institute of Science and conducted her post-doctoral training in Duke University. Sivan joined Genentech in 2017, and currently leads the development and implementation of in silico and in vitro bioanalytical assays to support evaluation of immunogenicity potential of Genentech’s biotherapeutic products.

Sr Scientist & Grp Leader

Dr. Coleman is a senior biomedical staff scientist at Lawrence Livermore National Laboratory and an adjunct professor in the department of Radiation Oncology at University of California Davis School of Medicine and. He received his Ph.D. in molecular biochemistry and cellular biology from Boston University. Dr. Coleman has authored over 150 publications in peer-reviewed journals, published proceedings and book chapters covering a diverse breadth of molecular biology and biochemistry. He has over 19 years experience in developing biotechnology and characterizing genomic responses of genotoxic stressors such as ionizing radiation.

Associate Director, Cell Therapy

Anthony has led several genome editing research programs at Sangamo over the past 7 years and has been working in the gene and cell therapy field for over 12 years. His group is currently primarily focused on developing genome-edited regulatory T cell therapies for solid organ transplant tolerization and autoimmune disorders. His group is also developing non-viral delivery technologies for both in vivo and ex vivo genome editing therapeutic strategies.

Asst Prof

The goal of my research program is to elucidate the structural basis by which post-translational modifications (PTMs) regulate cellular signaling systems. A long-standing challenge that has hindered progress in this field is our inability to programmably produce biologically relevant, multiply-modified proteins in sufficient quantities and homogeneity for structural biology applications. Genetic Code Expansion is a unique technology that enables co-translational installation of PTM amino acids into proteins at genetically programmed sites, but poor efficiency, premature protein truncation and mis-incorporation of natural amino acids have limited its broad utility. My laboratory aims to develop improved core GCE technologies for efficient and accurate incorporation of PTMs and their analogues into biologically relevant protein complexes for structural and biochemical characterization. Given the countless diseases associated with mis-regulation of PTM-proteins and a sobering lack of structural knowledge about them, this research hopes to facilitate future development of drugs and anti/nanobodies that target these pathways.

Asst Scholar & Core Mgr

Dr. Alicja Copik is a biochemist specializing in innate immunity with emphasis on NK cell biology in the context of immunotherapy for treatment of cancer. Her laboratory has developed a method for NK cell expansion that is simple, safe, economical and effective, which can be applied in vitro or in vivo. This novel method is based on the use of PM21-particles derived from plasma membranes of cells engineered to stimulate NK cell expansion. This technology is clinically relevant and is now being translated for clinical studies for treatment of leukemia and other malignancies. Dr. Copik has diverse expertise from chemical engineering, medicinal organic chemistry, enzymology, biomolecular interactions, molecular and cell biology and she worked in academia, hospital and industrial settings.

Senior Staff Scientist

Dr. Crawford is a Senior Staff Scientist in the department of Oncology and Angiogenesis at Regeneron Pharmaceuticals, Inc where she has worked since 2011. She completed her BSc in Immunology from Glasgow University before being admitted to the Wellcome Trust PhD program at Edinburgh University where she focused on T cell memory. Her post-doctoral work at the University of Pennsylvania examined T cell exhaustion during chronic viral infection and the role of checkpoint inhibition in alleviating T cell exhaustion. This piqued her interest in immunotherapies and she made the transition into industry at Regeneron Pharmaceuticals where she currently leads a group developing pre-clinical models to examine bispecific antibodies targeting solid tumors. She led the in vivo pre-clinical research efforts on REGN4018 (MUC16xCD3) to advance the antibody through to IND submission.

Dir Translational Research Labs & Asst Prof

No bio available.

Queensland University of Technology

Dr

Dr. Zhenling Cui is a research associate at the Queensland University of Technology (Australia). She completed her PhD degree in Chemical and Biological Sciences at the University of Queensland in 2016 and then received Dean’s received Dean’s award for outstanding higher Degree by research. Her research interest lies in the field of protein engineering, synthetic biology and genetic code expansion technology. Her research has focused on exploiting redundancy of the genetic code and she has made significant contributions primarily to understanding the role of synthetic transfer RNAs (tRNAs) and their usage in terms of adapting the connection between sense codons and various unnatural amino acids with bio-orthogonal groups for future application in producing cyclized peptides, antibody drug conjugates (ADCs) and probes for structural conformation analysis.

Novartis Institutes for BioMedical Research Inc

Sr. Research Investigator/Lab Head

Tony D’Alessio is a Senior Research Investigator and Lab Head in the Oncology Biotherapeutics group at the Novartis Institutes for Biomedical Research where he works on antibody drug conjugates and other novel biologics-based therapeutic approaches to targeting tumour and immune cells. Prior to Novartis he held positions at Igenica, Inc. and the Janelia Farm Research campus of HHMI.

Associate Director, Automation Lead

I have spent most of my Biopharma career involved in protein biochemistry. I started in the early 2000s at Wyeth, purifying proteins for structural studies. I then joined the Structural Protein Chemistry (SPC) group at Genzyme in 2010, where my main focus was using a variety of analytical techniques to define protein structure-function relationships. I left the group in 2013 to work for Warp Drive Bio. I mainly focused on mass spectrometry proteomics for target identification and high-throughput mass spectrometry screening methods for candidate compounds. I re-joined the SPC group, now known as the Characterization Group for Sanofi, in early 2016, and am using automation to support high-throughput analytics. In 2020, I moved out of the Characterization group to lead a small automation group, focused on removing/eliminating redundancy at the bench and computer.

Director

Hussain Dahodwala obtained his PhD from RPI in 2007 and has since worked at SUNY polytech, NIH VRC labs and University of Delaware where the his research efforts have focused on understanding the role of culture conditions and cell physiology on living systems used for industrially relevant processes. The primary area of interest is the use of mammalian cell systems for the production of therapeutic proteins. He has many publications and review articles on the use of modern cell and molecular biology along with “omics” to probe physiological states, with an objective of optimizing production systems both from an engineering perspective (e.g. culture conditions) as well as from a biological perspective (cellular and metabolic engineering).

Univ of California Los Angeles

Postdoctoral Researcher

No bio available.

Dr

After obtaining her PhD from the University of London in 2001, Claire Davies performed her postdoctoral work at the William Harvey Research Institute (WHRI) at Bart’s and The London, Queen Mary's School of Medicine and Dentistry and Joslin Diabetes Center, Harvard Medical School, Boston. Over the last 18 years, Dr Davies has led analytical and CMC teams in product development and analytical method development and validation. Currently, Dr Davies leads Bioanalytics, a group responsible for developing methods and strategies to support process development, product characterization and release and stability testing for therapeutic proteins and gene therapy products in preclinical and clinical development.

Dir

Dr. Rupert Davies currently serves as a Director within Translational Sciences at Zymeworks, where he is responsible for the development of drug candidates from the hit discovery stage through to IND-enabling studies and into FIH clinical trials. Dr. Davies was part of the Zymeworks team that enabled the advancement of ZW25 and ZW49 into the clinic and he and the team are now focused on combining Zymework’s Azymetric™ Bispecific and ZymeLink™ Antibody Drug Conjugate (ADC) platforms to develop drug candidates with expanded therapeutic windows. Throughout his career, he has worked on a broad array of drugs modalities from small molecules and peptides to RNA mimics and antibodies, including five candidates that are currently being evaluated in clinical trials and two approved drugs. Prior to his current role, Dr. Davies worked in various roles at small start-ups, medium-sized biotechs and Amgen. He received his PhD in Bioengineering from the University of Utah and completed a post-doctoral fellowship in Bioengineering at the University of Washington.

Head

Jonathan Davis, PhD is Head of Innovation at Invenra, Inc. Headquartered in Madison, Wisconsin, Invenra is focused on discovery and development of human IgG-like multispecific antibodies for immuno-oncology and autoimmune disorders. A thought leader in the field of bispecific antibodies for over a decade, Dr. Davis has 18 years of industry experience (Bristol-Myers Squibb, EMD Serono) as a protein engineer and platform developer focusing on antibodies and multispecific biotherapeutics, covering a wide variety of therapeutic areas. Dr. Davis holds a PhD in biophysics from UC San Francisco, which he followed with a postdoctoral fellowship at Harvard Medical School.

Asst Prof & Head

Kim De Keersmaecker obtained a PhD in the field of cancer biology at KU Leuven (Belgium) in 2008. From 2008 till 2010, she performed postdoctoral research at Columbia University (New York, USA) with Prof. Adolfo Ferrando, studying the role of transcription factor TLX1 in T-cell leukemia. During a second postdoc at KU Leuven (2010-2013), she undertook exome sequencing in T-cell leukemia patients and discovered somatic mutations in ribosomal proteins in cancer. In 2014, Kim received an ERC starting grant and established an independent research lab at KU Leuven studying the role of somatic ribosome mutations in cancer. The excellence of her research is illustrated by publications in leading journals such as Nature Genetics, Nature Medicine, Nature Communications and Molecular Cell.

Asst Prof

Dr. Brandon DeKosky is an Assistant Professor at the University of Kansas Departments of Chemical Engineering and Pharmaceutical Chemistry, where his laboratory leverages recent advances in next-generation DNA sequencing technologies to achieve a more comprehensive understanding of immune function and accelerate the development of new vaccines and therapeutics. During his graduate research, Dr. DeKosky invented the very first technology for sequencing the antibody proteins encoded by B cells at the single-cell level, at a massive scale (for example, over 5 million single B cells in a one-day experiment), which reduced cost and enhanced throughput for antibody sequencing by multiple orders of magnitude compared to traditional antibody discovery platforms. Dr. DeKosky also pioneered the associated bioinformatic methods for rapid statistical analysis of the very large datasets generated by this approach. Ongoing efforts in the DeKosky lab, supported by an NIH Director’s Early Independence Award and a United States Department of Defense Career Development Award, and focus on expanding our ability to determine the mechanisms of protection for human vaccines and to develop novel and improved targeted human therapeutics.

Senior Research Fellow

Dr. Demarest leads the Protein Engineering Department at the Lilly Biotechnology Center, which is responsible for the design, engineering, and mechanistic characterization of proteins, antibodies, and antibody-like molecules. Prior to joining Lilly in 2011, he held positions at Biogen Idec, Diversa Corp., and Syngenta, working as a Protein Chemist/Engineer on antibody and protein therapeutics design and biochemistry. He performed his graduate work at SUNY Stony Brook, studying protein-folding mechanisms. He was a NIH-sponsored postdoctoral fellow at the Scripps Research Institute, studying the structure, folding, and binding of nuclear co-activator proteins.

CEO

Ryan Denomme is the CEO and co-founder of Nicoya, a biotechnology company specializing in Surface Plasmon Resonance (SPR) platforms. As a nanotech engineer and alumni of the University of Waterloo, his relentless passion to solve the challenges faced by researchers is proven by his industry-disrupting products and numerous patents. Under Ryan’s leadership, Nicoya supports hundreds of researchers at leading biotechnology and pharmaceutical organizations to accelerate their next big discovery.

 

Chief Executive and Science Officer

Dr Deonarain studied at Imperial College and Cambridge University where he carried out PhD research into protein engineering. From 1997-2011 Dr Deonarain was a Principle Investigator at Imperial College in Antibody Technology, which led to some novel technologies being developed commercially. Dr Deonarain now retains an honorary position. He has published over 80 papers and patents in protein/antibody engineering/conjugates. In 2014, he co-founded Antikor Biopharma where he is the CEO leading a team to develop the next-generation of antibody-fragment based ADCs

CSO

Dr. Desjarlais is the Senior Vice President, Research and CSO at Xencor, Inc. Since joining Xencor in 2001, Dr. Desjarlais has overseen the company’s engineering, discovery, and preclinical work on antibodies and other proteins. With his coworkers, Dr. Desjarlais has developed several novel technologies for the optimization of antibodies and other proteins, including a platform for generation of bispecific antibodies, and has led the discovery of multiple therapeutic antibody candidates, including CD3 bispecific antibodies, checkpoint bispecific antibodies, and cytokine-Fc fusions for treatment of a variety of diseases. Dr. Desjarlais oversees all of Xencor’s discovery research and preclinical activities, from project conception and candidate generation through preclinical proof-of-concept and early development. Prior to Xencor, Dr. Desjarlais was an Assistant Professor of Chemistry at Penn State University (1997-2001), where he developed and tested methods for the de novo design of protein sequences. He began his work in the field of protein design as a Jane Coffin Childs Fellow at UC Berkeley. Dr. Desjarlais holds a PhD in Biophysics from the Johns Hopkins University and a BS degree in Physics from the University of Massachusetts, Amherst.

Senior Director

Gundo Diedrich received his PhD in Chemistry from the Max-Planck Institute for Molecular Genetics in Berlin. He completed his postdoctoral training in immunology at Yale University, and worked as a Research Scientist in antibody discovery at Targeted Molecules, diaDexus, and Medimmune. In 2015, he joined MarcoGenics as Director Antibody Engineering.

Dir Global Process Analytical development Lead

Julia Ding is a Director, responsible for Global Bioprocess Analytical Development network at Bristol Myers Squibb. She is leading a diverse and dynamic team responsible for enabling analytical for bioprocess development and characterization, rapid analytical technology development, and implementing/advancing CMC control strategy. Her team is driving overall biologic PAT development and strategy for next-generation biologic processes. Dr. Ding also serves in BMS' Biologic Specification Committee and Comparability Council. Prior to joining Bristol Myers Squibb, she was a Manager at PPD, leading a multifunctional analytical development team in quality control testing, assay development, assay validation, assay life cycle management, and product characterization. Dr. Ding obtained her Ph.D. in Physical Organic Chemistry from Emory University and a postdoc from University of California at Berkeley.

President & CEO

Dr. Dixit is an accomplished executive, inventor, and scientist with over 30 years of success with top biotechnology and pharmaceutical companies, including Merck, Johnson & Johnson, and Medimmune-AstraZeneca. Dr. Dixit was selected by his biopharmaceutical peers as the 100 Most Inspiring People in Pharmaceutical Industry by PharmaVOICE in 2015. He is currently the President and CEO of the Bionavigen, LLC, a virtual advisory and drug-hunting company since the middle of 2019. From 2006 to 2019, Rakesh was a Global Vice President of Biologics R&D in AstraZeneca, where he was a key contributor to successful approval of Imfinzi (anti-PD-L1 mab) - lung and bladder cancer; Fasenra (anti-IL-5R afucsolytated mab) - ashthma; Brodalumab (anti-IL-17) in collaboration with Amgen - psoriasis; and Moxetumomab (anti-CD22-PEA immunotoxin) - hairy cell leukemia. At Merck & Co. Inc, (1992-2005), Dr. Dixit was a key contributor to the development of MAXALT (Anti-migraine), SINGULAIR (Anti-Asthma)-1998, CRIXIVAN (Anti-AIDS)-1998; VIOXX (COX-2 Inhibitor)-2000, and EMEND-2003. Dr. Dixit has published 80 peer-reviewed papers in renowned international journals. He has been invited for more than 150 lectures/presentations/workshops in national and international meetings worldwide, and is one of the topmost invited speakers in the biotechnology-biopharma industry. He has special expertise in the development of antibody drug conjugates and biologics of all therapeutic classes.

Scientist

After obtaining his master’s degree from the University of Massachusetts Amherst in 2013, Scott Dooley began working for the Analytical Development department at Sanofi. Over the past 7 years, Mr. Dooley has supported analytical method development and validation for enzyme-replacement therapies, antibodies, and gene therapy products. Currently, Mr. Dooley acts as the analytical team leader within CMC for two products in clinical development.

President and CEO

Ben Doranz (President and CEO, Integral Molecular) has expertise in membrane proteins and antibodies, with 80+ publications, in journals including CellScience, and Nature. Dr. Doranz cofounded the company and has led all aspects of the company’s growth since its inception, bringing five different technologies from research to market.

Cardiologist

Prof. Drum received an MD PhD from the University of Chicago. After a post-doc in Robert Langer's lab at MIT, he moved to National University of Singapore as a faculty where he studies protein engineering and novel methods of protein folding. While at MIT, he received the Burroughs Wellcome Career Award for Medical Scientists. In Singapore, he has been a recipient of the Clinician Scientist Award from the National Medical Research Council.

Zhimei Du earned a Ph.D. from Cornell University Medical College, Immunology Program, studying molecular mechanisms in tumor immunology and autoimmune disease areas. After graduation, she joined Robert G. Roeder’s laboratory at Rockefeller University, studying protein chemistry and epigenetic regulation mechanism. She was later recruited by Regeneron’s bi-specific antibody engineering group. Later, she joined Amgen’s Cell Sciences & Technology department, focusing on cell line and Upstream process development. She then joined Teva Pharmaceuticals building the Upstream development team and labs for innovative biologics pipelines. Currently she is the director of Bioprocess at Merck, leading cell line development, cell banking, and cell therapy process development team. She is also the leader and core member of multiple Industrial-wide Consortium teams, setting up road map and establishing industrial common practices in various biotherapeutics development areas, including ADC/Bispeicifics team at BPOD/NIMBLE, IQ comparability team, IQ sequence variant consortium team, IQ and BPOD monoclonality consortium team.

VP Discovery

Peter Ellmark joined Alligator Bioscience in 2008 and is VP Discovery since 2018. He holds a PhD and an associate professorship in Immunotechnology at Lund University and has more than 20 years’ experience of developing antibodies for immunotherapy of cancer. Dr. Ellmark´s research interest is focused on developing mono- and bispecific antibodies, in particular CD40 targeting therapies, for tumor directed immunotherapy of cancer.

Head

M. Frank Erasmus is the head of bioinformatics at Specifica, Inc. where he specializes in the use of next-generation sequencing technologies to aid in the design of custom therapeutic antibody libraries. Formerly, Frank was awarded a national fellowship from the National Cancer Institute for his translational research associated with B cell precursor acute lymphoblastic leukemia conducted at the Spatiotemporal Modeling Center and Los Alamos National Labs. He brings over 10 years of experience in both biotechnology and academic settings in the development and characterization of therapeutic antibodies using theoretical modeling, bioinformatics and experimental approaches.

Massachusetts General Hospital

Prof in Residence

Soldano Ferrone received his MD and PhD degrees in 1964 and in 1971, respectively, from the University of Milan, Milan, Italy. He has held faculty positions at the University of Milan, Milan, Italy, Scripps Clinic and Research Foundation, La Jolla, CA, Columbia University, New York, NY, New York Medical College, Valhalla, NY, Roswell Park Cancer Institute, Buffalo, NY and at the University of Pittsburgh School of Medicine, Pittsburgh, PA. Since 2012 he is a faculty member of the Department of Surgery at Massachusetts General Hospital, Harvard Medical School, Boston, MA. Dr. Ferrone has received many awards and honors. For the last 30 years he has been the member of many review committees including NIH Study Sections, and of the editorial boards of many scientific journals. Furthermore, he is the member of several external scientific advisory boards. Dr. Ferrone’s research program focuses on the molecular characterization of escape mechanism(s) utilized by tumor cells to avoid immune recognition and destruction and on the development of combinatorial immunotherapeutic strategies to counteract the escape mechanism(s) utilized by tumor cells. These studies are greatly facilitated by the large panel of HLA antigen- and human tumor antigen-specific monoclonal antibodies he has developed and shared with the scientific community over the years. He has described the results of his studies in more than 600 papers published in peer reviewed journals. Moreover, he has been the editor of 14 books and the guest editor of 5 special issues of oncology journals.

CEO

Nicolas Fischer obtained a PhD in Biology from the Department of Molecular Biology University of Geneva on the structure and function of photosynthetic complexes. As a postdoctoral fellow he joined the Group of Sir Greg Winter at the MRC Department of Molecular Biology in Cambridge UK to study protein folding and Antibody engineering using phage display. In 2001 he joined NovImmune and led several therapeutic antibody discovery programs that have reached clinical development stage and developed next generation bispecific therapeutic antibodies. After the successful divestment of the FDA approved anti-INFg antibody Emapalumab, Novimmune now focuses on its bispecific technology under the brand Light Chain Bioscience in which Nicolas serves as CEO.

Chief

David FitzGerald, Ph.D., serves as Chief of the Biotherapy Section, Laboratory of Molecular Biology, CCR, NCI, where his group develops antibody-based therapies for cancer. Frequently, antibodies are modified with toxins to increase their potency, generating immunotoxins or antibody-drug conjugates (ADCs). Constructing such molecules is a core expertise of the Lab. With a few exceptions, unmodified antibodies that target cancer-expressed surface antigens are not cytotoxic. Strategies to improve their therapeutic utility often involve adding payloads. Cytotoxins can be joined recombinantly, when the payload is a gene product (as is the case with immunotoxins), but must be attached chemically when producing ADCs. Our recent focus is targeting cancer-expressed EGFR, where our lead antibody is ‘40H3’ which reacts with EGFRvIII and EGFR when overexpressed on cancer cells, but not on normal cells. We also have a strong interest in cell-death pathways and the role of the tumor microenvironment as it influences the delivery and efficacy of antibody-based cytotoxins.

Senior Scientific Consultant

Amanda Fitzgerald leads a team of scientific consultants at Genedata, who provide solutions for organizations with large molecule and data management needs. She received her doctorate in Biochemistry and Molecular Pharmacology from the University of Massachusetts Medical School and has pharmaceutical industry experience in biotherapeutic discovery and production groups, including scientific support for strategic alliances and development of a high-throughput protein production platform at Pfizer.

Dir Particle Characterization Core Facility

Amber received her Ph.D. in Chemical Engineering within the Pharmaceutical Biotechnology Program with a specialization in the field of immunogenicity of therapeutic protein aggregates at the University of Colorado at Boulder. Amber also holds a Masters in Science from the University of Colorado at Boulder plus a Bachelors of Science from the Colorado School of Mines. She currently holds the position of Director at KBI Biopharma where she manages the Particle Characterization Core which specializes in analytical methods for quantifying, characterizing and identifying submicron, subvisible and visible particulates. Previously, at Amgen, Amber was a Scientist within the biomolecular structures and interactions group where she supported biophysical characterization of protein products with a specialty in subvisible particle characterization and identification. Prior to Amgen, Amber’s experiences include analytical and formulation development for Merck & Co. and collaborations with BaroFold, Inc. to employ high hydrostatic pressure to refold proteins and control subvisible particles.

Researcher

Simon Friedensohn is a PhD candidate in Sai Reddy’s Laboratory of Systems and Synthetic Immunology at ETH Zurich. His research work focuses on developing both experimental as well as computational methods for high-throughput immune repertoire sequencing. He holds a BSc and MSc in Biotechnology from ETH Zurich. Previous to joining the Reddy lab, he completed a scientific internship at Roche where he worked on high-throughput (mi)RNA profiling for comparative genomics.

Section Head Data Science & Computational Design

Upon finishing his studies in Pharmaceutical Sciences, Norbert pursued his interdisciplinary PhD thesis in Computational Life Sciences and Pharmaceutical Chemistry at the University of Bonn focusing on computer-aided design, synthesis, and biological evaluation of protease inhibitors. After starting his professional career at Merck KGaA as Principal Scientist, Norbert joined Sanofi in 2016 as Lab Head for Bioinformatics within the Biologics Research department. Currently Norbert is heading a section for Data Science & Computational Design to support the discovery of next generation protein therapeutics.Upon finishing his studies in Pharmaceutical Sciences, Norbert pursued his interdisciplinary PhD thesis in Computational Life Sciences and Pharmaceutical Chemistry at the University of Bonn focusing on computer-aided design, synthesis, and biological evaluation of protease inhibitors. After starting his professional career at Merck KGaA as Principal Scientist, Norbert joined Sanofi in 2016 as Lab Head for Bioinformatics within the Biologics Research department. Currently Norbert is heading a section for Data Science & Computational Design to support the discovery of next generation protein therapeutics.

Univ Of Illinois Urbana Champaign

Asst Prof

Thomas Gaj is an assistant professor of bioengineering at the University of Illinois Urbana-Champaign. He received his Ph.D. in chemistry from the Scripps Research Institute in La Jolla, CA and performed his postdoctoral training at the University of California, Berkeley. His research lies at the intersection of neuroscience and engineering and is focused on the development of technologies that can facilitate the correction of the inherited and spontaneous mutations that underlie many neurodegenerative conditions.

Director - Antibody Engineering

Raj Ganesan received his Ph.D. at the University of Zurich, Switzerland. Raj is a Protein/Antibody engineer with extensive industry experience (Genentech, MedImmune and Boehringer Ingelheim) in the Design, Development and Characterization of Monoclonal Antibodies, Multi-Specific Biologics and CAR-T. Since 2017, Raj is leading the pre-clinical discovery of biotherapeutics at Janssen R&D (Johnson and Johnson), primarily focused on bispecific antibodies and CAR-T therapies.

Medical Dir Global Drug Dev

Sandra Garces is a rheumatologist with more than a decade of clinical experience, focused on the use of biologic therapies in the treatment of patients with chronic inflammatory diseases. She completed her Ph.D. in the Gulbenkian Institute of Science with a thesis entitled “Clinical Relevance of Drug Immunogenicity”. She developed an algorithm that uses information on drug concentrations and immunogenicity to help guide therapeutic decisions towards more cost-effective therapeutic strategies in clinical practice. In 2016, she joined Eli Lilly & Co., where she has worked on the assessment of the clinical relevance of IMG across different programs. In 2019, she joined Amgen as a Clinical Research Medical Director in the area of inflammation.

Principal Scientist

Melissa Geddie is a Principal Scientist at Biogen, where she works in the Antibody Discovery group. There, she leads efforts to generate antibodies against a variety of targets using multiple modalities, including bispecific and single domain antibodies. Prior to Biogen, Melissa worked at Merrimack Pharmaceuticals, where she led efforts to engineer bispecific antibodies and antibody fragments for therapeutic use. She received her Ph.D. from Emory University, where she focused on protein engineering and performed her postdoctoral studies at the Whitehead Institute for Biomedical Research at MIT.

Head, Target Discovery

Dr. Gee received his B.S. degree in Biology at the California Institute of Technology in 2013, where he published and patented work engineering T cell receptors for adoptive T cell therapy in the laboratory of David Baltimore. Following that, he received his Ph.D. in Immunology with an additional core focus in Computational Immunology at Stanford University in the laboratory of K. Christopher Garcia in 2017, publishing his main work on novel technology to identify the specificities of T cell receptors for application in oncology. He completed further work on characterizing the structural basis of T cell receptor recognition of immunological targets and T cell receptor cross-reactivity. Dr. Gee has had prior work experience at the National Cancer Institute, where his primary focuses were in immunology, structural biology, protein engineering, systems biology, bioinformatics, and algorithms for the application of therapeutic- and early- discovery in immuno-oncology. He is currently Head of Target Discovery at 3T Biosciences since co-founding the company in 2017.

Massachusetts Institute of Technology

Prof

Dr. Gifford leads combined computational and experimental programs that apply machine learning to therapeutic development. His laboratory has developed machine learning methods for designing the complementarity-determining regions of human antibodies that allows for the simultaneous optimization of antibody affinity and target specificity; the discovery of CRISPR gRNAs that can repair disease phenotype without a repair template; and the discovery of novel differentiation conditions to guide stem cells to desired therapeutic fates. He is Professor of Electrical Engineering and Computer Science and Professor of Biological Engineering at MIT, and Affiliated Faculty of the Harvard Stem Cell Institute.

Sr Research Scientist

Julia Gilden, PhD is a Senior Scientist at Promega Corp and specializes in the development of bioassays for immuno-oncology applications. She received her PhD in Biomedical Sciences with a focus in immunology from the University of California, San Francisco and completed postdoctoral training in cell biology and parasitology at the University of Wisconsin Madison.

Sr Scientific Mgr

Dr. Gill received his Ph.D. in Biochemistry and Structural Biology from Dartmouth College and completed his post-doctoral research at the Thayer School of Engineering at Dartmouth. In his previous roles, he worked at ImmunoGen, Bio-Architecture Lab, and Sutro Biopharma. His research interests include protein purification, biochemical assay development, protein engineering, affinity analysis, automated process development, and bioinformatics. Currently, he is Senior Scientific Manager in the Antibody Engineering department at Genentech, where he oversees efforts in automated high-throughput protein production, design, implementation, and maintenance of automated workflows for antibody discovery and engineering, as well as software and automated workflow development for efficient process management. His research group focuses on developing and implementing automated high-throughput technologies for production and characterization of naturally derived and engineered antibodies, antibody fragments, as well as other novel therapeutic formats.

Director

John is a 24-year biotech veteran in Cell Line Development with expertise in monoclonality and single cell isolation. He also has experience ranging from cell banking and upstream process development to Discovery efforts as a Pre-Clinical Program Lead in both large pharma and CDO/CMOs.

Principal Scientist

I am currently leading the recombinant protein production efforts of the RAS Initiative at the Frederick National Laboratory in Frederick, MD.

Prof

I received my PhD in 1978 from UC Davis and trained as a postdoctoral fellow at the Johns Hopkins University School of Medicine and UC San Francisco. I have been a professor at UC Irvine since 1985. The focus of my laboratory is to understand the structure of amyloids, their assembly pathways and their mechanisms of pathogenesis in neurodegenerative disease, like Alzheimer’s disease. The goal of this work is to facilitate the development of effective diagnostic and therapeutic agents. Amyloids form an ensemble of common structures, including parallel, in-register fibrils, anti-parallel ß sheet prefibrillar oligomers and ß barrel annular protofibrils that display generic epitopes that are recognized by polyclonal and monoclonal antibodies in a wide variety of amyloid forming proteins and peptides. We have raised 30 unique monoclonal antibodies that react with different epitopes and recognize different structures and aggregation states. This raises the question of whether these different amyloid structures have distinct functions in pathogenesis. Using these novel antibodies, we have discovered that unique types of amyloid deposits accumulate at specific times and locations during aging and disease such as intracellular amyloid which aggregates early inside neurons that ultimately degenerate and form the nidus of neuritic plaques. We are currently investigating these novel amyloid structures to determine their significance for disease processes and their mechanisms of pathogenesis. We are also characterizing endogenous human antibodies that are associated with protection against Alzheimer’s disease, infectious disease and cancer.

Founding Partner and CEO

Jake Glanville is an entrepreneur and computational immuno-engineer. He has developed multiple seminal methods in the fields of high-throughput antibody repertoire sequencing, repertoire decoding algorithms, single-cell TCR receptor & phenotype sequencing, and computationally guided antibody library engineering.

Assoc Dir Preclinical Discovery & Dev

Jochem has been at Bristol-Myers Squibb for 14 years in different roles of responsibility focused on biologics drug development. For the last 8 years he has been focused on building a group for pre-clinical immunogenicity risk assessment and mitigation. He received his training at the University of Groningen and the Dana Farber Cancer Institute.

Senior Director

Joel Goldstein received his PhD in molecular biology from the University of Medicine and Dentistry of New Jersey (UMDNJ) in 1991. He then did his postdoctoral work at Bristol-Myers Squibb (BMS) on antibody fusion proteins prior to joining Medarex in 1994. His role at Medarex was initially to develop bispecific antibodies and fusion proteins, which then evolved into developing antibody production platforms for manufacture. Joel moved back to BMS in 2009 where he continued to lead a team developing manufacturing cell lines for the company’s biologics programs. He then joined Celldex Therapeutics in 2014 to help manage R&D efforts, including establishing antibody engineering and bispecific antibody design strategies for the company’s pipeline.

Massachusetts Institute of Technology

McGovern Fellow/Principal Investigator

Jonathan Gootenberg, Ph.D. draws from fundamental microbiology to engineer new molecular tools. These tools, including the popular genome editing system CRISPR, allow for unprecedented manipulation and profiling of cellular states in the body, and have multiple applications in basic science, diagnostics, and therapeutics. Dr. Gootenberg uses gene editing, gene delivery, and cellular profiling methods to understand the changes that occur in the brain and other organs during aging, with the goal of generating new therapies for degenerative disease. Dr. Gootenberg earned his bachelor’s degree in mathematics and biological engineering at MIT and received his PhD in Systems Biology from Harvard University, during which he conducted research with Aviv Regev and Feng Zhang at the McGovern Institute and Broad Institute of MIT and Harvard. During his graduate work, Gootenberg focused on the development of molecular technologies for treating and sensing disease states, crossing disciplines by utilizing novel computational techniques, microbiology, biochemistry, and molecular biology to uncover new CRISPR tools, including Cas12 and Cas13. He and his co-authors developed Cas13 into a toolbox with uses in fundamental research, therapeutics, and diagnostics. These applications include RNA knockdown, imaging, the base editing platform REPAIR, and the sensitive, specific, and portable diagnostic platform SHERLOCK. He is one of the first members of the McGovern Institute Fellows program, which supports the transition to independent research for exceptional recent PhD graduates.

VP of Sales

Rick led the commercial launch of the Horizon system in 2017 and the Aura system in 2020 and currently supports their ongoing commercial development by assisting customers pre and post-purchase. Prior to this, Rick held similar positions at Unchained Labs, ForteBio, and Molecular Devices. Rick holds degrees from the University of Washington and the University of Maine and has scientific training in tumor immunology and cell biology.

Senior Director

Boris Gorovits is a Senior Director of the Bioanalytical lab at Pfizer. Boris earned Ph.D. in Enzymology from the Moscow State University and later completed postdoctoral research studies in Protein biophysics at the Medical Center, U of Texas at San Antonio, TX. In 2000 Boris joined Wyeth Research (later Pfizer Inc) to work as a bioanalytical group lead with a growing scope of responsibilities. Currently he leads the Bioanalytical group within Biomedicine Design department which is responsible for many aspects of the Regulated and Non-Regulated Bioanalytical support for the pan-Pfizer Biotherapeutic portfolio. Boris co-chairs Pfizer internal Immunogenicity Expert Working Group which is responsible for review of the biotherapeutic immunogenicity risk assessment and mitigation strategies. Recently Boris has been actively involved in industry discussions focusing on PK and immunogenicity assessment bioanalytical support of various modalities, including mAbs, bi-specific antibodies, antibody drug conjugates, gene therapy and CAR-T

Structural Genomincs Consortium

Dr.

Susanne Gräslund did her doctoral training in Biotechnology at the Royal Institute of Technology in Stockholm, Sweden. After her dissertation in 2002 she worked for three years at Biovitrum AB in the Target Expression & Purification section. In March 2005, Susanne joined the newly started Structural Genomics Consortium group in Stockholm, heading the Biotechnology team responsible for the generic protein production pipeline. She was then recruited to the SGC Toronto site as Principal Investigator for the Biotechnology team in September 2011. In 2015, SGC established a new lab at Karolinska Institutet in Stockholm where Dr. Gräslund is now leading a new team to generate recombinant antibodies for target validation and research purposes.

CEO

Larry is inventor of the AlivaMab® Mouse, CEO and founder of Ablexis, and founder and Chairman of the Board of AlivaMab Discovery Services. He has over a quarter century of experience in creating and using transgenic mouse platforms for antibody drug discovery and development. Previously at Abgenix (now Amgen), he was an inventor and user of the XenoMouse® technology, which has so far yielded seven approved antibody drugs.

Co-Founder and CCO

As ATUM’s Co-Founder and CCO, Dr. Gustafsson oversees most of the company's external communications. Prior to co-founding ATUM, Dr. Gustafsson led, managed and collaborated with key strategic teams at Maxygen Inc. Before Maxygen, Dr. Gustafsson worked as a scientist at Kosan Biosciences, a number of research, teaching, and post-doctoral positions at UCs Santa Cruz and San Francisco, and at University of Umeå. He received his Ph.D. in Molecular Biology/Biochemistry from the University of Umeå, Sweden.

Assoc Prof

Ben Hackel is an Associate Professor of Chemical Engineering and Materials Science at the University of Minnesota. He earned degrees in chemical engineering from the University of Wisconsin (B.S. 2003, advised by Eric Shusta) and MIT (Ph.D. 2009, advised by Dane Wittrup) and performed postdoctoral research in the radiology department at Stanford University (Sam Gambhir). Since its inception in 2011, the Hackel lab has applied protein engineering technologies to develop physiological molecular targeting agents for molecular diagnostics and targeted therapy, with a focus on oncology and infectious disease.

Memorial Sloan Kettering Cancer Center

Research Associate

Dr. Hamieh received his PhD from Rouen University in France. Currently, he is a research associate in Dr. Michel Sadelain lab at Memorial Sloan Kettering Cancer Center in New York. His work focuses on understanding the dynamics of CAR T cell anti-tumor response mainly mechanisms governing resistance to CAR T cell therapy and developing approaches to enhance engineered T cells against cancer.

Principal Scientist

Mei Han has worked in the biotech industry for 20 years after she obtained her M.S. from Dept. of Chemistry and Biochemistry, Montana State University. She is currently a Principal Scientist in the Pharmacokinetics & Drug Metabolism (PKDM) department at Amgen South San Francisco. Over the years, she has worked in different functional areas across Amgen, including Analytical Sciences, Protein Sciences, and PKDM. Her experience ranges from chromatographics (such as SEC, CEX, HIC, and RP-HPLC), electrophoresis (cIEF, CE-SDS, and CE-MS) and mass spectrometry analytical method development, inter- and intra-departmental method transfer, such as from Analytical Sciences to QC labs, involved in IND and BLA filing. She is also experienced in small- and middle-scale protein purification. She implemented Capillary Electrophoresis (CE) techniques into Protein Science and PKDM departments, developed an automated immunoaffinity capture (IA)-CE-MS intact mass analysis biotransformation workflow in PKDM department to support multiple pipeline projects ranging from antibodies, fusion proteins, and antibody conjugates in vitro and in vivo, as well as other characterization techniques. Currently ,she leads the large-molecule ADME team within PKDM, interacting with Project Team Representatives to support projects and serve as resource for protein characterization, analytical method development, troubleshooting, and experiment planning. Over the past 20 years, she has been involved in Beckman/Sciex’s CE-SDS Analysis Kit development, providing much input for CE-related instrument development for multiple vendors, such as PA800 Plus, iCE280, CE Infinite, etc. Currently, she serves as a CE Pharm Committee member and Associate Director for CASSS.

Associate Director, Methods Development

Michael Hantman, Associate Director of Methods Development and Validation received his Ph.D. from Temple University School of Medicine working on genetic mapping and pathogenicity of Streptococcus mutans, the main cause of dental caries.  Postdoctoral fellowships at Harvard Medical School, MGH, and the University of Washington focused on vaccine development and host-pathogen interactions, using recombinant, attenuated salmonella strains expressing heterologous genes to stimulate immune pathways.  

Prof Molecular Immunology

Claire’s interest in complement dates back to her undergraduate days when she was inspired by teaching on innate immunity and was intrigued by the ability of a protein-based, soluble system to punch holes in target cells! She obtained her PhD at Cambridge University, UK, and moved to Cardiff, UK, in 1993 as a postdoctoral scientist studying the biochemistry and function of complement proteins in humans and other species. Funding from the Wellcome Trust enabled her to establish a group focused on structure–function relationships in complement activators and regulators with a particular interest in the mechanisms underlying complement dysregulation and disease. Recent work includes functional characterization of complement protein variants/mutants associated with diseases such as age-related macular degeneration (AMD), atypical haemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G). This work has led to the concept of the 'complotype' -the influence of complement genetic makeup on inflammation & infection. In 2013, she was appointed as Head of Complement Drug Dicovery at GlaxoSmithKline in the ImmunoInflammation Therapy Area and gained invaluable insight into the process of target and indication validation and drug discovery; she joined Newcastle University in 2016 to further her work in translational research and experimental medicine. With experience both in academia and the pharmaceutical industry, her current research is focussed on therapeutic approaches for modulation or inhibition of the complement cascade, particularly on strategies to target or ‘home’ therapy specifically to disease sites.

Sangamo Therapeutics

Scientist II

Asa Hatami is currently a scientist at Sangamo Therapeutics, focusing on the use of zinc finger protein transcription factors to regulate gene expression as a therapeutic approach for central nervous system disorders. Previously, Asa’s postdoctoral training was on the development of small molecules to increase alpha-cleavage of amyloid precursor protein as a therapeutic strategy for the treatment of Alzheimer’s disease; investigation of neuronal exosome-associated molecules as biomarkers of disease state and progression in neurological disorders; investigation of the propagation and toxicity of structurally defined alpha-synuclein fibril polymorphs in vitro and in vivo; and the use of preclinical models of Parkinson’s disease, Huntington’s disease, and traumatic brain injury to investigate a broad range of therapeutic strategies for neurodegenerative disorders. Asa holds a Ph.D. from UC Irvine’s Department of Molecular Biology and Biochemistry.

Associate Director

Laura Hay earned her Ph.D. in Molecular Biology and Biochemistry at Purdue University, before joining the National Cancer Institute at the NIH as a postdoctoral fellow. After 3 years at the NIH studying carcinogen DNA interactions, Laura joined PPD as a Research Scientist in 2004 in the Immunochemistry Research and Development department. Dr. Hay began overseeing method development and validation projects utilizing numerous ligand binding assay platforms for pharmacokinetic and immunogenicity assays on behalf of a variety of pharmaceutical and biotech companies. In 2016, she transitioned to the Immunochemistry Assay Services department, where her scientific background and managerial skills were joined to lead a large group of scientists in conducting method validations and subsequent sample analysis projects to support various novel biotherapeutics. Today, Dr. Hay is Associate Director in Immunochemistry Assay Services, and continues to oversee both scientific and business aspects of nonclinical and clinical studies.

Lawrence Livermore Natl Lab

Biomedical Scientist

Wei He is a Biomedical Scientist at the Lawrence Livermore National Lab in California, USA. His research focuses on the development of new biotechnology to study membrane protein, cancer biology, and vaccine development.

Product Manager

No bio available.

Research Scientist

Adam Hejmowski is a Research Scientist working in the Gene Therapy group on chromatographic processes. He earned degrees in Biotechnology (B.S.) and Chemistry (B.S.), followed by a Masters of Science in Cellular and Molecular Biology from the University of New Haven. Previously he worked for 4 years at Abcam Inc, formerly AxioMx Inc, in Branford, CT working on monoclonal antibody development and characterization using phage display technologies and automated equipment.

Sr Tech Program Mgr

Dawn holds a PhD in Genetics and Genomic Sciences from University of Alabama at Birmingham. Prior to joining SCB, she worked as a post-doctoral fellow at the National Institutes of Health in the National Eye Institute performing stem cell research developing retinal organoids for testing and therapeutic purposes from stem cells. Currently she works as the senior technical program manager for the Standards Coordinating Body. Dawn works to oversee all technical projects to coordinate and facilitate the development of standards for regenerative medicine.

Graduate Student/ PhD Candidate

Natalia Herrera did her undergraduate education studying Biochemistry at the University of California, Santa Cruz. She then went on to do her PhD. in the laboratory of Dr. Steven Almo, at Albert Einstein College of Medicine, where she studies proteins in the immunoglobin and TNFR superfamilies, and immunotherapeutics.

Co-Found and Head, Business Development

Kevin Heyries holds a PhD in biochemistry (Uni. of Lyon) where he developed microfluidics for antibody analysis. During his postdoctoral work (Uni. of British Columbia), he developed high throughput microfluidics systems for digital PCR and single-cell genomics. Dr. Heyries was instrumental in the development of AbCellera’s technology, where he is now leading business development and strategy.

Head of Immunosafety

Tim recently joined Roche as Head of Immunosafety to focus on quantitative assessment of immunosafety risks. Tim previously lead Pfizer's Immunogenicity sciences team, where he contributed to better by design processes for minimizing immunogenicity risk, and spearheaded the industry's efforts to predict immunogenicity through quantitative systems pharmacology modeling of immune responses to biotherapeutics.

VP Drug Discovery

Oliver Hill joined Apogenix in March 2006. He is an expert for protein engineering and expression. Prior to his position at Apogenix, he headed the protein expression and purification group at Graffinity Pharmaceutical Design GmbH (Heidelberg, Germany) from 1999 to 2006. At Graffinity Oliver Hill was responsible for delivering a broad spectrum of target proteins for screening on a chemical microarray platform. His work in former, academic R&D positions at the Lower Saxony Institute for Peptide Research (Hannover, Germany; 1992-1996) and the Institute for Molecular Biotechnology (Jena, Germany; 1997-1998) included gene hunting, protein engineering and the development of recombinant phage display technologies. Mr Hill studied biology at the University of Hannover where he also received his PhD from the Department of Chemistry in 1997.

National Cancer Institute, NIH

Chief

Dr. Ho is a Senior Investigator, the Deputy Chief of the Laboratory of Molecular Biology, the Head of the Antibody Therapy Section, and the Director of the Antibody Engineering Program at the National Cancer Institute (NCI). He received his Ph.D. from the University of Illinois at Urbana-Champaign, where he designed anti-idiotypic antibodies as cocaine antagonists. He completed a postdoctoral fellowship with Ira Pastan at the NIH, where he engineered immunotoxins targeting CD22, and mesothelin for the treatment of B cell leukemias and mesothelioma. Dr. Ho's laboratory at the NCI has been studying the biology of cancer driven by cell surface proteins, such as glypicans (e.g. GPC3, GPC2) as a new family of tumor antigens, in broad scientific fields of molecular and cellular biology with a focus on ligand/receptor interactions, Wnt/Yap oncogenic signaling, antibody/nanobody protein engineering, structure biology, functional genomics analysis, and cancer immunotherapy.

Lab Head, Mass Spectrometry, Protein Therapeutics

Dr. Soraya Hölper joined Sanofi in 2017 as a Lab Head for Mass Spectrometry and works on developability and analysis of complex therapeutic antibodies. Before joining Sanofi, she helped set up the mass spectrometry platform at the Institute of Biochemistry in Frankfurt. Soraya holds a diploma degree in biochemistry from the Goethe University of Frankfurt am Main and a Ph.D. from the Max-Planck-Institute for Heart and Lung Research in Bad Nauheim.

Senior Vice President, R&D Governance Chair, and Therapeutic Area (TA) Head

Dr. Axel Hoos is Senior Vice President, R&D Governance Chair, and Therapeutic Area (TA) Head for Oncology at GlaxoSmithKline Pharmaceuticals (GSK). He is responsible for discovery and development in Oncology with focus on immuno-oncology, epigenetics, cell therapies and genetic medicine. As R&D governance chair he oversees technical and funding review committees. He returned GSK to Oncology after the divestment of its marketed medicines to Novartis in 2015 and is responsible for GSK's Oncology portfolio focusing on innovative medicines to deliver transformational benefit to patients. Recent portfolio expansion included the acquisition of Tesaro, a co-development partnership with Merck-Serono, and the in-licensing of the first cell therapy active in solid tumors from Adaptimmune. Dr. Hoos also serves as Chairman of the Board of Trustees of the Sabin Vaccine Institute (SVI), a Global Health organization, Director on the Board of Imugene, a biotech company, Co-Director of the Cancer Immunotherapy Consortium (CIC) and Scientific Advisory Board Member of the Cancer Research Institute (CRI). His efforts focus on novel therapies for life-threatening diseases, scientific and technical innovation, and business and scientific collaboration. Through his leadership a paradigm for the development of cancer immunotherapies has been defined, which helped launch the field of Immuno-Oncology (Nat. Rev. Drug Discovery 2016, 15(4):, 235-47). Previously, Dr. Hoos was the Global Medical Lead in Immunology/Oncology at Bristol-Myers Squibb (BMS) where he developed Yervoy (Ipilimumab), the first life-extending therapy and the first checkpoint inhibitor drug in Immuno-Oncology. The discovery of ipilimumab’s scientific mechanism was honored with the Nobel prize for Physiology or Medicine to Dr. James Allison in 2018. Before BMS, Dr. Hoos was Senior Director of Clinical Development at Agenus Bio (previously Antigenics), a biotech company. Dr. Hoos holds an MD from Ruprecht-Karls-University and a PhD in molecular oncology from the German Cancer Research Center (DKFZ) both in Heidelberg, Germany. He trained in surgery at the Technical University in Munich and further in surgery, molecular pathology and tumor immunology at Memorial Sloan-Kettering Cancer Center in New York City. He is an alumnus of the Program for Leadership Development at Harvard Business School.

Sr Scientist

Xiaoqing Hua is a Sr. Scientist in analytical method development group at Merck. Her primary focus is on analytics of therapeutic proteins with LC based separation methods, as well as capillary electrophoresis methods such as icIEF and CE-SDS. Before joining Merck, she did internship in Celgene, biologics downstream and analytical process development group, working on analytical method development, process characterization support, and process development support. She has a PhD in Chemical and Biomolecular Engineering from Johns Hopkins University.

Chief Scientist and CSO

Dr Peter Hudson, FTSE, BSc Hons (Adelaide, Australia), PhD (MRC-LMB, Cambridge, UK). Peter is CSO of Avipep P/L (Melbourne) and Avipep Therapeutics P/L (Boston) and recently led a large oncology consortium to complete the first Phase 1 clinical trial of a novel engineered antibody (AvibodyTM) targeting prostate and ovarian cancer. Peter has co-founded four Australian biotech companies Evogenix Pty Ltd (2001), Avipep Pty Ltd (2005), CarTherics Pty Ltd (2015) and IsoClide Med Pty Ltd (2017). Peter is currently an Adjunct Professor at the University of Queensland and was formerly a Chief Research Scientist and Program leader in CSIRO (1990-2008) and Deputy CEO and Scientific Director of the CRC for Diagnostics (1995-2007). He was also Director for Business Development in the AIBL Alzheimer’s Disease consortium and the CRC for Mental Health (2009-2012). Peter was elected to the Australian ATSE Academy and has been awarded the AMRAD Biotechnology and CSIRO Chairman’s Medals.

Assistant Professor

Meredith Jackrel graduated from the College of New Jersey with a BS in Chemistry in 2004 and received her Ph.D. in Chemistry from Yale University in 2010.In 2010, Meredith joined James Shorter’s laboratory in the Department of Biochemistry and Biophysics at the University of Pennsylvania as a postdoctoral fellow. In 2017, Meredith became an Assistant Professor of Chemistry at Washington University in St. Louis. There her group studies protein misfolding and approaches to reverse misfolding.

Director

Darshana Jani is Head of Global Bioanalytical Sciences in support of Biologics at Agenus Inc., located in MA. Prior to that, she served as Scientific Associate Director at Pfizer, Cambridge, MA, USA, where her role was to serve as scientific and technical lead for both CROs and internal teams for development, validation, and application of bioanalytical assays to comply with scientific and regulatory requirements. She has over 25 years of experience in supporting preclinical to clinical studies holding positions with Sanoffi, MedImmune, Biogen, and Pfizer. She has risen from the ranks, at the outset developing and applying bio analytical methods, while assuming numerous responsibilities germane to regulatory compliance of the validation and application of group procedure. She has also guided bioanalytical lab groups held responsible for overseeing any and all phases of drug recovery and development; a task which incorporated product characterization, potency determination, immunogenicity testing, as well as surrogate biomarker assay development, validation, and sample testing. Lastly, she has published several recommendation white papers with industry, academic, and regulatory peers in the area of biomarkers, as well as immunogenicity.

Commissioners Fellow & Biologist

Dr. Jankowski is a research reviewer with the US Food and Drug Administration in the Office of Tissues and Advanced Therapies. He is part of an active research laboratory and his research interests lie in the regulatory-science associated with the licensure of the next generation of therapeutic proteins. A key focus of his research activities has been to understand the immune response to protein therapeutics, which can significantly affect the efficacy and safety of these drugs. He uses a combination of computational, in vitro and ex vivo approaches in his work. Dr. Jankowski received his Ph.D. from Rutgers University, NJ and was subsequently selected for the highly competitive Commissioner’s Fellowship program at the FDA. His research has been published in high impact journals such as Nature and Nature Chemical Biology.

Prof

Martin F Jarrold obtained his undergraduate and graduate degrees from the University of Warwick in England, and then went to the University of California, Santa Barbara as a NATO Postdoctoral Fellow. After several years in California, he joined the Physics Research Division of AT&T Bell Laboratories in Murray Hill, New Jersey. In 1992, he moved to Northwestern University to become a Professor in the Chemistry Department. While at Northwestern he performed pioneering work on ion mobility mass spectrometry. In 2002 he moved to Indiana University as Professor and Robert and Marjorie Mann Chair. His recent work at IU has focused on developing charge detection mass spectrometry.

Dir Predictive & Clinical Immunogenicity

Dr. Vibha Jawa is currently a Director, Predictive and Clinical Immunogenicity group within Preclinical Development at Merck. She is responsible for developing a strategy and provides oversight and management of scientific programs for discovery, development and optimization of biologics and vaccines. In this role, she is partnering with discovery and development groups to design better molecules. Dr Jawa received her bachelors in Biochemistry (1991) from Delhi University and her doctorate in Biochemistry/Immunology (1998) from All India Institute of Medical Sciences, New Delhi, India with a thesis work studying the immune mechanisms behind autoimmune diseases followed by a postdoctoral fellowship at University of Pennsylvania on monitoring the immune response to viral vectors. She continued to work in the field of gene therapy company evaluating viral vectors for hemophilia therapy in the Bay area followed by City of Hope Cancer Centre Stem Cell and Gene Therapy group and at Amgen from 2003-2016. Her current research interests include evaluating immune response biomarkers for early drug development and efficacy, immunogenicity prediction using in silico, in vitro and in vivo technologies, modeling impact of immunogenicity on PK and PD and their application to a systems based approach, antigen processing and presentation and the role of T cells in immune response to drug products. Vibha is a member of multiple professional organizations like American Association of Pharmaceutical Scientists (AAPS), American Association of Immunology (AAI) , European Immunogenicity Platform and Federation of Clinical Immunology Society (FOCIS). Within AAPS, Vibha has been actively involved as a Steering Committee member of the Therapeutic Protein Immunogenicity Focus Group (TPIFG) and is currently leading the Immunogenicity Risk Assessment and Mitigation Working Group (IRAM). She is also a co-lead of the Industry Innovation and Quality consortium for Cell/viral/gene therapies. Dr. Jawa also serves as a manuscript reviewer for The AAPS Journal , Clinical Experimental Immunology and J.Pharm Sci Journal. Dr. Jawa has published over 50 papers and her articles in the Nature Genetics, Annals of Hematology and Clinical Immunology journals have been cited over 2500 times. She is the recipient of the 2015 Ebert Prize from the American Pharmacists Association for her work on assessing risk of critical quality attributes in a humanized mouse model system.

Associate Research Director

Saurabh Joshi is the head of antibody discovery and cell-line development at Syngene. In a career spanning close to 20 years, he has worked on a wide variety of scientific challenges across therapeutic and tool antibody discovery, bio-therapeutic cell line generation, analytical tools and assay development for large molecules. Saurabh holds a PhD as well as M.Sc. from the University of Mumbai

Sr Scientist

Lynn Kamen is a Senior Scientist in the BioAnalytical Sciences department at Genentech. She earned her Ph.D. in Immunology at the University of Michigan and completed a postdoctoral fellowship in immunology at the University of California San Francisco. Following her postdoctoral fellowship, Lynn transitioned into industry working in early drug discovery of both small and large molecules at several biotech companies including Portola Pharmaceuticals and Alector. Since joining Genentech, Lynn has supported the in vitro biological characterization of large molecules and lead the development of immunogenicity assays including ADA, NAb and immunogenicity risk ranking assays. She is co-lead of the AAPS NAber working group and member of the AAPS NAb drug tolerance sub-team.

Senior Scientist

Dr. Manzhu Kang received her Ph. D. from the University of California Los Angeles, with a dissertation focusing on the impact of combinatorial therapy on the evolution of drug resistance. Dr. Kang is a senior scientist of antibody research group at GenScript ProBio. She is in charge of the single B cell screening platform for antibody drug discovery. 

Director Protein Products & Assays

Dennis Karthaus received his master`s degree in biotechnology from the Univ. of Applied Sciences in Bremerhaven. During his thesis he worked on the development of protein purification platforms and in cell line development. In 2012, Dennis Karthaus joined IBA Lifesciences. He's leading the department for protein purification & assays and is responsible for the development of products & technologies for protein expression, purification and analysis.

Natl Research Council Canada

Sr Research Officer

John received a B.Sc. in Chemistry and Biochemistry from the National University of Ireland (Galway). He worked for a number of years as a product development chemist in Elan Pharmaceuticals before deciding to pursue higher academic studies in Canada. John holds a Ph.D in Analytical Chemistry from Dalhousie University. He was an NSERC industrial postdoctoral fellow at Merck Frosst in Montreal before joining the National Research Council of Canada (NRC) in 1997 as a Research Associate. John is now a Senior Research Officer at NRC’s Human Health Therapeutics (HHT) Research Centre in Ottawa, Ontario. His research focuses primarily on the mass spectrometry analysis of proteins in support of HHT’s biotherapeutics and vaccine development initiatives.

Dyno Therapeutics

CEO & Co Founder

Eric Kelsic, PhD, is CEO and co-founder of Dyno Therapeutics, a VC-backed biotech located in Cambridge, Massachusetts. Dyno is leading a machine learning revolution to develop enhanced capsid proteins that enable new gene and genome editing therapies. Eric co-developed the technology underlying Dyno’s machine-guided protein engineering platform in George Church’s lab at the Wyss Institute of Harvard Medical School. He holds a PhD in Systems Biology from Harvard University and a BS in Physics from Caltech.

Asst Prof of Medicine & Oncology & Sr Consultant

No bio available.

CSO

Bruce received his Ph.D. in biochemistry and pharmacology from Tufts University School of Medicine and his B.S. in Chemistry from Washington University in St Louis. He is a co-inventor on more than 35 U.S. patents and patent applications, and he has a co-authored more than 55 scientific articles. Bruce brings to IGM more than thirty-five years of research, development and management experience in large and small biotechnology companies, including his extensive experience in many phases of early stage drug discovery and development. This experience spans target selection and discovery, in vitro biochemistry, in vivo efficacy models and all other aspects of the pre-clinical development of antibodies and proteins as therapeutic agents.

Senior Director of Biologics

Shireen S. Khan, PhD, Senior Director of Biologics at ChemPartner in South San Francisco, leads a Biologics group expanding ChemPartner’s capabilities into single B cell cloning on the Beacon platform. She also leads multiple therapeutic antibody discovery programs for biotech and pharmaceutical companies. 

Assoc Prof

Philip M. Kim is a Professor at Donnelly Centre at the University of Toronto. He leads a research laboratory that integrates machine learning, physics-based modeling and wet/experimental methods for engineering of biologics. He is a Co-founder of Resolute Bio, a drug development startup company. He authored over 70 publications, 7 invention disclosures and 3 patent applications. Before to setting up his lab in 2009, he was a postdoctoral fellow at Yale University where he pioneered structural analyses of protein interactions networks and an associate with McKinsey & Co. He holds a Ph.D. from the Artificial Intelligence Laboratory and Department of Chemistry at the Massachusetts Institute of Technology and a B.S. in Biochemistry and Physics from the University of Tuebingen.

Deputy Associate Director for Research, Office of Tissues and Advanced Therapies

Chava Kimchi-Sarfaty currently leads a group at the FDA within the Division of Plasma Protein Therapeutics, Office of Tissues and Advanced Therapies (OTAT) that investigates various blood coagulation factors with a specific focus on the genetic determinants of coagulation factor biosynthesis and structure. She is also the Acting Deputy Associate Director for Research of the Office. She reviews and chairs pre-INDs, INDs and BLAs for recombinant proteins and plasma derivatives products such as von Willebrand factor, ADAMTS13, factor VIII, FIX, thrombin and fibrinogen.

Sr Scientist

JT received his PhD in Chemical Engineering from the University of California Berkeley where he developed novel protein engineering strategies for viral gene therapy. He then completed a post-doc with Jim Wells at the University of California San Francisco where he developed a novel structure-based design platform to generate phospho-specific antibodies. At Genentech, he works in the collaborative environment to discover novel biology and transformative drugs. Our goal is to advance new therapies to patients by tackling challenging targets and engineering around drug delivery barriers.

Instructor

No bio available.

New York University School of Medicine

Prof & Principal Investigator

Shohei Koide, Ph.D., is a synthetic protein scientist. His research integrates structure-guided design and directed evolution to create highly functional, but still simple, proteins. He is the inventor of the FN3 Monobody technology, and he has made important contributions to synthetic antibody technologies and to the application of synthetic binding proteins to biology, chemistry, and medicine. His current research focuses on the discovery of cancer therapeutics and on establishing strategies to control "undruggable" targets, and lately on COVID-19. Previously, he was Professor at University of Chicago and at the University of Rochester School of Medicine and Dentistry.

Sr Research Advisor

Helen Kotanides is a Senior Research Advisor at Loxo Oncology at Lilly. She received her Ph.D. degree in Molecular Biology and Biochemistry from Stony Brook University in New York. Helen has over 20 years of cancer research experience at Eli Lilly and ImClone Systems, both of which have focused on the development of antibody therapeutics.

Head

PhD. Head of Bioassay Department at Biocad, Russian Leading Innovative Biotechnology Company. The department is responsible for selection the bioassay strategies and development, validation and transfer bioassays including potency assays in support of drug development pipeline.

Graduate Student

Dennis Krieg is a pharmacist by training and Ph.D. student in the research group of Prof. Dr. Gerhard Winter at the Ludwig-Maximilians-University Munich, Germany. In his thesis, Dennis focuses on different aspects of protein co-formulations. His work includes the analytical characterization, formulation development, stability testing and interaction studies of co-formulations for therapeutically relevant cytokines, enzymes and antibodies.

Associate Professor

Andrew Kruse an Associate Professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. Prior to joining the faculty at Harvard, he completed doctoral training with Brian Kobilka at Stanford University where he studied neurotransmitter receptor structure and pharmacology. Research in the Kruse lab focuses on structure and mechanisms of transmembrane signaling proteins, with a particular emphasis on the development and application of antibody fragments as tools to study signaling receptors. Dr. Kruse is the recipient of a Smith Family Award for Excellence in Biomedical Research, a Klingenstein-Simons Fellowship, a Vallee scholar award, and an NIH Director’s Early Independence Award.

Co-founder and Managing Director

Dr. Prabuddha Kundu is a Co-founder and Managing Director at Premas Biotech. He has 20 years of experience in various roles and capacities. He holds a Ph.D. in Biomedical Engineering from Indian Institute of Technology, Mumbai, and has interests in protein engineering, bio-process development, lean transformation, and new technologies. He has more than 22 publications and 10 patents. 

Arizona State University BioDesign Institute

Executive Director

Joshua LaBaer is one of the nation’s foremost investigators in the rapidly expanding field of personalized diagnostics. His efforts focus on the discovery and validation of biomarkers — unique molecular fingerprints of disease — which can provide early warning for those at risk of major illnesses, including cancer and diabetes. Formerly founder and director of the Harvard Institute of Proteomics, LaBaer was recruited to ASU’s Biodesign Institute as the first Piper Chair in Personalized Medicine in 2009. The Virginia G. Piper Center for Personalized Diagnostics (VGPCPD) has a highly multidisciplinary staff of molecular biologists, cell biologists, biochemists, software engineers, database specialists, bioinformaticists, biostatisticians, and automation engineers. VGPCPD applies open reading frame clones to the high throughput (HT) study of protein function. In addition, his group invented a novel protein microarray technology, Nucleic Acid Programmable Protein Array, which has been used widely for biomedical research, including the recent discovery of a panel of 28 autoantibody biomarkers that may aid the early diagnosis of breast cancer. LaBaer earned his medical degree and a doctorate in biochemistry and biophysics, from the University of California, San Francisco. He completed his medical residency at the Brigham and Women’s Hospital and a clinical fellowship in oncology at the Dana-Farber Cancer Institute, both in Boston. He has contributed more than 150 original research publications, reviews and chapters. LaBaer is an associate editor of the Journal of Proteome Research, a recent member of the National Cancer Institute’s Board of Scientific Advisors, Chair of the Early Detection Research Network Steering Committee and recent president of the U.S. Human Proteome Organization.

European Research Institute for the Biology of Ageing

Group Leader

Dr. John LaCava is an NIH-funded investigator, Research Faculty member at The Rockefeller University, and a Group Leader at the European Research Institute for the Biology of Ageing. He focusses on the development of affinity proteomic methods to capture and characterize endogenous macromolecules – lately pursuing molecular pathophysiology and associated perturbations in protein interaction networks.

Associate Professor

My doctoral work focused on structural studies of amyloid-related proteins using X-ray crystallography that received the biochemistry distinguished dissertation award. In my doctoral research, I used pioneering micro X-ray crystallography along with a combination of techniques including the modification, design, expression, and purification of proteins/peptides, as well as structural and computational modeling. As a Nicholas Kurti Junior Research Fellow of Brasenose College in the laboratory of Professor Dame Carol V. Robinson at the University of Oxford, I pioneered novel ion mobility mass spectrometry approaches and methods to study membrane proteins and their interactions with lipid/drug molecules. Since starting my own group in 2014, we have continued to pioneer native mass spectrometry approaches to determine lipid binding thermodynamics and cooperativity, allostery within protein-protein, protein-lipid interactions, and heterogenous lipid binding events to membrane proteins.

Sr Staff Scientist

Dr. Vicky Lai is currently a Senior Staff Scientist in Bioanalytical Sciences Department at Regeneron. In her current role, she serves as the subject matter expert in regulated bioanalysis and immunogenicity of biotherapeutic programs in immunology and inflammation therapeutic area. Dr. Lai has supported more than 10 biotherapeutic programs from early clinical phase to post marketing stage and has been involved in multiple regulatory submissions of biotherapeutic marketing approval. Her interests pertain to immunogenicity of biotherapeutics from risk assessment to clinical impact on PK/PD. Prior to Regeneron, she served as Research Investigator at Novartis and Principal Scientist at Valeant Pharmaceuticals International, where her group was responsible for anti-viral drug development from discovery to late phase clinical development. She earned her doctoral degree from the Chinese University of Hong Kong and completed her postdoctoral training at Merck (formerly Schering Plough Research Institute).

Albert Einstein College of Medicine

Professor

Jonathan Lai is Professor of Biochemistry at the Albert Einstein College of Medicine in the Bronx, NY. Dr. Lai received his undergraduate training in Biochemistry at Queen’s University in Kingston, Ontario, Canada, then obtained his PhD in Chemistry and Biophysics at the University of Wisconsin, Madison in 2004. From 2004-2007, he was Helen Hay Whitney Post-Doctoral Fellow in Biological Chemistry at Harvard Medical School. He began his independent lab at the Albert Einstein College of Medicine in 2007. His group has broad interests in peptide, protein, and antibody engineering with application of these methods to discovery of new immunotherapies and vaccines.

Executive Vice President & CSO

Dr. Lamb is scientific co-founder, Executive Vice President, and Chief Scientific Officer of Incysus Therapeutics. As a transplant immunologist with 27 years’ experience in clinical-translational immunotherapy research, he is responsible for first describing the association between relapse-free survival and homeostatic T cell recovery in patients with high-risk leukemia following haploidentical bone marrow transplant. While at the University of Alabama at Birmingham, Dr. Lamb developed the scientific support for chemotherapy resistant T cell-based immunotherapy for high-grade brain tumors that that has become the foundation of our clinical programs. Dr. Lamb currently leads clinical, translational, and manufacturing strategy and operations for Incysus Therapeutics.

Consultant & Scientific Advisor

Dr. Lambert graduated from Christ’s College, University of Cambridge (England, UK), with a degree in Natural Sciences in 1972. He then went on to earn a Ph.D. in Biochemistry (1976) from the University of Cambridge, working on enzyme structures under the supervision of Professor Richard N. Perham. Dr Lambert’s postdoctoral training was at the University of California, Davis, working on ribosome structure in the laboratory of Dr Robert R. Traut (1976-1980), and at the University of Glasgow, Scotland working on the arom multienzyme complex in the laboratory of Dr John R. Coggins (1980-1982). In 1982, Dr. Lambert joined the Dana-Farber Cancer Institute, Harvard Medical School, working on the ImmunoGen-funded programs to develop antibody-drug conjugates (ADCs) and immunotoxins as anti-cancer therapeutics. Dr. Lambert joined ImmunoGen in 1987 when the company established independent research laboratories in Cambridge, Massachusetts. After working in a variety of roles at the company, Dr. Lambert served as Chief Scientific Officer from 2008 until 2015. In 2016, he became a Distinguished Research Fellow at the company until his retirement at the end of 2017. He served on the Executive Committee of the company as Executive Vice President, Research, from 2008 until 2016, followed by a year (2017) on the Executive Committee in an Emeritus capacity. During Dr Lambert’s tenure in leadership roles at ImmunoGen, the company invented the ADC technology that resulted in the Genentech/Roche drug, Kadcyla® (approved in 2013 for treating HER2+ breast cancer), as well as numerous other ADCs taken into clinical development. One of these is ImmunoGen’s promising drug candidate, mirvetuximab soravtansine, an ADC currently in a phase 3 trial for the treatment of platinum-resistant ovarian cancer. Dr Lambert is the author/co-author of over 120 peer-reviewed scientific publications. In 2016, Dr Lambert was elected as a Fellow of the American Institute for Medical and Biological Engineering (AIMBE). In 2018, he was appointed as an Honorary Professor of Queen’s University, Belfast, Northern Ireland, UK.

Marketing Manager

No bio available.

Marketing Manager

No bio available.

VP

Dr. Lang is Vice President of Biologics at Aragen, leading antibody discovery and optimization, cell line development and protein production. Dr. Lang previously held leadership positions Genentech, Janssen and Johnson & Johnson. Dr. Lang received his Ph.D. in Molecular Microbiology from State University of New York Stony Brook.

President

David Lansky has been practicing statistics on bioassays (and other non-clinical applications in Pharma) for 30 years. This includes 10 years at Searle/Monsanto/Pharmacia and 16 years as the owner of Precision Bioassay, Inc. David has been and is still an active participant in the work to revise the USP bioassay chapters. His education includes a year of Electrical and Computer Engineering (University of Michigan), a BS in Botany (San Francisco State), an MS in Entomology (Cornell) and finally both an MS and Ph.D. in Biometry (both Cornell).

Donna & Benjamin M Rosen Chair

Steven M. Larson, MD., FACNM, FACR is currently the Donna and Benjamin M. Rosen Chair; Attending, Molecular Imaging and Therapy Service, Department of Radiology; Co-Leader, Imaging and Radiation Sciences, Member, Laboratory Head, Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center. Dr. Larson’s primary expertise is in radiolabeled drug development and radiopharmacology of diagnostic imaging and therapy in oncology using small molecules and monoclonal antibodies. Dual-boarded in nuclear medicine and internal medicine, his clinical skills center on oncology, cancer immunology, and clinical thyroid cancer. Dr. Larson has extensive experience as an advisor to public and private institutions, having served, among other appointments, as a member of what is now the MEDI grant review committee of NIH, the DOE Office of Science Advisory Committee, and the American Board of Nuclear Medicine, and as Chair of the Radiopharmaceutical Advisory Committee of the USFDA, Co-Chair of the National Research Council of the NAS Committee on Molybdenum-99 production with non-enriched Uranium 235, Chair of the Molecular Imaging Committee of RSNA, and Co-Chair of the Clinical Imaging Steering Committee of the NCI, and Chair of the NIH Clinical “Impact” Study Section, as well as a member of the Academy of Medicine. Dr. Larson has received numerous awards for excellence in nuclear medicine, including the Hevesy Award, Cassen Prize, Wiley Prize (US FDA), and the Saul Hertz Award of the Society of Nuclear Medicine USA. He is a member of the National Academy of Medicine of the National Academies of Science, USA

Ben Gurion Univ of the Negev

Prof Nuclear Engineering & Dir

Professor Laster received her B.S. in biology from Stern College for Women, New York, NY and her graduate studies were carried out at Memorial/Sloan Kettering, New York NY, where her major was Diagnostic Cytology. Her Ph.D. studies in experimental pathology and radiation biology were carried out at the State University of New York at Stony Brook, Stony Brook, NY and the Union Institute, Cincinnati, Ohio. Her thesis was on “Binary Systems for the Improvement of Cancer Radiotherapy” and her thesis advisor was Victor P. Bond, M.D., Ph.D. Before joining the faculty of Ben Gurion University, Professor Laster was a scientist in the Medical Department of Brookhaven National Laboratory in Upton, N.Y. and an Assistant Professor in the Department of Radiation Oncology in the School of Medicine at the State University of New York at Stony Brook. She served as a visiting professor in the Department of Radiation Physics at the University of Lund, Lund, Sweden, and in the Social Dimensions of Science, Project WISE, at the State University of New York at Stony Brook, Stony Brook, N.Y.

Dir & Sr Scientist

Greg Lazar received his BS in Molecular & Cell Biology and Chemistry from Penn State, his PhD in Molecular & Cell Biology from the University of California at Berkeley, and did postdoctoral research at the University of Cambridge, UK. Previously he led research groups at Eli Lilly and Xencor. Currently he is Director and Senior Scientist in Antibody Engineering at Genentech where he oversees antibody technology platforms, high-throughput protein production, and infrastructure for automation, software, and informatics. His research group is focused on the development of novel antibody technologies to enable next generation therapeutics to treat unmet medical needs in oncology and neuroscience.

Asst Prof

Jiwon Lee is Ralph and Marjorie Crump Assistant Professor in Thayer School of Engineering at Dartmouth College. He received his BA in Molecular and Cell Biology from the University of California, Berkeley, and his PhD degree in Chemical Engineering at the University of Texas at Austin. His research group is interested in developing cutting-edge technologies for immune profiling to understand how antibody repertoires impact health and disease in the context of infectious disease, autoimmunity, and cancer, then applying this knowledge as a guide for engineering next-generation prophylactics and therapeutics.

Postdoctoral Research Fellow

Dr. Elissa Leonard attended Harvery Mudd College, where she received her B.S. in Biomolecular Systems and Design, and developed novel bioreactor designs for corneal tissue engineering with Dr. Elizabeth Orwin. She earned her Ph.D. at the University of Texas at Austin, where her research focus shifted to engineering therapeutically relevant autoimmune T cell receptors under the supervision of Dr. Jennifer Maynard. Currently, Dr. Leonard is a Postdoctoral Fellow at Johns Hopkins University, where she has continued research in protein and immune engineering with Dr. Jamie Spangler. Currently, her work focuses on engineering antibody-cytokine fusion proteins that can shift the immune balance and promote anti-tumor or pathogen-clearing immune activity. She is also revisiting her regenerative engineering roots by engineering of growth hormones for applications in osteogenesis.

VP

Nancy Levin joined Triphase in 2015 with more than 20 years’ experience in the biotechnology industry, and technical expertise in clinical and translational pharmacology and nonclinical development. Nancy was Vice President of Therapeutics Product Design Group at Intrexon Corporation (2013-2014), where she oversaw the conception and development of novel therapeutic partnering opportunities enabled by Intrexon’s proprietary cell- and DNA-based technologies. Prior to this, Nancy held positions of increasing responsibility at Pfizer (CovX Research, 2005-2013), X-Ceptor Therapeutics (2003-2004), MitoKor (2001-2003), and Trega Biosciences (1999-2001). Nancy’s biotechnology experience began at Genentech (1993-1996), followed by Amgen (1996-1999), where she led multiple discovery and target validation projects. Her breadth of therapeutic area expertise includes oncology, metabolic and cardiovascular diseases, dermatology, inflammation, endocrinology, and rare/ultra-rare genetic diseases. She has led programs from discovery into clinical proof-of-concept employing multiple therapeutic modalities including small molecules, antibody-drug and -peptide conjugates, peptides, proteins, and antibodies. Nancy’s development experience includes 19 IND/CTA filings, and 11 Phase 1 and 6 Phase 2 clinical proof-of-concept studies, responsible for clinical PK and biomarker study design and execution, PK modeling, clinical efficacy and safety data analysis and presentation, clinical protocol design and development, IND and Orphan Drug applications and annual reports, and complete IND-enabled submission packages for small and large molecules. She earned a Ph.D. in Endocrinology at the University of California San Francisco, followed by post-doctoral training in the Fishberg Research Center for Neurobiology at The Mount Sinai School of Medicine in New York, NY.

Assoc Prof

Dr. Lewis is an Assistant Professor of Pediatrics and Bioengineering at the University of California, San Diego. He received his BS in biochemistry at Brigham Young University, and his PhD at UC San Diego, where he focused on proteomics and developing novel approaches for analyzing biological big data using genome-scale systems biology modeling techniques. Dr. Lewis completed his postdoctoral training at the Wyss Institute at Harvard Medical School, where he worked on genome editing and the use of systems biology for the interpretation of genetic screens. Dr. Lewis' lab integrates all of his previous work by focusing heavily on the use of systems biology and genome editing techniques to map out and engineer the cell pathways controlling mammalian cell growth, protein synthesis, and protein glycosylation.

VP Biology

Dr. Yang Li is Vice President of Biology at Surrozen. He holds a Ph.D. degree in Cell Biology from Stanford University, and has over 20 years' experience in the biopharmaceutical industry with successes in advancing drug molecules from concept to clinic. Dr. Li has expertise in several classes of targets from enzymes, transcription factors, to membrane receptors and secreted hormones. He has 80 peer-reviewed publications and over 25 published patent applications.

CEO

Dr. Qingcong Lin is CEO of Biocytogen Boston Corporation, focusing on gene-targeting, humanized mouse models, RenMab/antibody discovery collaboration. Prior to joining Biocytogen, Dr. Lin was SVP of Shenogen. Prior to Sheongen, Dr. Lin led an antibody engineering group at Pfizer. Before joining Pfizer, he worked at Wyeth and Harvard Medical School as Director of Gene Modification Lab. Dr. Lin received Ph.D. from Albert-Einstein College of Medicine and completed his postdoctoral training at Harvard Medical School.

Vice President of Research

Lippy is Vice President of Research at AlivaMab Discovery Services. He has over two decades of experience in the generation and characterization of antibodies from in vivo systems.  Prior to joining AlivaMab Discovery Services, Lippy led therapeutic antibody discovery projects at Pfizer, Igenica, Ablexis and Lake Pharma. Lippy received his Ph.D. from Harvard University and did postdoctoral research at the Genomics Institute of the Novartis Research Foundation in San Diego.

Associate Director

Dr. Liu is currently an Associate Director in the CMC Dossier Development group at Sanofi. She has worked on developing analytical characterization methods to understand structure-function relationship and critical attributes of biological drug products, including mAb, bispecific antibodies, fusion proteins, recombinant lysosomal enzymes, and gene therapy products. She has strong expertise in LC/MS method development, protein structure characterization, degradation pathway, and comparability studies. Before joining Sanofi/Genzyme, Dr. Liu worked as a Senior Scientist at Wyeth, Ariad, and Abbott Laboratories. She earned her Ph.D. in Chemistry from the University of Michigan Ann Arbor.

Associate Professor

Professor Rihe Liu’s laboratory at the Eshelman School of Pharmacy and Carolina Centre for Genome Sciences at UNC Chapel Hill focuses on the directed molecular evolution of novel multifunctional target-binding molecules from natural and unnatural biopolymer libraries with high diversity and use the resulting affinity ligands in various modalities, including the protein, the mRNA as well as the engineered immune cells, to specifically target cancer cells or modulate the immunosuppressive tumor microenvironment for combination immunotherapy.

Assoc Dir & Sr Scientist II

Brian Long received his Ph.D. in Microbiology and Immunology from The University of North Carolina, Chapel Hill in 2004 and pursued post-doctoral training at The Gladstone Institutes and the University of California, San Francisco where he investigated the role of innate immunity in HIV disease pathogenesis. Following his post-doctoral training, he continued as a Research Scientist in the Division of Experimental Medicine at UCSF where he worked on the development and standardization of humanized mouse models for the evaluation of HIV immunology, therapeutics and drug discovery. Brian joined BioMarin in June of 2014 and is currently an Associate Director in Translational Sciences and Immunogenicity Assessment where he provides immunologic expertise to drug programs across developmental stages and develops immunogenicity and safety strategies for novel biologic therapeutics. Brian has over 20 years of experience in immunology and infectious disease, autoimmunity, cell signaling, cancer biology and drug development.

Exec Dir Bioanalytical Dev

Mark Ma is Executive Director of Bioanalytical Development at Alexion Pharmaceuticals. His group provides bioanalytical and Biomarker support to Alexion projects, including large molecule, small molecule, and RNAs. Before Alexion, Mark was a director of large molecule bioanalytical sciences at Amgen. Mark has been active in American Association of Pharmaceutical Scientists (AAPS) and service as chair of PK assay group within Ligand Binding Assay committee. Mark had held several academic research positions with UCLA and MMRI. His professional career outside of industry includes being a reviewer for several scientific journals and giving lectures to local colleges/universities.

Senior Director

Dr. MacLeod is currently leading the Cell Therapy Discovery Team at Precision BioSciences. His team is responsible for cell therapy discovery research and preclinical development efforts using Precision’s ARCUS gene-editing technology to engineer human T cells for cancer therapy. Dr. MacLeod was the lead author on a manuscript describing Precision’s process for engineering off-the-shelf allogeneic CAR T cells published in Molecular Therapy and is co-inventor on several granted and pending patents related to Precision’s off-the-shelf CAR T technology. Precision’s first cell therapy product, PBCAR0191, a gene-edited allogeneic CAR T cell candidate targeting CD19, developed in collaboration with Servier, is currently in clinical trials. Prior to joining Precision, Dr. MacLeod was an Investigator at GlaxoSmithKline working on immunomodulatory drug discovery programs. He performed his postdoctoral work at the International AIDS Vaccine Initiative Neutralizing Antibody Center at the Scripps Research Institute, and at the University of California, San Diego. Dr. MacLeod received a B.A. from Northwestern University with a double major in Biochemistry and Psychology, and a Ph.D. in Molecular Pathology and Biomedical Sciences from the University of California, San Diego.

Director, Business Development

Dr. Craig Magee is the Director of Business Development for the Life Science division at Daylight Solutions and is working to deliver disruptive mid-IR sensor and microscopy tools into the biomedical and pharmaceutical markets.Prior to joining Daylight, Dr. Magee worked in a variety of applications, sales and business development roles within the Life Sciences analytical and spectroscopic instrumentation sector including most recently with Protetin Simple and ThermoFisher Scientific.

Prof & Vice Chair

Don is a founder and serves as President and Chief Executive Officer (CEO) of ePD. He is primarily responsible for new business development, client relations, and oversight of all scientific and business activities at ePD. Don received a Pharm.D. and Ph.D. degree in Pharmaceutical Sciences from the State University of New York (SUNY) at Buffalo. Don has accumulated 15+ years of experience in partnering with pharmaceutical companies, the FDA, and research institutes on applications of pharmacometric and systems modeling in drug development and pharmacotherapy. Don has contributed to over 130 peer-reviewed publications and brings a unique and global perspective to developing pharmacometric and systems-based strategies in drug development and understanding sources of individual and population-level variability in drug responses. Don is a Professor of Pharmaceutical Sciences at SUNY at Buffalo and has served as a Visiting Professor at the University Paris Descartes from 2007 to 2013. He currently serves on the Pharmaceutical Sciences and Clinical Pharmacology Advisory Committee to the FDA and as an expert member of the Board of Pharmaceutical Sciences at FIP. Don also serves as an Associate or Consulting Editor at CPT:Pharmacometrics & Systems Pharmacology (CPT:PSP), and Pharmacology, Research & Perspectives (PRP). Don is a Fellow and Past-President of the International Society of Pharmacometrics (ISoP) and is a Fellow and will be President-Elect of the American College of Clinical Pharmacology (ACCP). Don is also a Fellow of the American Association of Pharmaceutical Scientists (AAPS) and the American Association for the Advancement of Science (AAAS).

Sr. Engineer I

Krishnakumar Malu's research focuses on utilizing multi-omics tools to improve development of bioprocesses in complex biologic proteins manufacturing. He has currently been working at Biogen for a little over 1.5 years developing cell culture processes. Prior to joining Biogen, he worked at Momenta Pharmaceuticals for 2 years, developing cell lines for production of novel therapeutic proteins, as well as biosimilars. Krishnakumar Malu has a Ph.D. in Biomedical Engineering and Biotechnology from University of Massachusetts, Lowell.

Asst Prof Pathology & Immunology

No bio available.

V.P. Business Development

No bio available.

Sr Scientist

Dr. Amit Kumar is a Senior Scientist in the Biologics Upstream Process Development department at Merck & Co., Inc. His past work experience includes Postdoctoral Research in Epigenetics in the department of Cell and Molecular Biology at St. Jude Children's Research Hospital. He received his Ph.D. in Chemical and Biomolecular Engineering from Johns Hopkins University at Dr. Michael Betenbaugh's lab, and B.Tech. in Chemical Engineering from Indian Institute of Technology Madras. He has been active in the area of recombinant protein production and expression for over 10 years. He has worked extensively on integrating systems biology with metabolic engineering, and has used OMICs techniques to identify and enhance the quantity and quality of recombinant protein production in mammalian cell lines.

Exec Dir & Head

Patrick Mayes, PhD, is Executive Director, Head of Biotherapeutic Research at Incyte. Dr. Mayes was previously Director of Biology and was an Early Development Leader for the Immuno-Oncology and Combinations discovery performance unit at GlaxoSmithKline. He has developed novel therapeutic antibodies which modulate innate and adaptive immune responses utilizing a variety of biotherapeutic platforms including Fc-engineered monoclonal antibodies (mAbs), bi-specific mAbs, domain antibodies (dAbs) and antibody-drug conjugates (ADCs) and has initiated and lead programs combining immune targeted therapies as well as others combining immunotherapies with tumor targeted agents.

Henry Beckman Professor

Professor Maynard received her undergraduate degree in Human Biology from Stanford University, followed by a PhD in Chemical Engineering from the University of Texas at Austin, and post-doctoral studies at Stanford University. She returned to the UT Austin as a faculty member in the Department of Chemical Engineering in 2007. Her research group aims to develop advanced antibody therapeutics to treat infectious diseases, using a combination of biological and engineering principles. Her group has developed antibodies to prevent and treat pertussis and shown that these are highly protective in adolescent and neonatal baboon models of disease. Newer work is focused on strategies to re-direct T cells to eliminate virally-infected cells.

CEO & Founder

John McCafferty was one of the founders of Cambridge Antibody Technology (CAT, now Medimmune) in 1990 and published the first paper/patent describing antibody phage display. After 12 years at CAT he returned to academia at the Sanger Institute and the University of Cambridge. In 2012 John formed IONTAS, a small innovative biotechnology company using phage display to develop novel antibody therapeutics. IONTAS have also developed a novel technology for construction of very libraries in mammalian cells by using CRISPR/Cas 9 and TALE nucleases to efficiently direct the integration of a library of antibody genes into single genomic locus within a population of cells.

Chief Scientific Officer

Dr. McNally has an extensive background in bioanalytical assay development and program leadership spanning nearly 20 years working in the pharmaceutical and biotechnology industry. Prior to joining BioAgilytix, Dr. McNally was Executive Director at CRISPR Therapeutics, where he lead a team of scientists to develop a portfolio of assays to support development of gene-based therapeutic candidates throughout their lifecycle. He has also previously held roles at Genzyme, Pfizer, EMD Serono, and Shire which have given him broad experience in the development of large molecule, gene therapy, and cell therapy biotherapeutics. Dr. McNally is a recognized thought leader in the development and application of bioanalytical methods used in regulatory submissions and is specifically skilled in progression of biotherapeutics from research through clinical development. He has a special interest in the immunogenicity of biotherapeutics and leads an industry-wide working group to address this issue. A key part of his role at BioAgilytix is advising on emerging scientific developments and providing scientific and regulatory guidance. Dr. McNally obtained his B.S. in Biology from Mississippi State University, his Ph.D. Viral Immunology from Louisiana State University School of Medicine in Shreveport, and his Post-Doc in Viral Immunology from University of Massachusetts Medical School.

Sr Principal Research Scientist

Mike obtained his PhD in Chemistry from the University of Edinburgh in Prof. Bob Baxter’s lab and then moved to Brown University in RI to pursue postdoctoral research with Prof. David Cane on engineering polyketide synthases to produce “unnatural” natural products. He was an early employee of the biotech company Phylos Inc., founded by Brian Seed and Nobel Laureate Jack Szostak to advance the utility of mRNA display in the discovery of high affinity binding proteins through in vitro selection. There he successfully applied mRNA display towards the identification of drug-binding proteins using tissue-derived libraries. Since joining Abbott Laboratories in 2004 and now AbbVie, he has helped provide key molecular/cellular pharmacology support and project leadership to both small molecule and biologics drug discovery programs within Immunology Discovery. He currently leads a group within Global Biologics Discovery that is focused on the identification of novel biologic therapeutics to treat patients with cancer, autoimmune disease or neurological disorders.

Field Application Scientist

No bio available.

Sr Scientist

Dr. Meyer's undergraduate studies were at the University of Texas in Austin, followed by graduate studies at Massachusetts Institute of Technology, and post-doctoral work at Texas A&M University. Joining a small biotech company, Xenomics, we developed isolation techniques and PCR probes for cancer diagnostics. Later at a CRO, Dr. Meyer gained experience in Good Laboratory Practice documentation, along with immuno-assay development and validation to support PK and ADA sample analyses. For the past 8 years, Dr. Meyer has been supporting anti-drug antibody detection at GSK, primarily with the Meso Scale Discovery electrochemiluminescence platform.

Ms

Julija Mezhyrova studied Biochemistry at the Goethe University Frankfurt and gained additional practical experience at the Paul Ehrlich Institute in Darmstadt and at Harvard Medical School in Boston. She is currently working on her PhD thesis at the Goethe University Frankfurt at the Institute of Biophysical Chemistry. Focus of her thesis is the characterization of bacteriolytic phage proteins, being promising targets for future antibiotic development and for industrial applications in the vaccination of livestock.

CEO

Dr. François-Thomas Michaud co-founded and became CEO of Feldan in 2007 while completing his PhD degree in chemical engineering at Laval University. Through the years, Dr. Michaud and his team worked on a research project that led to the inception of a cell-penetrating proprietary technology, the Feldan Shuttle. This technology, which gives access to a wide range of intracellular therapeutic targets, has the potential to bring a whole new class of therapies to the clinic. Over the years, Dr. Michaud’s value-creating vision shaped the business model of the company, at the center of which resides the Feldan Shuttle. Through his leadership, exceptional human qualities and determination, Dr. Michaud has successfully built in Québec City a sustainable organization that today stands alongside biopharmaceutical global leaders. In addition to position itself as one of the top Canadian SMI-biotech leaders, Dr. Michaud is actively engaged in the business, academic and entrepreneurial communities of the Province of Québec as an administrator, speaker and mentor.

Prof

Jeffrey S. Miller, MD, received a Bachelor of Science degree from Northwestern University in Evanston, Illinois and received his MD from Northwestern University School of Medicine. He completed an internship and residency in Internal Medicine at the University of Iowa in Iowa City. After completing a post-doctoral fellowship in Hematology, Oncology and Transplantation at the University of Minnesota, he joined the faculty in 1991. Dr. Miller is currently a Professor of Medicine at the University of Minnesota, Division of Hematology, Oncology and Transplantation. He is the Deputy Director of the University of Minnesota Masonic Comprehensive Cancer Center. He has more than 20 years of experience studying the biology of NK cells and other immune effector cells and their use in clinical immunotherapy with over 200 peer-reviewed publications. He is a member of numerous societies such as the American Society of Hematology, the American Association of Immunologists, a member of the American Society of Clinical Investigation since 1999. He serves on the editorial board for Blood and is a reviewer for a number of journals and NIH grants. Dr. Miller was the recipient of the National Cancer Institute Outstanding Investigator Award for 2015.

Novartis Institutes for BioMedical Research Inc

Head Ophthalmology Therapeutics

Mark is currently the Global Head of the Pharmacokinetic Sciences Ophthalmology Therapeutic Area and Department Lead for Gene Therapies at Novartis, where he is an internal expert in Immunogenicity Risk Assessment and Gene Therapies. He has over 25 years of experience (Searle, Millennium, Novartis) in the nonclinical and clinical PK/PD of NCEs, biologics, and gene therapies. He has published over 30 peer-reviewed publications and book chapters, and presented extensively on the development of both NCEs and biologics. His current interests include the PK/PD and immunogenicity of biotherapeutics, the contribution of PK (biodistribution) and IG to the development of gene and cell-based therapies, ocular immunology, the selection of the clinical starting dose based upon the MABEL calculation, and alternative designs for FIH Clinical Trials of mAbs in healthy volunteers.

Sr Scientist

I am a senior scientist at the Cell Culture department in Genentech. I have been in this role since 2010. My research involves improving/innovating processes that result in generation of cell lines expressing bio-therapeutics (proteins and antibodies used as drugs) that grow better and yield higher titers with better product quality attributes. Bachelor: University of California Berkeley, Molecular and Cell Biology. PhD: Harvard University, in Biological and Biomedical Sciences. Post-doctoral fellow at Massachusetts Institute of Technology (MIT). Post-doctoral fellow at Genentech.

Graduate Student

No bio available.

Product Marketing Manager

Prem Swaroop Mohanty is a Life Sciences Product Specialist and Product Marketing Manager at Benchling. He holds an MBA from UC Berkeley, a MS from U of Illinois, Chicago, and a B.Pharm from U of Mumbai. He has over 13 years of industry experience across biopharma R&D, strategy consulting, and software product marketing. Prior to Benchling, Prem was a Sr. Consultant at Navigant, a Scientist at Allergan, and Research Scientist at deCODE.

Product Marketing Manager

Prem Swaroop Mohanty is a Life Sciences Product Specialist and Product Marketing Manager at Benchling. He holds an MBA from UC Berkeley, a MS from U of Illinois, Chicago, and a B.Pharm from U of Mumbai. He has over 13 years of industry experience across biopharma R&D, strategy consulting, and software product marketing. Prior to Benchling, Prem was a Sr. Consultant at Navigant, a Scientist at Allergan, and Research Scientist at deCODE.

Albert Einstein College of Medicine

Graduate Student

Nicholas Morano did his undergraduate education studying Biochemistry at Binghamton University. He then went on to do his PhD. in the laboratory of Dr. Steven Almo, at Albert Einstein College of Medicine, where he studies the structure and function of interactions between the immunoglobin and TNFR superfamilies.

Albert Einstein College of Medicine

Graduate Student

No bio available.

Solid Biosciences

CSO

Prior to joining Solid, Dr. Morris was a Senior Director for Pfizer’s Rare Disease Research Unit, leading their efforts in neurologic diseases and the muscle biology programs. While at Pfizer, Dr. Morris directed several small molecule and biotherapeutic development programs, including a program that led to a Phase 2 study in Duchenne Muscular Dystrophy, while also heading an internal research group responsible for advancing programs from target identification to the clinic for many of the rare neurologic and muscle-related diseases. Dr. Morris identified key external opportunities and worked closely with patient groups, academic laboratories, and other industry partners to advance drug development in the rare neuromuscular space. His scientific and drug development experience at Pfizer also included investigations into broader muscle wasting conditions, as well as tendon and bone repair biology. Prior to joining Pfizer in 2007, Dr. Morris was an Assistant Professor at Boston University School of Medicine and a founding faculty member of the Muscle and Aging Research Unit, established to investigate strategies for improving muscle function during aging or disease. He completed his Postdoctoral fellowship in the Department of Physiology at the University of Pennsylvania where he worked on multiple projects ranging from molecular aspects of muscle protein interactions through to therapeutic approaches for modulating muscle size and function. As a trained muscle physiologist, his academic pursuits have ranged from biophysical aspects of muscle contraction and enzyme kinetics to therapeutic interventions in a variety of in vivo muscle atrophy and disease models. Dr. Morris holds a B.A. in Biology from Franklin Pierce College (Rindge, NH) and a PhD in Physiology from UCLA.

Grp Leader

Dafne Müller received her doctoral degree from the University of Stuttgart in Germany. At the present she holds a group leader/lecturer position at the department of Biomedical Engineering at the Institute of Cell Biology and Immunology of the University of Stuttgart. Working in the field of recombinant antibodies for over 15 years, her current research focuses on the development of recombinant antibody-fusion proteins with immune stimulatory or costimulatory properties for targeted cancer immunotherapy.

Head

Dr. Alexander Muik is an immunologist by training heading the research group Immunomodulators at BioNTech RNA Pharmaceuticals GmbH, Mainz, Germany. He received his PhD degree in immunoloy/virology for his work on novel virotherapy approaches to treat brain cancer and has co-authored many publications in peer-reviewed journals investigating the preclinical development of oncolytic viruses. Since 2016, he is part of BioNTech, focusing his research on the clinical translation of mRNA- and antibody-based innovative immunotherapeutic concepts with special attention to immune agonist antibodies and cytokines.

Chief Engineer

Idris Mustafa is an Automation Architect, Scientist & Software Engineer currently residing in Silicon Valley, CA. He has spent the last 10+ years bridging the gap between drug discovery, clinical diagnostics, and technology using advanced control machines, building custom algorithms, and serving the scientific community. He has also dedicated much of his career to creating software interfaces that increase efficiency in the lab and change the face of the way robots, databases, and people interact. His research is at the cutting-edge of liquid-handling robotics innovation; leveraging 3D-printing technologies and machine learning concepts to drive productivity. Finally, he believes his "Faith in God and passion to optimize the human condition" will continue to fuel breakthroughs in the world of science and technology. Autonomi, an Idris Dot Solutions service, was founded in 2020 and built to fill in the prevalent automation gaps seen in the Biotechnology/Pharmaceutical industries. One of the bottlenecks in drug discovery/development and sample analysis is the laborious, error-prone and time-consuming nature of manual pipetting/experimentation. Automating workflows mitigates human error, saves time, reduces ergonomic stress, increases sample throughput and improves data quality/reproducibility. Leveraging Autonomi, we combine our insights and skills to push the envelope on laboratory automation. Our ultimate goal is to improve efficiency in the lab so that researchers can focus on delivering essential medicines and results to patients.

Assistant Professor

Dr. Nasr received his Ph.D. in Pharmaceutical Sciences from Northeastern University, and did post-doc fellowship training at Harvard Medical School. Currently, he's a group leader at Brigham and Women’s Hospital in the Renal and Engineering in Medicine divisions within the Department of Medicine.

Executive Director

Dr. Nastri is currently the Executive Director of Antibody Discovery at Incyte Corp. His group is responsible for end-to-end discovery and engineering of monoclonal and bispecific antibodies for oncology applications. His group uses both immunization, as well as display approaches for the generation of lead molecules, which are further optimized by a combination of in vitro and in silico approaches. Dr. Nastri started his career in the antibody field at Dyax Corp., where he developed and co-invented key technologies utilized to build the Dyax Fab libraries. He then headed the Antibody Technologies group at EMD Serono, where he implemented new approaches for selecting antibodies by single cell B-cloning and phage display. He became an Inventor of Avelumab, a clinical-approved anti PD-L1 antibody. He joined Pfizer CTI as a Biotherapeutic Site Head in NY, where he collaborated with local academic leaders to enable and advance novel therapeutic programs. During his career, Dr. Nastri became an inventor of multiple antibody therapeutic molecules and antibody discovery enable technologies, while participating in a number of projects resulting in IND applications.

Head, Rare Diseases Drug Discovery Unit

Madhu is currently the Head of the Rare Diseases Drug Discovery Unit in Research at Takeda, and his group’s mandate spans ideation through to development of molecules to take into the clinic. Madhu has been working on discovery programs in rare diseases for almost a decade at Shire. In previous roles Madhu was Pfizer, and as faculty at the University of Texas Southwestern Medical Center in Dallas. Madhu holds a Baccalaureate in Electronics and Telecommunications Engineering from the University of Madras, India, and a doctorate in Neurobiology from Northwestern University, Illinois.

Peter MacCallum Cancer Ctr

Grp Leader & Assoc Prof

Paul Neeson completed a PhD at the University of Melbourne (Pathology), before doing a post-doc in the Paterson lab (University of Pennsylvania) where he worked on B-cell lymphoma vaccines. He returned to Melbourne and established the human immunology translational lab (HITRL) in Cancer Immunology Research at the Peter MacCallum Cancer Centre. The Lab’s focus is on chimeric antigen receptor (CAR) T cells for solid tumors and human immuno-oncology. His lab has adopted ‘state of the art’ technologies to explore the immune context of human cancer. This information is being used to better understand immune escape, to stratify patients for immunotherapy combination treatments (including CART cells) for better outcomes in patients with solid tumors

Application Scientist

With over 10 years of experience in the membrane proteins field, Dr. Rony Nehmé has a deep and solid understanding of GPCRs biology, pharmacology and structural studies. He was an Investigator Scientist in the lab of Prof. Chris Tate (MRC-LMB in Cambridge) prior to joining Creoptix in 2018 as an Application Scientist. He holds a PhD in molecular biology from the Université de Nice-Sophia Antipolis in France.

Full Prof

Dario Neri was born in Rome on 1 May 1963, but grew up in Siena (Italy). He studied Chemistry at the Scuola Normale Superiore of Pisa and earned a PhD in Chemistry at the Swiss Federal Institute of Technology (ETH Zürich), under the supervision of Professor Kurt Wüthrich (Nobel Prize Chemistry 2002). After a post-doctoral research internship (1992-1996) at the Medical Research Council Centre in Cambridge (UK), under the supervision of Sir Gregory Winter (Nobel Prize Chemistry 2018), he became professor at ETH Zürich in 1996. Dario Neri is currently Full Professor of Biomacromolecules at the Department of Chemistry and Applied Biosciences, ETH Zürich. The research of the Neri group focuses on the engineering of therapeutic antibodies for the therapy of cancer and other angiogenesis-related disorders and on the development of DNA-encoded chemical libraries. Dario Neri is a co-founder of Philogen (www.philogen.com ), a Swiss-Italian biotech company which has brought various antibody products into multicenter clinical trials for the treatment of cancer and of chronic inflammatory conditions. Dario Neri has published 400 articles in peer-reviewed scientific journals. He is the recipient of the ISOBM Abbott Prize 2000, of the Amgen-Dompe’ Biotec Award 2000, of the Mangia d’Oro 2001, of the Prous Award 2006 of the European Federation of Medicinal Chemistry, of the Robert-Wenner-Prize 2007 of the Swiss Cancer League, of the SWISS BRIDGE Award 2008, of the Prix Mentzer of the French Medicinal Chemistry Society in 2011, of the Phoenix Prize 2014 and of an ERC Advanced Grant in 2015.

CEO, Director

Anton is a biomedical professional, scientist, innovator, entrepreneur and venture capitalist with more than 15 years of industry and academic experience in research and drug development. At ImmunoBiochem Corporation, Anton is leading the development of a new class of tumor microenvironment-targeted anti-cancer therapeutics. Anton was formerly the Director of Drug Development at Armour Therapeutics Inc., a biopharmaceutical company developing a new class of anti-cancer therapeutics for prostate, breast and ovarian cancers. Throughout his career, Anton worked on R&D and consulting projects with several biopharmaceutical companies developing biological therapeutics and immunotherapies in oncology. Anton has expertise in cancer research, immunology, chemistry, regenerative medicine and gene therapy, and authored more than 25 peer-reviewed publications and patents. Anton obtained his PhD, MSc, and Hon. BSc degrees in medical biophysics, immunology, and biological chemistry at the University of Toronto, where he also completed postdoctoral work and his MBA at the Rotman School of Management. Anton was also a trainee of the CIHR Training Program in Regenerative Medicine (TPRM), Toronto General Hospital, University Health Network. Anton was a founding board member, and former CCO and organizing committee member of the Canadian Science Policy Centre (Toronto, ON) – a national organization promoting science policy in Canada. Anton has led several venture capital investments in biomedical and healthcare companies at GreenSky Capital.

Assoc Prof

Ho Leung Ng completed his BA at Harvard University, PhD at UCLA, and postdoctoral fellowship at UC Berkeley in the areas of structural biology and crystallography. After leaving UC Berkeley, Dr. Ng worked with Brian Kobilka at ConfometRx on GPCR crystallography. Dr. Ng then moved to the University of Hawaii as an Assistant Professor and later to Kansas State University as Associate Professor. His current research focuses on experimental and computational structure-based drug design for GPCRs, nuclear receptors, and kinases. Dr. Ng is also interested in applications of machine learning for chemistry and drug design.

Prof

Dr. Nielsen holds a shared position as Professor of Immunoinformatics and Machine Learning at the Department of Health Technology, Technical University of Denmark, and the Universidad Nacional de San Martin, Argentina. He graduated with a Masters in Physics from the University of Copenhagen, and obtained his Ph.D. (also in Physics) from the McGill University, Canada. The core of Dr. Nielsen’s research deals with the development of novel and advanced data-driven prediction methods for pattern recognition in biological systems. He is a pioneer in the field of immunoinformatics and a key inventor of several state-of-the-art methods for T and B cell epitope discovery currently used worldwide. He has published more than 200 articles, books, and book chapters within the fields of immunology, immunoinformatics, computational biology, data mining, and machine learning.

Mustang Bio Inc

Chief Technology Officer

Dr. Knut Niss, Ph.D. has been Chief Technology Officer at Mustang Bio, Inc. since March 2018. He joined Mustang in March 2017 as Vice President of Operations, where he initiated and oversees the establishment of Mustang’s cell therapy manufacturing facility. Prior to Mustang, Dr. Niss was Cell Therapy Asset Leader at Biogen, where he oversaw CMC-related activities for gene-edited hematopoietic stem cell and lentiviral gene therapy programs for sickle cell disease and hemophilia, respectively. Earlier in his career, Dr. Niss was Senior Technical Project Leader at Novartis’ cell therapy manufacturing facility in Morris Plains, New Jersey, where he directed the transfer and implementation of the CTL019 process from Penn to Novartis. He also served as Senior R&D Program Manager at EMD Millipore, where he established processes for the large-scale expansion of adult and pluripotent stem cells. Dr. Niss began his career in senior research positions in Pfizer’s Regenerative Medicine and Immunology groups. He holds a Ph.D. in molecular biology from Humboldt University of Berlin, and an M.S. in microbiology from the University of Göttingen in Germany. Dr. Niss completed his postdoctoral research at Boston Children’s Hospital and the Dana-Farber Cancer Institute.

Head

D. Olive has been a pioneer and leader in the co-signalling field since 1990. His work is dedicated to tumor immunology with a major emphasis on innate immunity and co-signalling molecules. Selected major breakthroughs: 1) Identification of signaling pathways involved in CD28 and ICOS costimulatory molecules; 2) Demonstration that BTN3A1/CD277 is a major inducer of Vg9Vd2 response; 3) identification of the function of BTLA and HVEM in the regulation of immune function; 4) Identification of molecular mechanisms associated to NK cells impairment in AML patients; 5) first identification of alteration of NK cells in the tumor bed in breast and prostate cancer; 6) First in man clinical trial using anti-KIR mAbs in AML patients; 7) Deciphering of of ICOS ICOSL interaction in the regulation of Tregs in lymphomas.

Assistant Professor

Dr. Owen is an Assistant Professor in the Pharmaceutical Chemistry department at the University of Utah. He is also an Adjunct Assistant Professor in the Internal Medicine, Bioengineering, and Medicinal Chemistry Departments. His lab utilizes protein engineering and bioconjugation techniques in developing therapeutic and diagnostic platforms to enable precision medicine.

Sr Scientist

Rahul Palchaudhuri (Senior Scientist at Magenta Therapeutics, Cambridge MA) is the Program Lead for MGTA-117, Magenta’s most advanced ADC program for conditioning prior to hematopoietic stem cell transplantation (HSCT). Prior to joining Magenta Therapeutics, Dr. Palchaudhuri conducted his postdoctoral studies at Harvard University, where he demonstrated the feasibility of ADC-based approaches to enable HSCT in murine models. Rahul Palchaudhuri holds a Doctorate in Chemistry from the University of Illinois at Urbana-Champaign, and an undergraduate degree in Chemistry from Grinnell College.

Scientist I

Christina has been a core member of the Antibody Discovery team within Biologics Drug Discovery for over 10 years. She graduated from MIT with a BA in Chemical Engineering and a MA in Bioengineering from the University of Pennsylvania. She has extensive experience working with phage and yeast display systems, including the Dyax and Adimab platforms. She has led numerous Antibody Discovery campaigns for a variety of targets, including therapeutic candidates for oncology, autoimmune disease, fibrosis, MS, and neurological indications.

Executive Vice President & Head

Prof. Paul Parren, is an expert in antibody research, translational science and drug development. He is Exec. VP and Head of R&D at the start-up company Lava Therapeutics. He is also a biotech consultant and a professor of molecular immunology at the Leiden University Medical Center. Previously, he was head of preclinical development and research at Genmab and he was an Associate Professor at The Scripps Research Institute in La Jolla, CA. He invented and developed the approved therapeutic antibodies ofatumumab (Arzerra) and daratumumab (DARZALEX) and clinically validated antibody platform technologies for generating bispecific and enhanced-function antibodies. He received his PhD from the University of Amsterdam (1992).

Sr Research Scientist

Since joining AstraZeneca in 2017, Saleha has worked on and produced high quality protein reagents for a number of early discovery projects. Her specific focus within the team is in the area of protein QC and sample preparation for specialist downstream applications. More recently, she has been developing and prosecuting biochemical assay strategies for screening and hit dicovery. Prior to joining AstraZeneca, Saleha studied Biochemistry at the University of York, followed by an MSc in Bioscience Technology with a short time also spent at CRUK at the London Research Institute. She completed her PhD and first Postdoc at the University of Leicester in partnership with UCB Pharma. Her work looked into characterising the structures and function of antagonists of the Wnt signalling pathway using NMR, EM and several other biophysical techniques.

President

Dr. Paul, a Ruth L. Kirschstein Fellow, obtained his Ph.D. in Structural Biology and Biophysics from Purdue University under Cynthia Staffaucher. After his Ph.D., he joined a mass spectrometric-focused lab at NIEHS for his post-doctoral studies. After his post-doctoral studies, he created the Biophysical Analysis Lab at the Bindley Bioscience Center, where he introduced a comprehensive and successful biophysics analytical program that included AUC, CD, ITC, DLS, DSC, SPR, BLI, and MALLS techniques. He was also the Director of the Purdue Proteomic Facility, where he implemented new analytical methods for looking at large proteomic data, PTMs, and de novo sequencing and quantitation (MRM/SRM, LFQ and isotopic labeling). He then went into the industrial sector, where he led programs that focused on discovery, process development, cGMP method development and validation, cGMP manufacturing, and quality control for a variety of systems: small molecules; proteins; mAbs; ADCs; and gene therapy. He started his own CRO/consulting company, BioAnalysis, LLC, where he focuses on high-level biophysical and analytical chemistry collaborations. His deep expertise includes: >25 peer reviewed publications; business acumen; CMC strategy; BLA/MAA submissions; QA/QC; and analytical method development/validation. He has proven to be an invaluable resource to his clients.

Director

I received my PhD from University of Michigan Ann Arbor in protein crystallography. I then did a postdoc at The Scripps Research Institute where I studied broadly neutralizing HIV-1 antibodies, solved crystal structures of such antibodies bound to viral envelope glycoproteins and peptide antigens. After taking a scientist position at Adimab LLC, my focus on antibody engineering blossomed into a bispecific antibody discovery and optimization and cell selection approaches for membrane protein targets. Currently, as Director of Antibody Engineering, my work on bispecifics and membrane protein targets continues alongside platform optimization, antibody format research and development, and developability.

Sr Scientist

Dr. Kate Peng received her Ph.D. from the University of California Berkeley. Following her post-doctoral training at Berkeley, Dr. Peng worked in the biotechnology industry with a focus on developing cell-based methods for high-throughput screening of drug candidates targeting GPCRs. Dr. Peng joined Genentech in 2007 and is currently an Associate Director/Senior Scientist in the Department of BioAnalytical Sciences. Her focus is on development of bioanalytical strategies and methods to enable assessment of the pharmacokinetics, pharmacodynamics, immunogenicity of protein therapeutics from early development to clinical, as well as post-marketing stages. Dr. Peng has led bioanalytical efforts for supporting the development of protein therapeutics that target cancer immunotherapy, immunology, neurology, and cardiovascular disease areas.

Senior Vice President

Li Peng is Senior Vice President of Research and Early Product Development at Palleon Pharmaceuticals, a leading biotechnology company focused on developing Glyco-Immune Checkpoint therapeutics to treat cancer. Li led the invention of two core platform technologies at Palleon – the EAGLE platform for targeting glyco-immune checkpoint ligands and the HYDRA platform for enabling patient stratification. Previously, she worked at Medimmune/AstraZeneca for ~10 years with increasing responsibilities from antibody engineering and characterization to leading drug discovery programs and cross-functional project teams. Li has a PhD in Biochemistry, MS in Genetics, and BS in Biology. She has published ~30 papers and authored >10 patents and applications.

Lead Microbiology Associate

Michele Perry received her Bachelor of Science degree in Biology and Biotechnology from Worcester Polytechnic Institute. She has 11 years of experience in the science field, including quality control, DMPK, manufacturing, and research and development at companies such as Seres Therapeutics and T2 Biosystems. Most recently, Michele has been developing release assays for live bacterial products in the Analytical Development group at Synlogic, Inc. She has also had an integral role in the opening of the new Quality Control Laboratory at Synlogic.

Sr Scientist

No bio available.

Assoc Dir ICD

Kelli began her career in biologics in 2006, as a principal investigator in the Immunochemistry Research and Development department at PPD. In her current role as an Associate Director of R&D, she provides oversight to method development and validation of quantitative (PK), immunogenicity (ADA), and biomarker methods. During her tenure at PPD, her focus has been on the development of robust, drug-tolerant immunogenicity assays, validation of biosimilar methods, and the life-cycle management of extended-use methods.

Vice President

Dr. Plyte is Vice President of Immune Oncology at Merus N.V. in Holland where he is responsible for building a world class pipeline of bispecific antibodies to treat multiple cancers. Using the Merus Biclonics® platform his team are developing bispecific antibodies to many immunological targets for the modulation of the immune system. Prior to Merus, Dr. Plyte was Senior Director of Immune Oncology at Molecular Partners, Switzerland, where his team were using DARPins to modulate immunological targets. At Boehringer Ingelheim, Germany, Dr. Plyte was Director in Cancer Immunology and Immune Modulation where various of his teams worked on the development of biologics to treat cancer, ocular diseases, diabetes and neurodegenerative diseases including the development of a blood brain barrier shuttle. He has over 20 years of experience in the Pharma industry.

Head

Laurent Poirot is an immunologist with over 16 years of experience in biotech. In graduate school, he studied immunology in the laboratory of Diane Mathis and Christophe Benoist (Université de Strasbourg, France and Harvard Medical School, Boston, MA). His Ph.D. thesis focused on the pathogenic mechanisms of autoimmune diabetes. In 2004, he joined the Genomics Institute of the Novartis Research Foundation (GNF, San Diego, CA) as a postdoctoral fellow, where he performed high-throughput genetic/genomic studies in immune cells (cDNA/siRNA screens, mouse mutagenesis, and microarray databases). In 2009, he joined Cellectis (Paris, France) where he first studied gene therapy approaches in hematopoietic stem cells and developed gene editing tools for CAR T-cells. In 2013, he became Head of Early Discovery and in 2018, VP of the Immunology division. His team develops innovative tools to improve immunotherapies based on gene-edited CAR T cells. He splits his activities between Paris and New York.

Head

Dr. Alison Porter first joined Lonza in 1998 where she spent 13 years working in the Cell Culture Process Development Group. In 2011, she joined Fujifilm Diosynth Biotechnologies as Head of the Mammalian Cell Culture R&D Department and led the development of the company’s mammalian expression platform. Alison re-joined Lonza in 2016 as Head of Process Development Sciences. She now serves as the Head of Expression System Sciences where she provides in-depth scientific and technical leadership to those working with Lonza’s GS Gene Expression System®.  Alison specialises in expression systems and the construction of recombinant cell lines. She has a Ph.D. in Biotechnology from the University of Manchester.

Vice President

Dr. Jonah Rainey is the Vice President of Antibody Therapeutics at Gritstone Oncology. He holds a PhD in Biochemistry from Tufts University and completed postdoctoral training at the University of Wisconsin and the Salk Institute. He has been actively engaged in discovery, research, and development of bispecific antibodies in a biotech setting for 12 years. He is an inventor on several patents and applications describing novel bispecific platforms as well as current clinical candidates that exploit these platforms. Dr. Rainey led or had major contributions to research and early development of at least three current clinical candidates in phase 1 and 2, and led many additional advanced preclinical programs in oncology, infectious disease, autoimmunity, and other therapeutic areas. Previously, he was the CEO of OrioleBio, a consulting and research organization focused on discovery through early development of biologics. Industry experience spans small biotech (MacroGenics, MabVax) and large pharma settings (MedImmune/Astrazeneca).

Senior Scientist

Sarav Rajan obtained his PhD from McGill University and a post-doctoral fellowship from the University of Toronto, specializing in the use of phage display to isolate therapeutic antibodies. He has been at AstraZeneca in the department of Antibody Discovery and Protein Engineering for over 7 years where he has earned several distinctions, including company-wide innovation awards. He currently manages a team in Maryland that has pioneered a novel discovery platform that captures and screens the natively-paired antibody repertoire from millions of B cells.

Endowed Prof

Ted Randolph received his Ph.D. in Chemical Engineering at the University of California, Berkeley. He worked as a post-doctoral fellow at the Ecole Polytechnique Federale de Lausanne, and then joined the Department of Chemical Engineering at Yale University as an Assistant Professor. After promotion to Associate Professor, he was named to Yale’s first John J. Lee Junior Professorship Chair in Chemical Engineering. In 1993, Dr. Randolph accepted the Patton Associate Professorship Chair in the Department of Chemical Engineering at the University of Colorado. He currently serves as the Gillespie Professor of Bioengineering, co-Director of the University of Colorado’s Center for Pharmaceutical Biotechnology. Dr. Randolph is a National Science Foundation Presidential Young Investigator, and received the AIChE Professional Progress Award and has twice received the American Pharmacists’ Association Ebert Prize. He is an author of more than 230 peer-reviewed journal articles in the areas of biopharmaceutical formulation, lyophilization of proteins, protein-solvent interactions in non-aqueous environments, and protein refolding. Dr. Randolph is an inventor on 27 US patents, and has cofounded three companies, RxKinetix Inc., Barofold, Inc. and VitriVax Inc.

Dir

Dr. Redmond received his undergraduate degree in Biology at the University of California, Davis prior to pursuing a PhD in Immunology at The Scripps Research Institute in La Jolla, CA. His doctoral studies focused on understanding how defects in the regulation of “killer” CD8 T cells can lead to the onset of autoimmune (type 1) diabetes. After obtaining his PhD, Dr. Redmond joined Dr. Andrew Weinberg’s laboratory at the Earle A. Chiles Research Institute (EACRI) at Providence Cancer Institute in Portland, OR. Dr. Redmond’s post-doctoral research focused on tumor immunotherapy, which harnesses the power of the patient’s own immune system to seek out and destroy tumors. Specifically, he investigated the mechanisms by which an agonist anti-OX40 mAb enhanced CD8 T cell function to eradicate tumors. Currently, Dr. Redmond is an Associate Member and Director, Immune Monitoring Laboratory at the EACRI and an Adjunct Assistant Professor in the Department of Molecular Microbiology and Immunology at Oregon Health & Science University. His work seeks to elucidate the mechanisms by which combinatorial approaches to cancer immunotherapy, such as the provision of T cell co-stimulation plus checkpoint blockade augment the development of potent effector CD8 T cells capable of eliminating tumors.

Executive Director

Dr. Janice Reichert is an internationally recognized expert in the development of antibody therapeutics. She is Executive Director of The Antibody Society, a non-profit association representing individuals and organizations that engage in antibody-related research or development. Dr. Reichert is also Founder and Editor-in-Chief of mAbs, a peer-reviewed, PubMed-indexed biomedical journal that focuses on topics relevant to antibody research and development, and Managing Director of Reichert Biotechnology Consulting LLC, a pharmaceutical business intelligence research firm. Dr. Reichert writes frequently on development trends for antibody therapeutics, including the annual ‘Antibodies to watch’ articles published in mAbs, and she has presented her research results as an invited speaker at conferences held worldwide.

Principal Scientist

No bio available.

Fusion Pharmaceuticals Inc

Director of Preclinical Development

John Rhoden, Ph.D., is Director of Preclinical Development at Fusion Pharmaceuticals, a biotechnology company developing therapeutic alpha-emitting radiopharmaceuticals for the treatment of solid tumors. Prior to Fusion, Dr. Rhoden was a Principal Research Scientist in the Department of Drug Disposition at Eli Lilly and Company. He received his B.S. in Chemical Engineering from N.C. State University and a Ph.D. in Chemical Engineering from M.I.T. under the guidance of Prof. K. Dane Wittrup. During his career in industry, Dr. Rhoden has worked in ADME, PK/PD, and translational sciences on discovery and early development teams in a variety of therapeutic areas, including oncology, immunooncology, autoimmunity, and kidney disease. Dr. Rhoden’s professional interests lie in using simple mathematical models to understand complex systems, interrogate hypotheses, and guide experiment design and interpretation.

Dir Product Quality

Over the last 16 years, Ken Riker has led Quality teams to develop and execute filing strategies for three successful global filings for biologics. Most recently he led the effort to evaluate the risk associated with the integrated control strategy for Celgene’s first cell therapy product. He lives in the Seattle area.

Yale University School of Medicine

Associate Professor

Dr. Jesse Rinehart is an Associate Professor with tenure in the Department of Cellular & Molecular Physiology at the Yale University School of Medicine with a joint appointment in the Systems Biology Institute. Dr. Rinehart’s research aims to understand and “decode” the roles of protein phosphorylation in humans. His laboratory uses an innovative combination of quantitative phosphoproteomics and synthetic biology study protein phosphorylation in single proteins and protein networks. Recently, research in Dr. Rinehart’s laboratory has been accelerated by their Escherichia coli based technologies that enable site-specific incorporation of phosphoryation into human proteins. Dr. Rinehart received his PhD in Molecular Biophysics and Biochemistry from Yale in 2005. He studied protein synthesis and the evolution of the genetic code during his graduate work. His did his postdoctoral research with Richard Lifton in the Department of Genetics at Yale and focused on protein phosphorylation in physiological systems.

Yale School of Medicine

Assistant Professor

Aaron Ring received his undergraduate training at Yale University and entered the Stanford Medical Scientist Training Program for his MD and PhD degrees. At Stanford, he worked in the laboratories of K. Christopher Garcia and Irving Weissman to use structure-based protein engineering to develop new cytokine and immune checkpoint therapies for cancer. He additionally developed novel methodologies in protein engineering to create biologic agents against challenging targets such as G protein coupled receptors (GPCRs). Aaron joined the faculty of the Yale Department of Immunobiology in 2016 as the Robert T. McCluskey Yale Scholar. The focus of his research is to understand and manipulate the activity of immune receptors using structural and combinatorial biology approaches.

Principal Research Scientist I

Wendy Ritacco is a Principal Research Scientist at Abbvie and specializes in design and optimization of conditionally activated biologics. She is dedicated to the creation of efficacious treatments without deleterious side effects. She received her M.S. from Worcester Polytechnic Institute and has more than 25 years of biopharmaceutical industry experience.

Asst Prof

Gabriel Rocklin did his Ph.D. research at the University of California, San Francisco, supervised by Brian Shoichet and Ken Dill. As a postdoctoral fellow with David Baker at the University of Washington, he pioneered the use of large-scale protein design to understand protein biophysics. In 2019 he started his independent lab in the Department of Pharmacology and Center for Synthetic Biology at Northwestern University. There, his group develops high-throughput methods to understand protein biophysics and to design new protein therapeutics.

Grp Leader

Carlos R. Reis has been working in the Protein Engineering field for over 15 years. During this time, he has worked with several small and large biotech companies at different stages of product development, from discovery to manufacturing. His primary focus has been on protein therapeutics, antibody structure-function relationships, protein and antibody design and developability assessment of biologics during early discovery. He is currently a group leader in Antibody Engineering at GSK located in Stevenage, UK, working at the interface between discovery and development on new protein engineering strategies and technologies to optimize the developability profile of candidate molecules and accelerate their development. Carlos R. Reis received his PhD in Mathematics and Natural Sciences from the University of Groningen, NL, and completed his postdoctoral training in computational biology and cell engineering at UT Southwestern Medical Center in Dallas, USA. His main contributions include the development of novel computational protein design methods to generate potent and selective anti-cancer therapeutics targeting TNFR members, the discovery of new regulatory links between therapeutics and endocytic trafficking and the design of novel effector-based protein engineering strategies to restore self-tolerance in autoimmunity. He is passionate about science, mentorship and applying innovative protein design principles to engineer effective therapies that can potentially save lives.

John and Ann Doerr Medical Director

Eben L. Rosenthal is a surgeon-scientist who serves as the John and Ann Doerr Medical Director of the Stanford Cancer Center. He is a Professor of Otolaryngology and Radiology (courtesy) and is clinically active as an oncologic and microvascular reconstructive surgeon. Dr. Rosenthal conducts early-phase clinical trials for diagnostic and therapeutic agents for the treatment of solid tumors. He is part of a multidisciplinary team of clinicians and basic scientists that perform preclinical studies, nonhuman primate IND-enabling studies, and first-in-human clinical trials. The lab also focuses on molecular imaging of fluorescently labeled therapeutic antibodies to measure cellular delivery of therapies to tumors and adjacent tissues. Ongoing clinical trials include brain, lung, pancreas, skin, and head and neck tumors.

Asst Prof & Scientific Dir Lymphoma Program

Marco Ruella, M.D., is Assistant Professor of Medicine in the Division of Hematology/Oncology and the Center for Cellular Immunotherapies and Scientific Director of the Lymphoma Program at the Hospital of the University of Pennsylvania. His research focuses on the study of the mechanisms of relapse after chimeric antigen receptor T cell (CAR T) immunotherapies with the goal of rationally designing combined, innovative immunotherapies for relapsing/refractory leukemia and lymphoma. He is the author of numerous peer-reviewed publications on targeted immunotherapies for hematological cancers and is an inventor in several patents on CAR T therapy. His work has been recognized through numerous awards, including the inaugural SITC EMD-Serono Cancer Immunotherapy Clinical Fellowship (2014), the AACR-BMS Oncology Fellowship in Clinical Cancer Research (2015), the ASH Scholar Award (2016), a NIH K99-R00 award (2017), the “Paola Campese” Award Leukemia Research (2017), the Cancer Support Community Award (2018), and most recently, the 2018 American Society of Hematology Joanne Levy, MD, Memorial Award for Outstanding Achievement. Dr. Ruella obtained his medical degree with high honors and completed his specialization in clinical hematology at the University of Torino, Italy. After completing his fellowship, he was an attending physician in the Hematology and Cell Therapy Division of the Mauriziano Hospital and an Instructor at the Biotechnology School at the University of Torino. From 2012, he was a postdoctoral fellow, and then an instructor at the University of Pennsylvania in the Center for Cellular Immunotherapies, where he worked with Drs. June and Gill until appointment to his current position in 2018.

Chief Scientific Officer

Dr. Sandig is recognized for seminal fundamental and applied research in cell and vector biotechnology, and the development of innovative vaccine technologies. Notably, for instigating and developing the cell-line development program at ProBioGen AG, which resulted in one of the leading CHO platforms, the co-development of the CHO-Freedom Kit with LTC (now Thermo-Fisher), and the development of glycoengineering technologies, and notably GlymaxX at ProBioGen.

Principal Scientist

Wendy is a principal scientist at Genentech. She leads the Translational Mass Spectrometry group within the research organization. Her group focuses on mass spectrometry-based strategies to help elucidate protein structure and function. She has a particular interest in native mass spectrometry and it's evolving role in the biopharmaceutical industry. During her more than twenty years at Genentech Wendy has co-authored 70 papers and edited two books, and is happy that she continue to learn new things every day.

Biomedical Engineer

Sumona Sarkar is a Biomedical Engineer at the National Institute of Standards and Technology in Gaithersburg MD. She has been at NIST for 8 years with a focus on cell material interactions for tissue engineering and regenerative medicine, and analytical methods for cell and gene therapy. She serves as a subject matter expert and project leader in ISO TC 276: Biotechnology with particular expertise in cell count, viability, and characterization. Prior to joining NIST Sumona received her Ph.D in biomedical engineering from Drexel University, and her M.S. from Boston University.

CSO

Aaron is CSO of the Biopharma Vertical at Twist Bioscience.  Prior to Twist, he served as Chief Scientific Officer of LakePharma, leading the California Antibody Center, which discovers novel antibody therapeutics for its clients. He also oversaw all discovery research functions both as Vice President of Protein Sciences at Surrozen, and previously, as Vice President of Research at Sutro Biopharma, Inc. He also held director level positions at both Oncomed and Dyax Corp.

 

Prof & Dir

Philipp Scherer is Professor and Director of the Touchstone Diabetes Center at the University of Texas Southwestern Medical Center in Dallas. He received his Ph.D. degree from the University of Basel, Switzerland, followed by post-doctoral training the Whitehead Institute at MIT in Cambridge. In 1997, he joined the faculty of the Albert Einstein College of Medicine where he was a Professor for Cell Biology and Medicine. Throughout his career, he has maintained an interest in processes related to cellular and systemic energy homeostasis. He identified adiponectin, one of the first secretory factors to be described that almost exclusively originate in adipose tissue and which is currently widely studied by many different research groups. Current efforts in his laboratory are focused on the identification and physiological characterization of novel proteins that serve as potential links between the adipocyte, liver, the pancreatic beta cell and the processes of whole body energy homeostasis, inflammation, cancer and cardiovascular disease. Scherer has been on the faculty of UT Southwestern Medical Center since 2007 as a member of the Department of Internal Medicine. He holds the Touchstone Distinguished Chair in Diabetes Research and is a member of the Simmons Comprehensive Cancer Center. He was awarded the 2015 Banting Medal for Scientific Achievement from the American Diabetes Association, the 2017 European Association for the Study of Diabetes (EASD) / Novo Nordisk Foundation Diabetes Prize for Excellence and the 2018 Manpei Suzuki Prize in Japan.

Principle R&D Scientist

Stephanie earned her Ph.D. in Biochemistry from Washington University in St. Louis, where she used neuronal cell models to discover and interrogate novel signaling pathways that regulate neurite structure.  As a Senior Scientist, she used precision genome engineering technologies, such as CRISPR/Cas9, to create cellular models for use in drug and cell therapy research and development.  Stephanie is currently a Principal Scientist at MilliporeSigma and leads a team of Cell Design Studio scientists.

COO & Head

Dr. Stefan R. Schmidt MBA, currently serves as Head of Operations/COO at BioAtrium AG, a joint venture of Lonza and Sanofi in Visp, Switzerland. Previously he held the position as CSO and other senior executive roles at Rentschler Biopharma with overall responsibilities for development and production for more than 5 years. Before that, he was CSO at ERA Biotech in Barcelona, directing the company’s R&D efforts. Prior to that, he worked for 7 years at AstraZeneca in Sweden where he led the unit of Protein Sciences as Associate Director. He started his leadership career at Biotech companies in Munich where he built up protein biochemistry teams for Connex and GPC-Biotech.

Owner & Consultant

Timothy Schofield is Owner & Consultant at CMC Sciences, LLC. Prior to joining this Tim worked at a Senior Advisor in Global Vaccines Technical R&D at GlaxoSmithKline, at MedImmune as Senior Fellow in Analytical Biotechnology, Arlenda, Inc. as Managing Director and Head of Nonclinical Statistics, at GSK in US Regulatory Affairs, and at the Merck Research Laboratories heading the Nonclinical Statistics unit, supporting research, development and manufacture of Merck pharmaceuticals, biologics and vaccines. Tim received a Bachelor of Science degree in Mathematics from Lafayette College, and a Master of Arts degree in Statistics and Operations Research in 1976 from the Wharton School of the University of Pennsylvania. Tim is a member of the USP Statistics Expert Committee and has participated in industry initiatives related to Quality by Design, analytical method development and validation, stability and specifications. He is the Chairman of the IABS Publications Committee where he is responsible for business and strategy related to the journal Biologicals.

CEO

Taylor co-founded Shattuck Labs and currently serves as Chief Scientific Officer and a member of the Board of Directors. Taylor is the lead inventor of Shattuck’s ARC technology platform. Prior to Shattuck, Taylor served as Chief Scientific Officer of Heat Biologics, Inc. where he was a co-inventor of significant elements of Heat's ImPACT and ComPACT technology platforms. He was also the co-inventor of TNFRSF25 agonist technology developed by Pelican Therapeutics, where he served as Chairman of the Scientific Advisory Board.

Sr Principal Scientist

Stefan is senior principal scientist and project leader in pRED (Roche Pharma Research and Early Development). He has been active in antibody and cell line development since 1997. In this function he discovered several therapeutic antibodies through all phases from the beginning until entry into human. This included standard antibodies and novel complex format antibodies. In previous positions at Boehringer Mannheim GmbH he worked in oncology projects, developed non-viral and viral vectors for gene therapy programs and tools for molecular biology. Dr. Seeber received his Ph.D. in Biology from the Eberhard Karls University in Tuebingen, Germany. Recently he setup a gene therapy program to develop CMC for AAV-production at Roche, following exactly the session strategy “Transitioning from Therapeutic Proteins to Cell and Gene Therapies”.

Assoc Prof

Prof. Dhaval K. Shah is an Associate Professor of Pharmaceutical Sciences at the State University of New York at Buffalo. Prior to becoming faculty, Prof. Shah served as a Principal Scientist in the Translational Research-Modeling & Simulation group at Pfizer Inc. His research focuses on understanding the determinants for the absorption, distribution, metabolism, and elimination (ADME) of protein therapeutics. His lab uses the principles of Pharmacokinetics-Pharmacodynamics (PK-PD) Modeling & Simulation to support the discovery, clinical translation, and late-phase development of novel biologics like engineered antibodies, multi-specific proteins, immuno-oncology agents, engineered T cells, and antibody-drug conjugates. He has developed several pioneering system PK/PD models for ADCs, and continues to develop mechanism models to understand and improve pharmacological behavior of ADCs.

University of California, San Francisco

Associate Professor

Nina is currently an Associate Professor in the Division of Hematology-Oncology at University of California, San Francisco. Her research focuses on multiple myeloma clinical trials, specifically immunotherapy and cellular therapy. She performed the first-in-human clinical trial of umbilical cord blood-derived natural killer cell therapy for myeloma and am currently one of the three lead principal investigators for the multi-center BMT CTN 1401 dendritic cell vaccine trial for myeloma patients. Additionally, she is the institutional PI for numerous cellular therapy and immunotherapy protocols.

Prof

Susan Sharfstein is a Professor of Nanobioscience at SUNY Polytechnic Institute in Albany, New York. Professor Sharfstein received her B.S. in chemical engineering with honors from Caltech in 1987 and her Ph.D. in chemical engineering from UC Berkeley in 1993. Her interests include mammalian and microbial cell bioprocessing, control of protein glycosylation, metabolic engineering, biosensing, and development of systems for high-throughput screening of nucleic acids and small molecules. She is the author of over 65 papers and book chapters in the fields of biotechnology and bioprocessing.

Prof

Dr. Shusta received his Ph.D. in 1999 from the University of Illinois where he studied the production and engineering of antibodies and T-cell receptors using yeast. He followed this with postdoctoral training at the University of California-Los Angeles where he helped pioneer molecular level analyses of the blood-brain barrier. Currently, Dr. Shusta is the Howard Curler Distinguished Professor in the Department of Chemical and Biological Engineering at the University of Wisconsin. His research focuses on the development of molecular and cellular engineering tools that can help gain a better understanding of blood-brain barrier transport and function. He has been recognized by an NSF Career award, the American Chemical Society BIOT division young investigator award, among others, and was recently elected fellow in the American Institute for Medical and Biological Engineering.

Grp Leader Protein Expressions

Did my graduate work at the University of Manitoba in Canada followed by Post-Doctoral Fellowship at the University of Michigan. Worked at Cayman Chemical for 7 years as the Manager for the Protein Core Group. I then moved to Massachusetts to join Beryllium Discovery just after their acquisition by UCB but before the integration. Currently I am the Protein Expression Lead at UCB Boston. The team expresses proteins in prokaryotic (primarily E. coli) and eukaryotic (insect and mammalian) expression systems.

Director, Business Development-JAX Services

Basile is a trained viral immunologist with a Ph.D. from the TU Munich, Germany. After a brief antibody engineering related stint at Roche Diagnostics, he pursued a post-doctoral fellowship at LUMC in Chicago, followed by a five year infectious diseases junior faculty tenure at RUMC also in Chicago. Over the last 6 years, Basile held various field positions as Field Application Scientist, Market Development Scientist and in Business Development.

 

Medical Officer, Div of Clinical Evaluation & Pharmacology

No bio available.

Senior Director

Dimitris Skokos is a Director in the Immunity and Inflammation department at Regeneron Pharmaceuticals as well as an adjunct faculty Professor at Rockefeller University. He was born and raised in Athens, Greece. In 1998, he double majored receiving degrees in BioMedical Science and Biotechnology, from Ecole Superior in Paris and in Cellular Biology and Physiology from the University of Paris, with High Honors. After earning his Master’s and PhD in Molecular Immunology from Pasteur Institute, he joined the laboratories of Ralph Steinman (Nobel laureate, 2011) and Michel Nussenzweig at Rockefeller University, studying the role of tolerance and immunity in inflammation. In 2008, he joined Regeneron Pharmaceuticals, Inc., where he and his team are leading Regeneron’s efforts in cancer immunotherapy. Dimitris holds more than 10 patents and 25 publications and was part of the team that developed the recently FDA approved treatment for metastatic cutaneous squamous cell carcinoma, Libtayo. He has had the honor to work with esteem scientists, George D. Yancopoulos and Roy P. Vagelos.

Peter MacCallum Cancer Centre

Senior Research Officer

Clare is a Senior Research Fellow at the Peter MacCallum Cancer Centre, Australia. Her current research interests are in understanding the interaction between the immune system and cancer, and in the use of immunotherapy to treat cancer. These interests include the use of genetically modified T cells (CAR T cells) to treat solid cancers. Clare has published over 30 papers in high-impact journals including first and last authorships in Nature Medicine, PNAS, Cancer Research, Clinical Cancer Research and Cancer Discovery. She has obtained over $3M research funding, including 3 fellowships and 6 project grants. Her accomplishments have been acknowledged with a number of awards including the Seymour and Vivian Milstein Young Investigator Award for notable contributions to basic and clinical research in Switzerland (2012), a Joseph Sambrook Award in Research Excellence (2014), and the respected Mavis Robertson Award (2018) that is given each year to a female principal investigator considered to exhibit the greatest promise as a leader in breast cancer research in Australia.

Regeneron Pharmaceuticals, Inc.

Senior Director

Dr. Eric Smith received his PhD in Microbiology and Immunology from Duke University in 1997. Following a postdoctoral fellowship at NYU he joined Regeneron in 2002 as a member of the Antibody and Trap Technologies group, where he worked on cytokine traps and related molecules. In 2008 he was a founding member of the Bispecific Antibodies team and is currently the Sr. Director of Bispecifics at Regeneron.

Head

Noel completed his PhD and subsequent post-doctoral studies at the University of Cambridge in the field of metabolic disease. Noel joined Lonza in 2009 and was involved in the setup of the human primary cell-based assay platform and now Heads the Immunology group which develops assays to screen products for immunogenicity and immunotoxicity risk. The Lonza Cambridge site is focused on the development and provision of services to support the development of new biotherapeutic proteins and vaccines with a particular focus on immunogenicity, immunotoxicity, manufacturability and protein expression.

Senior Vice President, Research & CSO

No bio available.

Head

Peggy Sotiropoulou joined Celyad in 2017. As Director of the R&D department, she leads a broad-ranging internal research program that aims to develop new strategies in CAR T cell design to target haematological and solid malignancies. Prior to Celyad, Peggy spent 17 years in Academic research in oncology and immunooncology. Before moving to industry, Peggy was associate Professor in the Université Libre de Bruxelles, in Brussels, Belgium, leading research in fundamental oncology and published landmark papers in top tier scientific journals. The aim of Peggy in Celyad is to translate cutting-edge research and innovation into actual treatments for patients.

CSO

After his PhD in Cell and Molecular Biology from Texas A&M, Colby joined MassBiologics. There, he led programs to discover and advance mAbs for the prevention, treatment or diagnosis of infectious and endogenous diseases. He later joined the Kanyos Bio Protein Engineering team to develop therapeutics based on a novel antigen-specific immune tolerance platform. Colby joined Abveris Antibody as Chief Scientific Officer to usher in new antibody discovery tools and build a premium discovery engine. 

Principal Investigator

Dr. Carole A.C. Sourbier is a Principal Investigator with the Office of Biotechnology Products, Center for Drug Evaluation and Research, FDA. She received her Ph.D. from the Louis Pasteur University, Strasbourg, France, and then joined the National Cancer Institute, NIH, where she led multiple translational research projects related to aberrant metabolic processes. At FDA, in addition to her regulatory duties, Dr. Sourbier is leading a research group that investigates how to evaluate and compare the quality of products, with a focus on metabolism and metabolic bioassays.

Assistant Professor

Dr. Jamie Spangler earned a Bachelor of Science degree in Biomedical Engineering at Johns Hopkins University and went on to complete a PhD in Biological Engineering at MIT under the supervision of Professor K. Dane Wittrup. She conducted postdoctoral training in Professor K. Christopher Garcia’s lab at Stanford University School of Medicine, and then launched her independent research group at Johns Hopkins University in July 2017, jointly between the departments of Biomedical Engineering and Chemical & Biomolecular Engineering. Dr. Spangler’s lab, located in the Translational Tissue Engineering Center at the School of Medicine, applies structural and mechanistic insights to re-engineer existing proteins and design new proteins that therapeutically modulate the immune response. In particular, her group is interested in engineering immune molecules such as antibodies, cytokines, and growth factors for targeted treatment of diseases such as cancer, infectious diseases, and autoimmune disorders. Dr. Spangler’s work has been recognized with honors including a National Defense Science and Engineering Graduate Fellowship, a Leukemia & Lymphoma Society Career Development Fellowship, a V Foundation Scholar award, and a Maryland Stem Cell Research Fund Discovery award.

CEO

Philipp Spycher obtained his Master’s Degree and Ph.D. from ETH Zurich (Switzerland) at the interface of Material Science and Protein Engineering. During his post-doctoral work at the Paul Scherrer Institute (PSI, Switzerland), he introduced the novel approach using transglutaminases for antibody conjugation that led to the discovery of the Araris Linker Technology. Philipp won the PSI Founder Fellowship as well as several other prices and grants to commercialize the technology. He is now leading Araris as CEO and managed to assemble a world-class team of co-founders and co-workers.

Business Development Manager

Anthony is leading BD at Rapid Novor where he has merged his training in biomedical engineering with his passion for research. He's focused on helping pharma and biotech companies leverage REpAb to sequence mAbs from polyclonal sera in patients or animal models, as well as immune system profiling using NovorIg

Univ of Natural Resources & Life Sciences

Assoc Prof

Associate Professor at the Department of Biotechnology (BOKU), head of the working group microbial fermentation and principal investigator in the Austrian Center of Industrial Biotechnology (ACIB). The working group has established an integrated systems approach for bioprocess development and is focused on the implementation of PAT and QbD concepts in bioprocessing and rational host cell design. CHO, E. coli, insect cells and vero cell lines are used as expression systems for production of a representative set of biopharmaceuticals (mABs, Fabs, scFvs, VLPs, viruses, DNA.

Doctor

Lars Stöckl joined Glycotope in 2005 and besides other tasks was responsible for the establishment of the GlycoExpress plattform and for setting up the glyco-analytical lab. Since January 2020 he heads the service department of Glycotope.

Before the appointment at Glycotope he gained experience in cell line engineering and protein chemistry during his PhD and Postdoc at the Robert Koch-Institute /Berlin, the Charite / Berlin and the Breakthrough Breast Cancer Research / London.

Principal Scientist

Julie received her bachelor’s degree in chemistry with concentration in biochemistry from Duke University. She did her graduate work with Anna Marie Pyle at Columbia University, focusing on the folding of large catalytic RNAs. She then moved to Boston and carried out postdoctoral work in Susan Lindquist’s lab at Whitehead Institute, using yeast as a model for characterizing the disruption of cellular pathways caused by misfolding of alpha synuclein. She joined Bristol Myers Squibb in 2009 and works in discovery, utilizing in vitro selection methods to identify biologic leads for therapeutic targets.

Field Application Scientist Manager

Sean is working as as Manager of Field Application Scientist. He has over sixteen years of research, scientific writing and collaborative experience with the life scientists. He has worked as Field Application Scientist in Bio-Rad for several years. He holds a Ph.D of Biology and a Masters of Business Administration from McGill University, Montreal. He completed his undergraduate studies in Biochemistry at the Institute for Cooperative Education, Concordia University, Montreal.

 

Albert M Mattocks Prof

Peter Tessier is the Albert M. Mattocks (Endowed) Professor in the Departments of Chemical Engineering, Pharmaceutical Sciences and Biomedical Engineering, and a member of the Biointerfaces Institute at the University of Michigan in Ann Arbor, MI. He received his Ph.D. in Chemical Engineering from the University of Delaware (2003, NASA Graduate Fellow) and performed his postdoctoral studies at the Whitehead Institute for Biomedical Research at MIT (2003-2007, American Cancer Society Fellow). Tessier started his independent career as an assistant professor in the Department of Chemical & Biological Engineering at Rensselaer Polytechnic Institute in 2007, and he was an endowed full professor at Rensselaer prior to moving to the University of Michigan in 2017. Tessier’s research focuses on designing, optimizing, characterizing and formulating a class of large therapeutic proteins (antibodies) that hold great potential for detecting and treating human disorders ranging from cancer to Alzheimer’s disease. He has received a number of awards and fellowships in recognition of his pioneering work: Pew Scholar Award in Biomedical Sciences (2010-2014), Humboldt Fellowship for Experienced Researchers (2014-2015), Young Scientist Award from the World Economic Forum (2014), Young Investigator Award from the American Chemical Society (2015) and NSF CAREER Award (2010-2015).

Specialist, Orbital Bioreactors

No bio available.

Sr Scientist

Christy Thomson received her PhD in Biochemistry from McMaster University where her research focused on protein structure and function. Her post-doctoral research at the University of British Columbia examined the human antibody response to common pathogens such as HCMV and H1N1. Since joining Amgen in 2012, her focus has been biologic discovery. Dr. Thomson is leader of the Antibody Characterization and Discovery Team which brings together diverse expertise and strategies aimed at early identification of B cells specific to target and the development of assays and reagents to differentiate lead antibodies meeting design goals.

Asst Prof

Greg M. Thurber is an Assistant Professor of Chemical Engineering and Biomedical Engineering at the University of Michigan. His work focuses on applying fundamental biotransport principles to design novel therapeutics and molecular imaging agents. Prof. Thurber received his training in protein therapeutics at MIT under the guidance of Dr. Dane Wittrup. He then completed his in vivo training in molecular imaging in the laboratory of Dr. Ralph Weissleder at Mass General Hospital and Harvard Medical School. Since joining the faculty at Michigan, he has delivered 26 invited talks at major pharmaceutical companies, national and international conferences, and university departmental seminars. Prof. Thurber works with several pharmaceutical companies as a consultant, collaborator, and/or member of their scientific advisory board. He and his students have presented their interdisciplinary work at chemistry, chemical engineering, and pharmaceutical science conferences. Prof. Thurber has authored 39 peer-reviewed journal publications, 3 book chapters, and numerous conference proceedings. He has received several awards including an NIH K01 award and the National Science Foundation CAREER award.

CEO & Founder

Dr. Tolcher is CEO and Founder of NEXT OncologyTM, San Antonio, Texas, a newly founded Phase I group that seeks to transform early clinical trials. NEXT Oncology’s mission is to accelerate the next breakthrough medicines for cancer and the vision is to be the most successful and respected Phase I program in oncology research. Dr. Tolcher served as President and Co-Founder of START LLC from 2009- 2018, one of the world’s largest Clinical Phase I and early drug development operations in cancer medicine with 5 locations in San Antonio Texas; Grand Rapids, Michigan; Madrid Spain; and Shanghai China. Dr. Tolcher is a medical oncologist who has over 25 years’ experience in early drug development and clinical trials. He has been involved in many of the initial phase I studies of new agents that subsequently were FDA approved for the treatment of cancer including pembrolizumab (Keytruda), copanlisib (Aliqopa), trastuzumab emtansine (Kadcyla), regorafenib (Stivarga), liposomal vincristine (Marqibo), cabazitaxel (Jevtana), carfilzomib (Kyprolis), gefitinib (Iressa), erlotinib (Tarceva), and eribulin (Halaven). He is currently the principal investigator on 20 phase I clinical studies, is a reviewer for the Journal of Clinical Oncology, Clinical Cancer Research, and Annals of Oncology. He has chaired the Developmental Therapeutics Review Committee for the American Association of Clinical Oncology Annual Scientific Program. He has a member of over 20 Scientific Advisory Boards for both large and small pharmaceutical companies, as well as a member of the Board of Director for 2 biotechnology companies. Dr. Tolcher has over 100 peer-reviewed publications in scientific journals including Nature, Proceedings of the National Academy of Sciences (USA), Journal of Clinical Oncology, and Clinical Cancer Research, as well as an author of nine book chapters.

Managing Director

Michael brings an extensive knowledge and expertise in molecular genetics, signal transduction, and cell engineering and is the inventor of the iLite™ reporter gene technology. Michael is the author of more than 200 articles on cytokines, biotechnology, and immunogenicity. 

CMO

Elizabeth (Beth) G. Tréhu, M.D., FACP, is Chief Medical Officer of Jounce Therapeutics, a clinical-stage immuno-oncology company dedicated to transforming the treatment of cancer by matching the right immunotherapy to the right patient. Dr. Tréhu designed and conducted her first cancer immunotherapy clinical trials in the early 1990s as an Assistant Professor and Translational Researcher at Tufts University School of Medicine, where her research focused on reducing the toxicity of high-dose interleukin-2. She has held oncology leadership positions in drug development from IND through post-marketing at Millennium Pharmaceuticals, Genzyme Corporation, Infinity Pharmaceuticals and Promedior, Inc., and joined Jounce in 2015 to build and lead the clinical organization.

CTO

Dr. Trinklein is the Chief Technology Officer at Teneobio. Teneobio employs a sequence-based approach for antibody discovery that leverages next-generation sequencing and high-throughput functionally assays to develop fully-human multi-specific antibodies. Prior to Teneobio, Dr. Trinklein was a co-founder of SwitchGear Genomics, a venture-backed company that was acquired in 2013. Dr. Trinklein served as the Technical Director of the Stanford ENCODE project and received his Ph.D. from Stanford University. Dr. Trinklein has published over 20 peer-reviewed papers and is an inventor on over 15 patents.

Co-Founder & CTO

Dr. Alem Truneh is a senior pharmaceutical executive with over 30 years of experience in biomedical R&D, executive management, and business development. His expertise includes small-molecule and biologics drug discovery and development in a broad range of therapeutic areas, including cancer, autoimmunity, and infectious diseases. He spent 17 years at GlaxoSmithKline, where he helped advance several products, including biologics and small-molecule drugs, from early drug discovery through advanced clinical trials, post-market product differentiation, and line extensions. Dr. Truneh has served in senior executive positions at several biotechs and start-ups, including Agenus, TolerRx, NKT Therapeutics, and ImCheck Therapeutics, as SVP of R&D, CSO, CTO, CEO, and as a member of Boards of Directors, and is a co-founder of NKT Therapeutics and ImCheck Therapeutics. Dr. Truneh has co-authored over 100 scientific papers and reviews in distinguished and first-rung journals, and is a co-inventor in over 35 patents.

Assistant Professor

No bio available.

Sr Scientist

I got my Bachelor’s in Chemistry and Philosophy at Creighton University in Omaha working in synthetic organic chemistry. I then went to the University of Minnesota, where I received my Ph.D. working under Will Pomerantz developing protein-observed fluorine NMR as a ligand discovery technique. Since then I’ve been working in the high-throughput protein engineering group at AbbVie Bioresearch Center to design, produce, and analyze proteins in high-throughput.

Graduate Student Researcher

A 5th year Ph.D. candidate in Brandon Ruotolo’s group at the University of Michigan. His work has primarily focused on the characterization of native biotherapeutic antibody structures, and the development of stability assays and high throughput screening using ion mobility-mass spectrometry.

University of Minnesota Masonic Cancer Center

Lion Scholar and Professor; Director, Section on Molecular Cancer Therapeutics; Professor

Professor of Radiation Oncology and member of the NCI-designated Mesonic Cancer Center, University of Minnesota Director of the Laboratory of Molecular Cancer Therapeutics. Currently, Lion Scholar. PhD from Ohio State University in Immunology and Oncology 1978. Past Leukemia Society and ACS scholar. Over 200 career publications on PubMed. Specialist in the genetic engineering of new anti-cancer drugs designed to use antibodies to selectively target carcinoma and leukemia. Have assembled a drug facility at the U of M that allows cGMP production of biological drugs. Have FDA sponsored 3 drugs and taken these from Bedside to the clinic.

Sr. Director & Head of Protein Engineering

Tom Van Blarcom received his Ph.D. in Chemical Engineering from The University of Texas at Austin, where he worked on the development and application of cell surface display systems for antibody engineering. Afterwards he joined the Protein Engineering Department at Pfizer’s South San Francisco location where he continued to develop novel technologies for antibody engineering including cell surface display, synthetic antibody library design and library synthesis technologies and applied them to improve the development of therapeutic monoclonal antibodies, bispecific antibodies and CAR T cells. Since then, he has continued his work on CAR T cells by joining Allogene Therapeutics, a clinical-stage biotechnology company pioneering the development of allogeneic CAR T cell (AlloCAR TTM) therapies for cancer. At Allogene, Tom oversees all protein engineering activities and contributes to various aspects of CAR T cell design and engineering.

Research Grp Leader

In 1990, after his PhD at the Free University in Amsterdam, Dr. Joop van den Heuvel started as Post-Doc at the German Research Centre for Biotechnology (GBF) in Braunschweig, Germany, first as part of the research group gene expression, later as part of the department of biochemical engineering. Since 2002, the institute was renamed to Helmholtz Centre for Infection Research. At that time, Dr. van den Heuvel changed to the department of Structural Biology. In 2007, he became group Leader of the recombinant protein expression (RPEX) in the department of structure and function of proteins (SFPR) and established the Helmholtz Protein Sample Production Facility (PSPF) in Braunschweig. Dr. van den Heuvel successfully participated as work package leader in the EU Project "ComplexInc", is member of the ESFRI programm "Instruct" infrastructures for structural biology and is currently active in the EU-Project Intruct-Ultra. The main expertise of Dr. van den Heuvel is in the production of ultra-pure proteins in E. coli, Pichia pastoris, BEVS, TGE and stable mammalian cell line engineering of proteins required for bacterial and viral infection research. In 2020, the focus dramatically changed to protein molecules relevant for CoV-2 research.

PostDoc Lab for Systems & Synthetic Immunology

Dr. Rodrigo Vazquez-Lombardi is a research scientist specializing in therapeutic protein engineering and immunology. As part of his PHRT Postdoctoral Fellowship at ETH Zurich (D-BSSE, Basel), he is currently developing novel tools for use in T cell immunotherapy applications.

Novo Nordisk Research Ctr

Dir Protein Engineering

Erik has a background in Biotechnology from the Royal Institute of Technology in Stockholm, Sweden, from where he earned his PhD working on alternative scaffold affinity proteins. This was followed by postdoctoral training on high-throughput protein production and characterisation at the Novo Nordisk Foundation Center for Protein Research in Copenhagen, Denmark. After joining Novo Nordisk A/S in Denmark in 2011, Erik has held various project and line manager positions in protein science, bioinformatics and laboratory informatics. Since 2017 Erik is head of Discovery Biologics at Novo Nordisk Research Center Seattle, WA, responsible for compound generation, analysis and characterization in the discovery pipeline.

Key Account and Technology Officer

Dr. Birgit Viira is a Key Account and Technology Officer at Icosagen.

Principal Scientific Liaison

Mr. Walfish is Principal Science & Standards Liaison at United States Pharmacopeia (USP) responsible for the Statistics Expert Committee. Prior to this role Mr. Walfish was Principal Statistician at Becton Dickinson in Franklin Lakes, NJ responsible for supporting continuous improvement efforts and process development for worldwide operations. Mr. Walfish has held roles at GE Healthcare, Human Genome Sciences and Chiron. Steven was President of Statistical Outsourcing Services, a consulting company that provides statistical analysis and training to the FDA regulated industries. Mr. Walfish brings over 30 years of industrial expertise in the development and application of statistical methods for solving complex business issues. Steven has experience applying statistical methods to analytical method verification and validation and stability analysis. Mr. Walfish holds a Bachelors of Arts in Statistics from the University of Buffalo, Masters of Science in Statistics from Rutgers University and an Executive MBA from Boston University.

Centre for Cancer Immunology University of Southampton

Director

Sally Ward completed her PhD research in the Department of Biochemistry at Cambridge University in 1985 under the mentorship of Professor David Ellar. From 1988 to 1990, she carried out research on antibody repertoire technology in Sir Greg Winter’s laboratory at the MRC Laboratory of Molecular Biology in Cambridge. In 1990 she joined the University of Texas Southwestern Medical Center, Dallas, as an Assistant Professor. From 2002-2014, she was a Professor in the Department of Immunology at the same institution and in 2004 was appointed to the Paul and Betty Meek-FINA Professorship in Molecular Immunology. Since 2014, she has been a Professor at Texas A&M University Health Science Center, and has recently been appointed as Director of Translational Immunology and Professor of Molecular Immunology at the Centre for Cancer Immunology in Southampton, U.K. In 2010, she was a founding co-organizer of the Gordon Research Conference ‘Antibody Biology and Engineering’. She is currently vice president of the Antibody Society. Her interdisciplinary research involves the use of a combination of fluorescence imaging, protein engineering and in vivo studies to develop antibody-based therapeutics to treat cancer and autoimmunity.

Prof & Dir

Dr. Louis Weiner is director of Georgetown Lombardi Comprehensive Cancer Center, one of 49 National Cancer Institute (NCI)-designated comprehensive cancer centers in the United States. He holds the Francis L. and Charlotte G. Gragnani Chair and is professor of oncology and chair of the Department of Oncology at Georgetown University Medical Center. He also serves as the Director of the MedStar Georgetown Cancer Institute, a cancer service line serving patients in the Washington DC and Baltimore metropolitan areas. He is responsible for the operation and development of the cancer center, including its research, clinical, and educational missions. The clinical mission includes leading the MedStar-Georgetown Cancer Network in the metropolitan Washington area. Weiner is known for his laboratory and clinical research focusing on new therapeutic approaches that mobilize the patient’s immune system to fight cancer using monoclonal antibodies and other modalities of therapy. His current research focuses on identifying and therapeutically exploiting mechanisms employed by malignant cells to combat immune destruction. Prior to joining Georgetown Lombardi as director in 2008, Weiner served as chairman of the medical oncology department and vice president for translational research at Fox Chase Cancer Center in Philadelphia, PA, and also served as professor in the department of medicine at Temple University School of Medicine. He is an active member of the American Society of Clinical Oncology and the American Association for Cancer Research (AACR), and founded the AACR Cancer Immunology Working Group. He has served as chair of the NCI Board of Scientific Counselors for Clinical Sciences and Epidemiology and as a member of the NCI Clinical Trials Advisory Committee (CTAC). He also served on the NCI’s blue ribbon panel working group on immunotherapy for the National Cancer Moonshot Initiative and the Advisory Panel of the National Institutes of Health (NIH) Center for Scientific Research (CSR), which administers NIH research grants. He is recipient of the 2019 AACR Distinguished Public Service Award. Weiner earned his bachelor degree in biology with honors from the University of Pennsylvania and his M.D. from Mount Sinai School of Medicine. After completing his internship, residency, and service as chief medical resident at the University of Vermont’s Medical Center Hospital, he held clinical and research fellowships in hematology and oncology at Tufts University School of Medicine in Boston.

Univ of California, Irvine

Professor

Gregory Weiss is a Professor of Chemical Biology and Faculty Innovation Fellow at the University of California, Irvine (UCI) in the Departments of Chemistry, Molecular Biology and Biochemistry, and Pharmaceutical Sciences. He earned a B.S. from UC Berkeley and a Ph.D. from Harvard.

University of California, San Francisco

Professor

Wells’ group pioneered the engineering of proteins, antibodies, and small molecules that target catalytic, allosteric, and protein-protein interaction sites; and technologies including protein phage display, alanine-scanning, engineered proteases for improved hydrolysis, bioconjugations, N-terminomics, disulfide “tethering” (a novel site-directed fragment based approach for drug discovery), and more recently an industrialized recombinant antibody production pipeline for the proteome. These lead to important new insights into protease mechanisms, growth factor signaling, hot-spots in protein-protein interfaces, role of caspases in biology, and more recently determining how cell surfaces change in health and disease. His team was integral to several protein products including Somavert for acromegaly, Avastin for cancer, Lifitegrast for dry eye disease, and engineered proteases sold by Pfizer, Genentech, Shire and Genencor, respectively. He is an elected member of the US National Academy of Science, American Association of Arts and Science, and the National Academy of Inventors.

Head

No bio available.

EVP, Development

Dr. Nancy Whiting joined Seattle Genetics in March 2007, and was promoted to Executive Vice President, Late Stage Development in March 2020. She previously served as Senior Vice President, Development and Medical Affairs and Elliott Bay Site Head; Vice President, Medical Affairs; Executive Director, Medical Affairs; and Senior Medical Director, Experimental Medicine. In her current position, she has responsibility for the Clinical Development organization that is focused on late-stage clinical programs. Prior to transitioning to the pharmaceutical industry, Dr. Whiting practiced as a Clinical Oncology Pharmacist at the Seattle Cancer Care Alliance. Dr. Whiting completed her undergraduate training at the University of British Columbia and received her PharmD from the University of Washington. She also completed a residency in clinical pharmacy practice at Vancouver General Hospital. Dr. Whiting is a member of the American Society of Clinical Oncology, the American Society of Hematology, and the European Society of Medical Oncology. She serves on the Board of the Life Science Washington trade association.

Associate Director

Megan Wiberg’s career spans more than 20 years of using ligand binding assays (LBAs) to detect drug concentrations, anti-drug antibodies (ADAs), and biomarkers. Working for the CRO industry in regulated bioanalysis throughout that time has given her exposure to a wide variety of biologics and approaches across a diverse set of sponsor companies. It has also allowed her to observe the evolution of regulatory requirements for LBAs and ADAs in real time. After several years of performing assays in the laboratory, Megan served many more as a Principal Investigator for assay development, validation, and sample analysis projects. This expanded into various levels of supervisory roles, where she had the opportunity to spread her knowledge and experience to others. In her current role as Associate Director in the Immunochemistry department at PPD, she oversees a team of more than 60 scientists in support of assay validation and long-term implementation of methods for nonclinical and clinical study support.

Asst Prof

Dr. Wine graduated from Tel Aviv University in the Department of Molecular Microbiology and Biotechnology at the Faculty of Life Sciences under the supervision of Prof. Amihay Freeman and Prof Felix Frolow, where using structural biology, protein chemistry, computerized modeling and molecular biology tools, he studied various aspects of protein-protein interactions for the design of novel composite materials within the nano-biotechnology field. During his postdoctoral training at the laboratory of Prof. George Georgiou (UT, Austin), Dr. Wine focused on developing a novel approach for the in-depth analysis of the humoral response following vaccine or disease. Following his postdoc training he established his research group at Tel Aviv University. As a group leader, Dr. Wine utilizes his recently developed approach combined with earlier acquired tools to study: i) maternal-infant immunity by profiling the molecular composition, dynamics and attributes of maternal, trans-placental and breastmilk vaccine-specific antibodies; ii) Anti-drug antibodies following treatment with Biologics and ; iii) anti-bacterial antibodies to be used as next generation antibiotics. Collectively, Dr. Wine’s research group aims to address basic immunological questions as well as application-focused research for vaccine evaluation, development and design, immunodiagnostic discovery, and monoclonal antibody engineering.

CP Dubbs Professor

Prof. Dane Wittrup attended the University of New Mexico as an undergraduate, graduating Summa Cum Laude with a Bachelor's in Chemical Engineering in June 1984. Wittrup went on to attend the California Institute of Technology in Pasadena, where he worked with Prof. James Bailey on flow cytometry and segregated modeling of recombinant populations of Saccharomyces cerevisiae. After obtaining his PhD in Chemical Engineering with a minor in Biology in 1988, he spent a brief time working at Amgen before becoming an Assistant Professor of Chemical Engineering at the University of Illinois at Urbana-Champaign in 1989. He moved to the Massachusetts Institute of Technology in September of 1999, where he is now the C.P. Dubbs Professor of Chemical Engineering and Biological Engineering, in addition to working with the Koch Institute as the Associate Director for Engineering.

Principal Scientist & Group Leader

Weifeng has been in the field of immunogenicity for biologics for about 10 years. He had developed cell-based neutralization Ab assays for multiple key product at BMS including Opdivo and Yervoy. He is an active member in AAPS NAb work group as well as EBA NAb team; he is also co-leading the NAb assay drug tolerance subteam at AAPS. After join Merck at the end of 2018, Weifeng is now leading Cell Assay group within PPDM Regulated Immunogenicity to develop neutralizing assays for both biologics and vaccines.

Assoc Principal Scientist

Kun Yang, Ph.D. is currently an Associate Principal Scientist at Regulated PK Bioanalysis within the Department of Pharmacokinetics, Pharmacodynamics, and Drug Metabolism (PPDM) in Merck Research Laboratories. In PPDM BA, Kun is responsible for critical reagents generation and characterization strategy to support regulated preclinical and clinical studies for biologics and vaccines. In addition, he was a technical lead in the development and validation of bioanalytical assays at Merck. Kun has 10 years’ experience at leading pharmaceutical companies and was working on vaccines, small molecule, and biological drugs. Kun was responsible for the development of clinical and manufacturing processes for new therapeutic protein candidates. Kun’s technical expertise includes preclinical and clinical pharmacokinetics pharmacodynamics, absolute quantification of biologics molecules by immunocapture-LC/MS/MS and LBA in biological matrices to support PK for pre-clinical and clinical studies, and ADME. Kun also has extensive experience with bioprocess (from preclinical batch to clinical batch) including cell culture, purification and analytical characterization, process optimization, process characterization, process scale-up, technology transfer, validation, and biomanufacturing. Kun received his Ph.D. in Biochemistry from University of Texas Southwestern Medical Center at Dallas.

Staff Scientist & Grp Leader LMBB

Alexei Yeliseev is a Staff Scientist, head of the protein biochemistry group at the National Institute on Alcoholism and Alcohol Abuse, National Institute of Health. His research focuses on developing technologies for expression, purification, and functional and structural characterization of G protein-coupled receptors. In addition to his research work he serves as a member of editorial board of Protein Expression and Purification.

Principal Scientist

Dr. Junming Yie is a Principal Scientist in the cell-based assay group of the Biologics Anayltical R&D in process development at Merck & Co.. Having been in the biotech/pharmaceutical industry since 2001, Dr. Yie have spent six years at Pfizer and eight years at Amgen before joining Merck in 2015. Considering himself as expert in metabolic diseases, Dr. Yie spent his first 15 industrial years in the discovery research, mainly focused on the metabolic diseases such as diabetes, obesity, NASH, muscular and cardiovascular diseases. During this period, Dr. Yie have worked on more than a dozen projects and have led a few projects from conceptual ideas to the delivery of clinical candidates. Dr. Yie have led projects for delivering two monoclonal antibodies from two different projects, three small molecule candidates, and has been a key contributor for delivering three recombinant protein candidates into clinical development. Having seen enough discovery research, Dr. Yie moved into the current role in the cell-based assay group of Biologics AR&D, and started to learn the knowledge in bioprocess and CMC. Dr. Yie first worked on a biosimilar program, and developed a functional cell-based assay to replace USP<121> rabbit blood sugar bioidentity assay. He learned to appreciate the rigorous criteria of assay development for GMP and GLP purposes. Later on, Dr. Yie and his team has developed serveral cell-based assays for projects in immuno-oncology, virology and metabolic diseases. Dr. Yie is also leading an analytical effort as analytical project leader for a Phase 3 bioprocess development, and has taken the new challenges to expand his knowledge across CMC realm.

Senior Scientist

Dr. Xinchao Yu is a senior scientist and cryo-EM group leader at Amgen-Thousand Oaks. Xinchao received his Ph.D. in Biophysics from Boston University with comprehensive training in single particle cryo-EM. During his postdoctoral career at the Memorial Sloan Kettering Cancer Center, he used a combination of X-ray crystallography and cryo-EM to study molecular machineries involved in membrane trafficking processes, as well as honing his expertise in membrane protein expression and purification. With a passion to pursue innovative medicine to help patients, Xinchao joined Amen in 2015 to lead the cryo-EM initiative to set up the cryo-EM infrastructure to support drug discovery. Through extensive cross-functional and cross-site collaborations, Xinchao and the cryo-EM team have made significant progress to support a number of important research pipelines, including several challenging membrane protein targets.

Research Associate

Shlomo Zarzhitsky is a research associate at Princeton University working with Prof. Michael Hecht. His research focuses on the utilization of synthetic proteins in the expression of Difficult-to-Express-Proteins. Shlomo is a biotechnology engineer with extensive experience in the design and characterization of peptides and proteins.

Principal Scientist

Dr. Mei-Yun Zhang obtained her B.A. and M.S. degrees from China Agricultural University, and Ph.D. in Natural Science from Aachen Technical University, Germany. After a postdoc training in NCI, NIH, she was promoted to Scientist. She was appointed Assistant Professor and served as a Faculty member in the Department of Microbiology, The University of Hong Kong. She then moved on to biotech industry and joined Amgen in 2015 as Principal Scientist, Antibody Discovery Lead at Amgen China R&D Center. She has conducted extensive basic researches in cancer and infectious diseases and led biologics drug early discovery throughout her career. She has 58 peer-reviewed publications and holds 7 issued patents or patent applications. Since she joined Amgen, she has been focused on developing innovative technologies for antibody discovery and established camelid single domain antibody platform and antibody phenotypic screening platform at Amgen.

Assoc Prof

Dr. Zhang has been trained as a physician and then earned a PhD in Cell Biology in Chinese Academy of Medical Sciences & Peking Union Medical College. Following a CRI postdoctoral fellowship at the University of Chicago, he began his independent career at the University of Texas Health Science Center at San Antonio, as an Assistant Professor of Medicine. Subsequently, Dr. Zhang moved his research laboratory to Northwestern University where he is currently Professor of Medicine, and Microbiology-Immunology, as well as Co-Director of Immune Assessment Core, at the Robert H. Lurie Comprehensive Cancer Center. The Zhang group focuses on integrated translational research program with the goal of designing and developing new immunotherapies and immunologic strategies for cancer treatment together with an interdisciplinary approach to nanomaterials research. His work has directly promoted the initiation of a number of clinical trials. Dr. Zhang has published over 90 scientific papers, many in high-impact journals including Immunity, J Exp Med, Nat Commun, PNAS, and J Clin Invest. He has been serving as Editors of several leading journals including J Immunol and Front Oncol. Dr. Zhang has also served on several NIH study sections and currently is standing member of the National Institutes of Health (NIH) Cancer Immunopathology and Immunotherapy (CII) study section. Dr. Zhang’s research has been continuously funded for more than two decades by NCI, DOD and other federal, state and private funding agencies.

Principal Scientist & Leader & Section Head

Dr Zhao obtained her PhD at Manchester University and gained her postdoctoral experiences at the University of Oxford, CR-UK Cancer Institute and UCL before joining NIBSC in 2001. She has a strong background in gene therapy, virology, molecular biology, cell biology, cancer research and developmental biology. Her research interests lie in vector development based on Retrovirus, Parvovirus and Baculovirus. She has been an active Expert member of EMA/CAT Gene Therapy Working Party, EDQM/OMCL gene therapy group, ICH and ISO Drafting Group, contributing to the development of European and International Guidance on Advance Therapies.

CSO

Dr. Zhukovsky has over two decades of experience in the biotherapeutics R&D. He applies optimized monospecific and novel bispecific antibody platforms to the development of immunotherapeutics for cancer, with a particular focus on leveraging the biology of immune checkpoint modulators. He is the CSO of Biomunex Pharmaceuticals where he realigned the company’s strategic focus towards immuno-oncology therapeutics by leveraging its bispecific antibody platform, the BiXAb®. He is also Co-Founder and Partner at ZM Scientific LLC, a consultancy firm that advises biotechnology companies, specifically in the area of bispecific, optimized and native antibody development from discovery to first-in-human studies. Previously, Dr. Zhukovsky served as the CSO of Affimed. Prior to that he was a Senior Research Fellow at Boehringer Ingelheim Pharmaceuticals, Inc., and an Associate Director at Xencor, Inc. A BLA for tafasitamab, a program that he proposed and led, has recently been submitted to the FDA. Dr. Zhukovsky performed a postdoctoral fellowship at Genentech, Inc. He received a PhD in biochemistry from Brandeis University.

Professor

Jan-Willem de Gier is Professor of Biochemistry at Stockholm University. Main interest of his laboratory is the creation of E. coli recombinant protein production strains. To this end, both evolutionary and engineering approaches are used. In addition, he is Co-Founder of the biotechnology companies, Xbrane Biopharma AB and Abera Bioscience AB.

Research Fellow

PhD in cell biology. 10 years’ experience in antibody engineering. Was responsible for pre-clinical development of ARGX-115, targeting GARP-TGFβ1, for immuno-oncology, until AbbVie took over for clinical development. Lead scientist TGFβ-related projects and project leader on the ARGX-118 project for severe asthma.


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